(a.) Not permeable; not permitting passage, as of a fluid. through its substance; impervious; impenetrable; as, India rubber is impermeable to water and to air.
Example Sentences:
(1) On the other hand, changing pH on only one side by addition of an impermeant buffer fails to induce any change in n. At the single-channel level, pH had an effect both on the unitary conductance, doubling it in going from pH 4.5 to 8.2, as well as on the fraction of time the channels stay open, F(v).
(2) EAI can penetrate a membrane, whereas IAI is membrane impermeant.
(3) Both the internal and external solutions were prepared with impermeant anions.
(4) Replacement of Cl-o with other impermeant anions, such as gluconate and methylsulphate, had a similar action on contractile activity as for Ise-replacement.
(5) When sulfhydryl groups present at the cell surface were blocked with cell-impermeant sulfhydryl reagent, the initial phase of disulfide cleavage was inhibited, indicating that cleavage began at the cell surface.
(6) To explain the opposite effects of GTP in the absence and presence of oxalate, it is proposed that GTP activates a transmembrane conveyance of Ca2+ between oxalate-permeable and -impermeable compartments.
(7) Measurement of (140)La uptake by the living skin shows that lanthanum moves across the external surface of the skin readily, into and out of a compartment that has a limited capacity and is bounded on its internal side by a barrier impermeable to lanthanum.
(8) When permeant anions in the bath (Cl-) were replaced with relatively impermeant anions (gluconate, MOPS, propionate, or Hepes), the Po vs. voltage relationship was shifted by approximately -35 mV.
(9) Currents through both the voltage-activated potassium channels, IK,V, and the calcium-activated potassium channels, IK,Ca, can be blocked by the membrane-impermeant K channel blocker tetraethylammonium (TEA).
(10) The outcome is a belief that the Earth is being slowly strangled by a gaudy coat of impermeable plastic waste that collects in great floating islands in the world's oceans; clogs up canals and rivers; and is swallowed by animals, birds and sea creatures.
(11) Local hypoxia due to a diffusion block by the impermeable pericapillary cuffs, partially due to a reduction of capillaries in the superficial layers.
(12) The connective hyperpolarizes in the propionate saline, whereas the abdominal region undergoes the transient depolarization that is expected when a permeant anion (Cl) is replaced with an impermeant one (propionate).
(13) In forest, removal of olfactory substances from the human skin, by vigorous washing and application of petroleum jelly, or by wearing impermeable clothing, greatly reduced the numbers of flies attracted.
(14) By the use of double-chamber tissue culture flasks, with the 2 cell populations separated by a cell impermeable membrane, it was found that T-T interaction does not require cell contact and is thus mediated by factor(s).
(15) This discrepancy could be ascribed to impermeability, as E. coli cells with modified permeability show greater sensitivity to minosaminomycin.
(16) The perinephric membrane in the Lepidoptera is impermeable to the dyes.
(17) The relatively membrane-impermeant pyridoxal phosphate labels all proteins of the intact myelin except basic protein.
(18) Monobromobimane and dibromobimane are effective on intact cells while red cell membranes may be impermeable to the positively charged monobromotrimethylammoniobimane, the latter being effective only on lysed cells.
(19) This failure was shown to be due to the impermeability of mycobacteria to these drugs by use of "membrane-active" agents along with the antibiotics in growth inhibition studies.
(20) Chloride dependence was assessed by replacing chloride with the impermeant anion gluconate, or by addition of the anion transport blocker 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS).
Permeate
Definition:
(v. t.) To pass through the pores or interstices of; to penetrate and pass through without causing rupture or displacement; -- applied especially to fluids which pass through substances of loose texture; as, water permeates sand.
(v. t.) To enter and spread through; to pervade.
Example Sentences:
(1) In both instances the permeation rates of proteins can be better correlated to hydrodynamic radii than to molecular weights.
(2) In anaerobiosis, at 25 mM sulphanilic acid, or with addition of p-toluene sulphonic acid only one regression line is obtained for the permeation in both directions.
(3) The calpains were allowed to autolyze to completion, and the autolysis products were separated and were characterized by using gel permeation chromatography, calpastatin affinity chromatography, and sequence analysis.
(4) At 5 micrometer and 2.5 mM sulphanilic acid under aerobic conditions, the regression lines for the permeation from lumen to blood pass almost through the origin, while the regression lines for the permeation from blood to lumen intersect the ordinate at a positive Y-value.
(5) The breakthrough time and permeation rate at steady-state were calculated as described in the ASTM standard test method.
(6) Insulin-like growth factor-binding proteins (IGFBPs) in rat serum, lymph, amniotic fluid and cerebrospinal fluid (CSF), and in rat cell-conditioned media were characterized using a combination of gel-permeation chromatography, Western immunoblots and Western-ligand analysis.
(7) Glycerol permeation and thus its osmotic action may be less in the soleus than in other muscles.
(8) Previous histological evidence of the uptake of these particles and their absorption across the gastrointestinal tract and passage via the mesentery lymph supply and lymph nodes to the liver and spleen was confirmed by analysis of tissues for the presence of polystyrene by gel permeation chromatography.
(9) 10% NNDEMT doubled the amount of PFA in the skin, increased fourfold the amount permeated across the skin, and increased the flux fivefold.
(10) Various methodological weaknesses permeate the relevant literature.
(11) Time courses for in vivo total mucosal uptake exhibited linearity over a wide variety of absorption rates after correction for the permeation by intact metal-chelate complex.
(12) Gel permeation chromatography of the CIT-agarose eluates revealed one protein peak that coincided with PDE activity at an elution position of 135,000 daltons.
(13) Phospholipase A2 has been purified from the venom of Horned viper (Cerastes cerastes) by gel permeation chromatography followed by reverse-phase HPLC.
(14) The buccal absorption characteristics and physicochemical properties of the beta-adrenoceptor blocking agents propranolol and atenolol have been investigated to evaluate their permeation properties across biological lipid membranes.
(15) The permeation enhancer STDHF increases mucosal permeability and reduces the average molecular weight of the insulin species.
(16) I argue that the energy profile in the permeation pathway of most biological channels should vary relatively smoothly with only a few localized energy barriers or wells.
(17) Channels containing a variety of viable cells permeated the rice bodies.
(18) Estrogen receptor from human breast cancer tissue and from normal human uterus was isolated and characterized by a combination of physical separation methods including ammonium sulfate precipitation, gel permeation chromatography, isoelectric focusing and gel electrophoresis.
(19) However, we did not examine the mechanisms by which the apparent high permeation of sodium chloride occurs.
(20) For the skins without stratum corneum, the permeation rates and permeation amounts of l-NG and dl-NG were higher than those for the intact skin (P less than 0.01), but no significant difference was seen between l-NG and dl-NG.