(n.) The quality or state of being important; consequence; weight; moment; significance.
(n.) Subject; matter.
(n.) Import; meaning; significance.
(n.) Importunity; solicitation.
Example Sentences:
(1) CT appears to yield important diagnostic contribution to preoperative staging.
(2) This paper discusses the typical echocardiographic patterns of a variety of important conditions concerning the mitral valve, the left ventricle, the interatrial and interventricular septum as well as the influence of respiration on the performance of echocardiograms.
(3) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(4) Glucocorticoids have numerous effects some of which are permissive; steroids are thus important not only for what they do, but also for what they permit or enable other hormones and signal molecules to do.
(5) Trifluoroacetylated rabbit serum albumin was 5 times more reactive with these antibodies and thus more antigenic than the homologous acetylated moiety confirming the importance of the trifluoromethyl moiety as an epitope in the immunogen in vivo.
(6) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(7) However it is important to recognize these cysts so that correct surgical management is offered to the patient.
(8) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(9) Under blood preservation conditions the difference of the rates of ATP-production and -consumption is the most important factor for a high ATP-level over long periods.
(10) This finding is of major importance for persons treated with diltiazem who engage in sport.
(11) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(12) Because of the dearth of epidemiological clues as to causation, studies with experimental animal models assume greater importance.
(13) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(14) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(15) Nutritional factors or environmental toxins have important effects on CNS degenerative changes.
(16) Moreover, homozygous deletion of the FMS gene may be an important event in the genesis of the MDS variant 5q- syndrome.
(17) Importantly, these characteristics were strong predictors of subsequent mortality.
(18) As the requirements to store and display these images increase, the following questions become important: (a) What methods can be used to ensure that information given to the physician represents the originally acquired data?
(19) Periosteal chondroma is an uncommon benign cartilagenous lesion, and its importance lies primarily in its characteristic radiographic and pathologic appearance which should be of assistance in the differential diagnosis of eccentric lesions of bones.
(20) As important providers of health care education, nurses need to be fully informed of the research findings relevant to effective interventions designed to motivate health-related behavior change.
Rationale
Definition:
(a.) An explanation or exposition of the principles of some opinion, action, hypothesis, phenomenon, or the like; also, the principles themselves.
Example Sentences:
(1) Topical and systemic antibiotic therapy is common in dermatology, yet it is hard to find a rationale for a particular route in some diseases.
(2) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(3) The rationale for using the high-risk-group research design in the search for the aetiology of schizophrenia is described.
(4) Pathophysiologic mechanisms and rationale for treatment are discussed.
(5) The rationale for this assumption seems logical because using all of the available accommodation is not sustainable without discomfort.
(6) The rationale for the use of exercise as part of the treatment program in type II diabetes is much clearer and regular exercise may be prescribed as an adjunct to caloric restriction for weight reduction and as a means of improving insulin sensitivity in the obese, insulin-resistant individual.
(7) The rationale for diagnosis and therapy is discussed.
(8) The rationale for the inclusion of Mg in cardioplegic solutions therefore lies not in its cardioplegic properties, but in its ability to influence other cellular events such as the loss of Mg and K and perhaps to counter the detrimental effects of ischemia by antagonizing calcium (Ca) overload.
(9) The rationale for using videofluoroscopy for rehabilitation, the implementation of videofluoroscopy for rehabilitation, and indications for using specific rehabilitation techniques during videofluoroscopy will be discussed.
(10) The rationale for pursuing the development and use of germ-line selection and modification techniques is examined in this essay.
(11) An experimental murine malarial model was devised using the highly synchronous species Plasmodium vinckei petteri to test this rationale.
(12) The wide variety of neurobehavioral effects produced by chemicals found in the environment argues for a rationale of tailoring test selection in many situations, particularly those where the range of expected effects has been fairly well established for the chemical under study.
(13) The homology thus revealed not only lends strong support to mechanisms of autoimmunity that invoke the theory of molecular mimicry of viral proteins, but also suggests a rationale for the skeletal muscle target of polymyositis.
(14) The relationship of these findings to the rationale of such procedures as segmental resection in the surgical treatment of breast cancer is discussed.
(15) The rationale of the method is outlined with emphasis on the management of traumatic oedema.
(16) Concluding the two-page survey were open-ended questions addressing the respondent's indications, contraindications, and rationale for using or not using fluoroscopy.
(17) This advantage may provide a rationale for further evaluation of this agent in patients with more widespread ventricular dysfunction.
(18) The evolution of and rationale for the combined surgical approach to coexistent carotid and coronary artery disease is discussed and the literature reviewed.
(19) Whether there is an additional cost-benefit rationale for handwashing with an antimicrobial agent remains to be studied.
(20) The first reviews the problems of heat stress evaluation: it describes the comprehensive approach adopted by ISO standards and in particular the rationale of the Required Sweat Rate index, and presents the work done during the ECSC interlaboratory study, which extends the application of this index to intermittent or fluctuating conditions of exposure.