(n.) A young or inferior devil; a little, malignant spirit; a puny demon; a contemptible evil worker.
(n.) Something added to, or united with, another, to lengthen it out or repair it, -- as, an addition to a beehive; a feather inserted in a broken wing of a bird; a length of twisted hair in a fishing line.
(n.) To graft; to insert as a scion.
(n.) To graft with new feathers, as a wing; to splice a broken feather. Hence, Fig.: To repair; to extend; to increase; to strengthen to equip.
Example Sentences:
(1) Intramembrane particles (IMP) were quantitatively assessed in the perikaryal plasma membranes of infundibular neurons.
(2) The inhibition by TAD of IMP DH activity in ovarian carcinomas (N = 4) was 81%.
(3) Incubation of I diaphragms with isoproterenol did not significantly increase the concentrations of AMP, IMP or inorganic phosphate, activators of phosphorylase beta activity, nor was there a decrease in ATP and glucose 6-phosphate content, allosteric inhibitors of phosphorylase beta activity.
(4) Second, interconversion of adenine nucleotides to guanine nucleotides, is curtailed by the inhibition of IMP dehydrogenase by these same IMP analogues.
(5) Under optimal reaction conditions, HhaI and RsaI cleaved the DMTS-std duplex to 76-77% completion and the DMTS-imp duplex to 96-99% completion.
(6) The incorporation of inosine or hypoxanthine into the IMP and ITP has been proved.
(7) At all times, a tight inverse correlation exists between ATP and IMP concentrations.
(8) It was concluded that the IMP content of human skeletal muscle is very low at rest and after low-intensity exercise, but increases after moderate and high-intensity exercise.
(9) The synthetic "C" nucleoside, tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide), its selenium analogue selenazofurin, and the related inhibitor of inosine 5'-phosphate (IMP) dehydrogenase, mycophenolic acid, are effective inducers of the terminal differentiation of HL-60 promyelocytic leukemia cells.
(10) After 60 min recovery, exercise was performed for 8-10 min each at 20, 30, 40 and 50 W. Measurements of pulmonary oxygen uptake, heart rate, blood pressure, leg blood flow, and femoral arterial-venous differences of oxygen content and lactate were performed as well as determination of ATP, creatine phosphate (CP) inosine monophosphate (IMP) and lactate concentrations on biopsy material from the quadriceps muscle before and immediately after the intense exercise, and at 3, 10 and 60 min into recovery.
(11) Virazole 5'-phosphate was subsequently found to be a potent competitive inhibitor of inosine 5'-phosphate dehydrogenase (IMP:NAD(+) oxidoreductase, EC 1.2.1.14) isolated from Escherichia coli (K(m) = 1.8 x 10(-5) M) with a K(i) of 2.7 x 10(-7) M. Guanosine 5'-phosphate (GMP) was a competitive inhibitor of this enzyme with a K(i) of 7.7 x 10(-5) M. Virazole 5'-phosphate was similarly active against IMP dehydrogenase isolated from Ehrlich ascites tumor cells, with a K(i) of 2.5 x 10(-7) M. The K(m) for this enzyme was 1.8 x 10(-5) M, and the K(i) for GMP was 2.2 x 10(-4) M. These results suggest that the antiviral activity of Virazole might be due to the inhibition of GMP biosynthesis in the infected cell at the step involving the conversion of IMP to xanthosine 5'-phosphate.
(12) Initial rate kinetic studies demonstrate the ppGpp inhibition is competitive with respect to GTP and noncompetitive with respect to L-aspartate and IMP.
(13) Uptake of IMP was calculated from the arteriovenous difference of 14C-IMP across the lung and lung effluents and homogenates were analyzed for the presence of metabolites of IMP.
(14) During continuous isometric exercise with constant stimulation time, the amount of IMP was linearly and inversely related to the age of the animals; a higher IMP concentration was found in intermittent isometric and dynamic exercise.
(15) We evaluated the effect of high partial pressures of O2 on pulmonary uptake and metabolism of IMP.
(16) Thus, 123I-IMP and 99mTc-HM-PAO SPECTs seemed to be a useful tool in the diagnosis, deciding of whether the treatment was suspended or continued, and clarifying the pathophysiology in HSE.
(17) It was considered that the analysis of the lung release of 123I-IMP forms a new lung dysfunction index.
(18) The increased activity in cancer cells of inosine 5'-monophosphate dehydrogenase (IMP DH, EC 1.1.1.205), the rate-limiting enzyme of de novo GTP biosynthesis, was suggested as a sensitive target for chemotherapy.
