(a.) Not permeable; not permitting passage, as of a fluid. through its substance; impervious; impenetrable; as, India rubber is impermeable to water and to air.
Example Sentences:
(1) On the other hand, changing pH on only one side by addition of an impermeant buffer fails to induce any change in n. At the single-channel level, pH had an effect both on the unitary conductance, doubling it in going from pH 4.5 to 8.2, as well as on the fraction of time the channels stay open, F(v).
(2) EAI can penetrate a membrane, whereas IAI is membrane impermeant.
(3) Both the internal and external solutions were prepared with impermeant anions.
(4) Replacement of Cl-o with other impermeant anions, such as gluconate and methylsulphate, had a similar action on contractile activity as for Ise-replacement.
(5) When sulfhydryl groups present at the cell surface were blocked with cell-impermeant sulfhydryl reagent, the initial phase of disulfide cleavage was inhibited, indicating that cleavage began at the cell surface.
(6) To explain the opposite effects of GTP in the absence and presence of oxalate, it is proposed that GTP activates a transmembrane conveyance of Ca2+ between oxalate-permeable and -impermeable compartments.
(7) Measurement of (140)La uptake by the living skin shows that lanthanum moves across the external surface of the skin readily, into and out of a compartment that has a limited capacity and is bounded on its internal side by a barrier impermeable to lanthanum.
(8) When permeant anions in the bath (Cl-) were replaced with relatively impermeant anions (gluconate, MOPS, propionate, or Hepes), the Po vs. voltage relationship was shifted by approximately -35 mV.
(9) Currents through both the voltage-activated potassium channels, IK,V, and the calcium-activated potassium channels, IK,Ca, can be blocked by the membrane-impermeant K channel blocker tetraethylammonium (TEA).
(10) The outcome is a belief that the Earth is being slowly strangled by a gaudy coat of impermeable plastic waste that collects in great floating islands in the world's oceans; clogs up canals and rivers; and is swallowed by animals, birds and sea creatures.
(11) Local hypoxia due to a diffusion block by the impermeable pericapillary cuffs, partially due to a reduction of capillaries in the superficial layers.
(12) The connective hyperpolarizes in the propionate saline, whereas the abdominal region undergoes the transient depolarization that is expected when a permeant anion (Cl) is replaced with an impermeant one (propionate).
(13) In forest, removal of olfactory substances from the human skin, by vigorous washing and application of petroleum jelly, or by wearing impermeable clothing, greatly reduced the numbers of flies attracted.
(14) By the use of double-chamber tissue culture flasks, with the 2 cell populations separated by a cell impermeable membrane, it was found that T-T interaction does not require cell contact and is thus mediated by factor(s).
(15) This discrepancy could be ascribed to impermeability, as E. coli cells with modified permeability show greater sensitivity to minosaminomycin.
(16) The perinephric membrane in the Lepidoptera is impermeable to the dyes.
(17) The relatively membrane-impermeant pyridoxal phosphate labels all proteins of the intact myelin except basic protein.
(18) Monobromobimane and dibromobimane are effective on intact cells while red cell membranes may be impermeable to the positively charged monobromotrimethylammoniobimane, the latter being effective only on lysed cells.
(19) This failure was shown to be due to the impermeability of mycobacteria to these drugs by use of "membrane-active" agents along with the antibiotics in growth inhibition studies.
(20) Chloride dependence was assessed by replacing chloride with the impermeant anion gluconate, or by addition of the anion transport blocker 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS).
Inaccessible
Definition:
(a.) Not accessible; not to be reached, obtained, or approached; as, an inaccessible rock, fortress, document, prince, etc.
Example Sentences:
(1) Two-thirds of the cytoplasmic water is inaccessible to sucrose and is designated c2.
(2) These are usually located in the intracranial part of the vertebral artery and less frequently in the lower basilar artery, and are therefore inaccessible to prophylactic vascular surgery.
(3) Unfortunately, transitional cell carcinoma may involve other regions of the prostate that are inaccessible by cystoscopy.
(4) Acquisition of Ab inaccessibility occurred very efficiently in this cell-free system (approximately 50% of total cell-associated 125I-BSST became inaccessible) and could be inhibited by anti-clathrin mAbs and by antibodies directed against the cytoplasmic domain of the transferrin-receptor.
(5) Inaccessibility of essential health information to the women most affected, and the physical as well as economic and sociocultural distance separating health services from the vast majority of women, are only part of the problem.
(6) It also provides important details about potential surgical routes to this relatively inaccessible region.
(7) Bypass of surgically inaccessible stenoses or occlusions appears to be a logical technique to prevent future stroke but there is much uncertainty about the clinical indications for surgery and even the natural history of the lesions being bypassed.
(8) In 2019, the long-awaited Crossrail project is due to open, but up until a few weeks ago, seven of the 38 stations on the route were set to remain inaccessible.
(9) Because of the mild and focal nature of the inflammatory infiltrates and involvement of regions inaccessible to the bioptome, sampling error contributes appreciably to false-negative results in endomyocardial biopsy tissue from patients with myocarditis.
(10) The dissociation constant of ATP from the unligated enzyme, a constant that has previously been experimentally inaccessible, has been measured for wild-type and several mutant enzymes.
(11) We must urgently tackle this culture of inaccessible politics.
(12) The problems faced in the prevention and control of malaria include problems associated with the opening of land for agriculture, mobility of the aborigines of Peninsular Malaysia (Orang Asli) and inaccessibility of malaria problem areas.
(13) However, in less than 15 sec, LTB4-treated PMN lose the ability to respond further to LTB4; decrease the affinity and number of high affinity receptors available for binding LTB4; sequester LTB4 in plasmalemma-associated sites that are inaccessible to a releasing buffer regimen; and begin internalizing LTB4.
(14) The species-specific inactivation in concluded from various lines of evidence to be ATP-site-directed and is attributed to alkylation of an amino acid residue of the rabbit enzyme which in the pig and carp enzymes is absent, inaccessible, or less reactive.
(15) Because the three major proteins of the Karp and Gilliam strains are accessible to antibody in unextracted organisms, it is possible that the exteriorly exposed epitopes of these three polypeptides are strain specific and that their common determinants are normally buried in the membrane or otherwise inaccessible.
(16) This decrease in PI-PLC sensitivity may reflect an alteration in the PI-glycan anchoring structures, or in a general membrane property, which renders the PI-anchored proteins inaccessible to the enzyme.
(17) A deficit in, or the inaccessibility of, J chain protein appears to facilitate hexamer formation.
(18) We have already introduced a vacuum drainage system, which is a special drainage system through a machine that removes water, but we cannot do anything about the climate of the Amazon.” Bastos went on to outline the problems with maintaining a pitch in such an inaccessible part of Brazil.
(19) We discuss the possibility that a shift in equilibrium between accessible and inaccessible transporters is operating.
(20) One of the physiological consequences of these interactions is that polymorphonuclear leukocytes stimulated with either chemoattractants or TNF form protected compartments at their interface with fibrinogen-coated surfaces and that elastase released into these compartments is inaccessible to protease inhibitors present in the plasma.