What's the difference between impurity and purification?

Impurity


Definition:

  • (n.) The condition or quality of being impure in any sense; defilement; foulness; adulteration.
  • (n.) That which is, or which renders anything, impure; foul matter, action, language, etc.; a foreign ingredient.
  • (n.) Want of ceremonial purity; defilement.

Example Sentences:

  • (1) Two other impurities are pyrene derivatives but their acyl chains probably are not decanoic acid.
  • (2) No impurities in the technical grade ether influenced the responses.
  • (3) The UV and IR absorption spectra of compounds present in the eluate were compared with those of model compounds that were assumed to exist in the gel as impurities after the polymerization (monomers and oligomers of hydroxyethyl methacrylate, decomposition products of initiators).
  • (4) Chloramphenicol, dinitrophenol, and impurities present in some brands of agar all appear to inhibit the growth-medium-dependent branch of excision-repair.
  • (5) The combined results describe the depth of segregation of DMS blocks in Avcothane, the presence of DMS within the topmost 20 A in Biomer, and similar impurities in the model polymers.
  • (6) An impure sample of PLC inhibited sperm penetration, while a more purified preparation did not.
  • (7) A liquid chromatographic (LC) method was adapted for the determination of epinephrine and related impurities in intravenous and cardiac injections; ultraviolet (UV) and electrochemical detectors (EC) were used in series.
  • (8) The determination of potency or shelf life, impurity limit testing, and study of reaction mechanisms are considered as different aspects of drug stability.
  • (9) Isolated cytochrome c oxidase was fractionated by native-gel electrophoresis in Triton X-100, and a preparation of enzyme almost completely free of the usual impurities was recovered.
  • (10) Although these are worst case calculations, a consistent approach should be reconsidered to limit the additional effective dose equivalent from impurities to e.g.
  • (11) As little as 50 nmol of a protein may be quantified and an impurity peak of molecular weight ca.
  • (12) Not all impurities were found in every lot of drug investigated, and none of the impurities exceeded a concentration of 1% of the meperidine present.
  • (13) Skin impurities and fatty hair associated with acne were side effects in 22.5% of 378 patients during the first evaluation and in 10.8% of 369 patients at the second evaluation.
  • (14) The organic solvent soluble impurities exhibited strong mutagenic activity for TA98 and slight activity for TA100.
  • (15) Following this order the absorbents can be used for purification of human albumin from non-specific impurities taking into account stronger adsorption of albumin or impurities.
  • (16) Trace amounts of an impurity commonly produced in the synthesis of 1,2-distearoyl-3-sn-phosphatidylcholine, 1,3-distearoyl-2-sn-phosphatidylcholine, are found to dramatically reduce the rate of loss of small vesicles at 21 degrees C.
  • (17) It is shown on the basis of calculations of energy sublevels of the hyperfine structure that the effect of the geomagnetic field upon the impurity atoms in the volume of living cells should be considered in relation to the value of geomagnetic field induction pulses delta B.
  • (18) Contamination of cells by impurity atoms that may leach from electrodes was measured by atomic-absorption spectrophotometry and found to be negligible.
  • (19) Results presented here indicate that N-nitroso compound impurities are absent from the majority of the products tested.
  • (20) Eight of the proteins (L9, L11, L13, L21, L22, L35', L37 and L39) had no detectable contamination; the impurities in the others were no greater than 9%.

Purification


Definition:

  • (n.) The act of purifying; the act or operation of separating and removing from anything that which is impure or noxious, or heterogeneous or foreign to it; as, the purification of liquors, or of metals.
  • (n.) The act or operation of cleansing ceremonially, by removing any pollution or defilement.
  • (n.) A cleansing from guilt or the pollution of sin; the extinction of sinful desires, appetites, and inclinations.

Example Sentences:

  • (1) During enzyme purification two nucleases were identified.
  • (2) Change of steps in achieved just by varying the reaction conditions without any product purification.
  • (3) Further purification of ZAB by filtration through Sephadex G-100 gave a preparation (ZAB2) which contained the common antigen as shown by the cross-reactivity of anti-ZAB2 rat serum with seven stains of N. gonorrhoeae.
  • (4) Stable factor-dependent B-cell hybridomas were used to monitor the purification of the growth factor from the supernatant of a clonotypically stimulated mouse helper T-cell clone.
  • (5) After immunoadsorbent purification, the final step in a purification procedure similar to that adopted for colon cancer CEA, two main molecular species were identified: 1) Material identical with colon cancer CEA with respect to molecular size, PCA solubility, ability to bind to Con A, and most important the ability to bind to specific monkey anti-CEA serum.
  • (6) Currently there are no IOC approved definitive tests for these hormones but highly specific immunoassays combined with suitable purification techniques may be sufficient to warrant IOC approval.
  • (7) A rapid method is described for the purification and analysis of synthetic oligonucleotides, based on reversed-phase high-performance liquid chromatography.
  • (8) The influence of exogenous mitogens (RFG, TGF beta 1 and insulin) and autocrine factor (at different step of purification) on the growth of Morris hepatoma 7777 (MH) cells was estimated by both methods.
  • (9) In a previous publication the purification and properties of two protein kinases (KI and KII) from a soluble fraction of bovine corpus luteum and the stimulation of the latter fol.
  • (10) for 48 h followed by Leydig cell isolation and purification resulted in a decrease in the maxima of hCG-induced cAMP accumulation and testosterone production by approximately 70% and approximately 55%, respectively, when compared to cells of control mice.
  • (11) These plasmids allow expression of native or truncated forms of the enzyme and easy purification of the products.
  • (12) The enzyme extracted from strains containing the recombinant plasmid was identical to N. crassa catabolic dehydroquinase by the criteria of heat stability, ammonium sulfate fractionation, immunological crossreactivity, molecular weight, and purification characteristics.
  • (13) Three triacetinases (A, B and C) were shown to undergo reciprocal conversions under storage and during some purification procedures (effect of pH, ionic strength, ion-exchange chromatography, concentration, lyophilization, etc.).
  • (14) Sindbis virus nucleocapsids were isolated from mature virions by a two-step purification method.
  • (15) The major scrapie prion protein, designated PrP 27-30, exhibited both charge and size heterogeneity after purification from infected hamster brains.
  • (16) We have used this procedure successfully during the purification of epidermal glycoproteins.
  • (17) The purification and concentration of these viruses in their monomeric forms is hazardous when conventional "tube" rotors are used since they invariably result in dissociation and aggregation of the virus particles.
  • (18) These methods can be applied to the purification and characterization of the as yet undefined secretory and circulating forms of PTHrP.
  • (19) The possibility that mammalian DNA topoisomerase II is an intracellular target which mediates drug-induced DNA breaks is supported by the following studies using 4'-(9-acridinylamino)methane-sulfon-m-anisidide (m-AMSA): (a) a single m-AMSA-dependent DNA cleavage activity copurified with calf thymus DNA topoisomerase II activity at all chromatographic steps of the enzyme purification; (b) m-AMSA-induced DNA cleavage by this purified activity resulted in the covalent attachment of protein to the 5'-ends of the DNA via a tyrosyl phosphate bond.
  • (20) These experiments may provide the basis for the expanded use of immobilized lectins for purification and characterization of hydrolases and other glycoproteins.