(n.) The quality or state of being unable; lack of ability; want of sufficient power, strength, resources, or capacity.
Example Sentences:
(1) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(2) The mother in Arthur Ransome's children's classic, Swallows and Amazons, is something of a cipher, but her inability to make basic decisions does mean she receives one of the finest telegrams in all literature.
(3) Major limitations of the conventional sperm penetration assay are the inability to assess several aspects of sperm function (zona binding and penetration) and the absence of human ovulatory products known to influence fertilization.
(4) While cells that were treated with antibody were unable to aggregate because of the inability to destroy cAMP, they aggregated normally when washed free of antibody.
(5) Cessation of coital activity was associated with specified types of stress between 65 and 70 years of age in the subgroup of men who had stopped due to inability; six out of eight reported stress against five out of 20 in the C group, P less than 0.05.
(6) The patient was referred to the podiatry department because of continued discomfort and the inability to run.
(7) Localization of the receptor binding domain within the C-terminal region of PA was suggested by the inability of the monoclonal antibodies 3B6 and 14B7 to recognize the recombinant proteins expressed by C-terminal deletions of the pag gene.
(8) The most frequent presentation is the inability to retain the external prosthesis.
(9) Fibroblastic cells were characterized by their spindle shape, content of a mucopolysaccharide, their relative inability to synthesize infectious influenza virus, and production of a cell-associated noninfectious hemagglutinin.
(10) The determination of circulating biologically active PTH in the rat has been difficult due at least in part to the inability to develop an antibody suitable for RIA of rat PTH.
(11) We now provide evidence strongly suggesting that the primary defect in Lec8 and Clone 13 cells is their inability to translocate UDP-galactose into the lumen of the Golgi apparatus.
(12) A major limitation of 3-D CT is its inability to reconstruct the pathology of soft tissues with the same fidelity afforded bony structures.
(13) The researchers suggested that the inability to establish relationships may be due to a function of methods, sample size, or a reflection of a different population.
(14) First, chains are constrained by their inability to penetrate the boundary.
(15) The sequence of the murine protein differs from that of the human protein in 10% of residues, and it may be presumed that some of these differences are responsible for the inability of gibbon ape leukemia virus to infect mouse fibroblasts.
(16) Thus, children's early difficulty in reading may be one sign of a general inability to selectively attend to the parts of any perceptual wholes.
(17) As there is evidence for the relative inability of infants to synthesize taurine, this nitrogen compound has to be wholly supplied by the mother during pregnancy and by diet after birth, particularly for the prematures who have to constitute appreciable reserves in their tissues.
(18) The inability of these young smokers to enhance their mucus clearance by cough suggests a change in the mucociliary apparatus from normal.
(19) An additional 17 patients considered highly in need of treatment met criteria for commitment based on inability to care for self, but most were hospitalized voluntarily.
(20) Phosphoglyceride and triacylglycerol biosynthesis in glycerol kinase deficiency fibroblasts is not diminished by the inability to use glycerol as a precursor of glycerol 3-phosphate.
Insomnia
Definition:
(n.) Want of sleep; inability to sleep; wakefulness; sleeplessness.
Example Sentences:
(1) To the remaining patients who suffered from severe insomnia, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one (chlordesmethyldiazepam, 2 mg orally) was administered for 7 consecutive evenings.
(2) The features of benzodiazepine withdrawal in the elderly may differ from those seen in young patients; withdrawal symptoms include confusion and disorientation which often does not precipitate milder reactions such as anxiety, insomnia and perceptual changes.
(3) Bilateral destruction or functional elimination of either hypnogenic region is followed by increased vigilance and insomnia.
(4) Since she was 25-year-old, she had had insomnia which accompanied by choked feelings, palpitations, clumsiness of hands and anxiety.
(5) Except for insomnia in women, which was most prevalent in December, no significant relationship between month of survey and any of the 3 symptoms were found.
(6) Since chronic insomniac patients tend to internalize their feelings, which leads to increased psychologic arousal and insomnia, the therapist must consistently re-orient the patient toward awareness and expression of feeling.
(7) These drugs treat reactive anxiety, insomnia, claustrophobia, and panic disorder.
(8) So should you bin the sleeping pills or take a couple to break the cycle of insomnia?
(9) The following differential signs were underlined: initial symptoms, such as rudimentary cenesthopathia, stable insomnia, etc., preceding the formation of delusions; appearance of episodic exacerbations in the form of short-time acute paranoiac states; a combination of paranoiac delusion with stable phasic affective disorders; unusual possession of delusional patients expressed in bizarre delusional behaviour, etc.
(10) Dizziness in three with insomnia and vomiting in one patient complicated the treatment.
(11) With the Extracted Criteria, initial insomnia, early waking, anorexia, weight loss, loss of libido, and worsened mood in the morning were all significantly more common in melancholia than in non-melancholic depression, while increased appetite was more common in non-melancholia.
(12) Half-life does appear to be an important determinant of the presence or absence of rebound insomnia.
(13) A permanent and direct relationship can be elucidated between the duration of insomnia and the depth of paranoid.
(14) No rebound insomnia was evident during a 7 day post-treatment withdrawal period for either zopiclone or nitrazepam.
(15) These data suggest an active role of limbic mu and delta receptors in the generation of arousal and insomnia related to sleep deprivation induced stress.
(16) Somnolence, hypotonia, weight gain, excitation, and insomnia were the most common problems at the beginning of the study and were usually transient.
(17) In women, poor outcome was associated with multiple depressive symptoms, depression diagnosed previous to this study, not living alone, low social participation, low self-perceived health, diurnal variation of symptoms, and the occurrence of initial insomnia, loss of libido, and hypochondriacal and compulsive symptoms.
(18) The lower incidence of insomnia is interesting in view of zotepine's clinical activating effects.
(19) The treatment for insomnia often involves a combination of pharmacotherapy, behavioral and short-term psychotherapy, and sleep hygiene guidelines.
(20) Studies in rats, normal human subjects, and subjects with mild insomnia all demonstrate that L-tryptophan reduces sleep latency.