(19) To determine the biochemical mechanisms of cytotoxicity of these drugs, assay procedures have been developed for measurement of the levels of intermediates proximal to IMP in the pathway for de novo purine biosynthesis in mouse L1210 leukemia cells.
(20) Our review indicates that 123I-IMP SPECT may have an important future role in the early diagnosis and management of patients with acute infarctive stroke and AD.
Vampire
Definition:
(n.) A blood-sucking ghost; a soul of a dead person superstitiously believed to come from the grave and wander about by night sucking the blood of persons asleep, thus causing their death. This superstition is now prevalent in parts of Eastern Europe, and was especially current in Hungary about the year 1730.
(n.) Fig.: One who lives by preying on others; an extortioner; a bloodsucker.
(n.) Either one of two or more species of South American blood-sucking bats belonging to the genera Desmodus and Diphylla. These bats are destitute of molar teeth, but have strong, sharp cutting incisors with which they make punctured wounds from which they suck the blood of horses, cattle, and other animals, as well as man, chiefly during sleep. They have a caecal appendage to the stomach, in which the blood with which they gorge themselves is stored.
(n.) Any one of several species of harmless tropical American bats of the genus Vampyrus, especially V. spectrum. These bats feed upon insects and fruit, but were formerly erroneously supposed to suck the blood of man and animals. Called also false vampire.
Example Sentences:
(1) Clinically the word vampirism should be used to name all sexual or agressive acts, whether blood-sucking happens or not, committed on a dead or dying person.
(2) Leather, who celebrated his seventh consecutive week at the top of the Amazon chart with his novella The Basement , about a serial killer in New York, also occupies fourth place with Hard Landing , another thriller, and 11th place with Once Bitten , a vampire novel.
(3) The Buffy the Vampire Slayer creator's bosses at Marvel are also bringing sequels to Thor and Captain America to the big screen over the next year, a fact which would also appear to clash with Whedon's clarion call for originality.
(4) Like it or not, he went on to direct another vampire movie, Scars of Dracula (1970), with Christopher Lee in the title role and bad special effects such as rubber bats on strings.
(5) Her most memorable film role to date has been dancing with a python in a state of undress in the vampire movie From Dusk Till Dawn.
(6) He developed a parallel career as a rock video director after mentioning in a meeting with record label and film company Warp that he loved the Arctic Monkeys, and ended up directing a string of videos for them (given the band's legendary reticence, the mind boggles at what the initial meeting was like) as well as Vampire Weekend , Kasabian and the Yeah Yeah Yeahs .
(7) It takes place over roughly two days and two nights, as Ben and his new friends – or what's left of them – try to end the rapidly spreading vampire menace and take Salem's Lot back.For better or worse, the book ends pretty much where it began: with the tall man and the boy in Mexico, trying to work out their next move.
(8) Vampire bat salivary plasminogen activator (BatPA), human tissue-type plasminogen activator (tPA) or streptokinase (SK) were incubated in human citrated plasma containing a plasma clot that was radiolabelled with iodine-125 fibrin(ogen).
(9) For us, it’s a human question,” he said, insisting that Qataris were not “vicious people who are like vampires.
(10) He found Madonna's interest in him almost vampiric.
(11) We didn’t tell him how central his role was, we didn’t want to make him nervous.” It’s notable that after gallivanting around the globe for centuries, Clement and Waititi’s vampires have settled in Wellington, New Zealand.
(12) Blackout will be organising grassroots events, nationwide, for people to come out and show their solidarity in the fight for equal human rights.” Backers include Fruitvale Station actor Michael B Jordan, Vampire Diaries star Kat Graham, hiphop mogul Russell Simmons and erstwhile Rage Against the Machine guitarist Tom Morello.
(13) The idea of the vampire as a silver-tongued aristocrat, like Count Dracula, is mirrored in Irving's thespian mannerisms, and his fascination with theatrical villains.
(14) But vampires and zombies are old news, according to Quirk.
(15) A comparison to the development and function of night-mares is drawn.--The vampire motif in Europe originally developed at the end of the Middle Ages.
(16) Beyond the strangers in internet chatrooms, where I discussed the subtextual relationship between Buffy the Vampire Slayer and evil slayer Faith, no one said I was allowed to feel like this.
(17) Some were dismissive: "Patricia Hewitt and Geoff Hoon have as much impact as a vampire with no teeth," wrote Welshracer.
(18) Lessons learned ... Feminism is dead Over the 476 minutes of vampires, wolves and long, lingering looks, Bella's life (much like life after 30) is a depressing trudge towards marriage and babies.
(19) "I wanted to make Vampire's Kiss, because I was still trying to live my punk rock dreams.
(20) The one place Vampire Weekend really let loose, it seems, is in the studio.