(a.) Not accessible; not to be reached, obtained, or approached; as, an inaccessible rock, fortress, document, prince, etc.
Example Sentences:
(1) Two-thirds of the cytoplasmic water is inaccessible to sucrose and is designated c2.
(2) These are usually located in the intracranial part of the vertebral artery and less frequently in the lower basilar artery, and are therefore inaccessible to prophylactic vascular surgery.
(3) Unfortunately, transitional cell carcinoma may involve other regions of the prostate that are inaccessible by cystoscopy.
(4) Acquisition of Ab inaccessibility occurred very efficiently in this cell-free system (approximately 50% of total cell-associated 125I-BSST became inaccessible) and could be inhibited by anti-clathrin mAbs and by antibodies directed against the cytoplasmic domain of the transferrin-receptor.
(5) Inaccessibility of essential health information to the women most affected, and the physical as well as economic and sociocultural distance separating health services from the vast majority of women, are only part of the problem.
(6) It also provides important details about potential surgical routes to this relatively inaccessible region.
(7) Bypass of surgically inaccessible stenoses or occlusions appears to be a logical technique to prevent future stroke but there is much uncertainty about the clinical indications for surgery and even the natural history of the lesions being bypassed.
(8) In 2019, the long-awaited Crossrail project is due to open, but up until a few weeks ago, seven of the 38 stations on the route were set to remain inaccessible.
(9) Because of the mild and focal nature of the inflammatory infiltrates and involvement of regions inaccessible to the bioptome, sampling error contributes appreciably to false-negative results in endomyocardial biopsy tissue from patients with myocarditis.
(10) The dissociation constant of ATP from the unligated enzyme, a constant that has previously been experimentally inaccessible, has been measured for wild-type and several mutant enzymes.
(11) We must urgently tackle this culture of inaccessible politics.
(12) The problems faced in the prevention and control of malaria include problems associated with the opening of land for agriculture, mobility of the aborigines of Peninsular Malaysia (Orang Asli) and inaccessibility of malaria problem areas.
(13) However, in less than 15 sec, LTB4-treated PMN lose the ability to respond further to LTB4; decrease the affinity and number of high affinity receptors available for binding LTB4; sequester LTB4 in plasmalemma-associated sites that are inaccessible to a releasing buffer regimen; and begin internalizing LTB4.
(14) The species-specific inactivation in concluded from various lines of evidence to be ATP-site-directed and is attributed to alkylation of an amino acid residue of the rabbit enzyme which in the pig and carp enzymes is absent, inaccessible, or less reactive.
(15) Because the three major proteins of the Karp and Gilliam strains are accessible to antibody in unextracted organisms, it is possible that the exteriorly exposed epitopes of these three polypeptides are strain specific and that their common determinants are normally buried in the membrane or otherwise inaccessible.
(16) This decrease in PI-PLC sensitivity may reflect an alteration in the PI-glycan anchoring structures, or in a general membrane property, which renders the PI-anchored proteins inaccessible to the enzyme.
(17) A deficit in, or the inaccessibility of, J chain protein appears to facilitate hexamer formation.
(18) We have already introduced a vacuum drainage system, which is a special drainage system through a machine that removes water, but we cannot do anything about the climate of the Amazon.” Bastos went on to outline the problems with maintaining a pitch in such an inaccessible part of Brazil.
(19) We discuss the possibility that a shift in equilibrium between accessible and inaccessible transporters is operating.
(20) One of the physiological consequences of these interactions is that polymorphonuclear leukocytes stimulated with either chemoattractants or TNF form protected compartments at their interface with fibrinogen-coated surfaces and that elastase released into these compartments is inaccessible to protease inhibitors present in the plasma.
Unaccessible
Definition:
(a.) Inaccessible.
Example Sentences:
(1) The finding that free (3H)-NANA was markedly increased relative to its major products (3H)-HexNAc is suggestive for an impaired degradation and reutilization of (3H)-NANA due to trapping in a metabolically unaccessible pool.
(2) Several clinical trials were performed in patients with metastatic disease unaccessible to more conventional therapy of proven efficacy.
(3) The qualities are: "Unnahbarkeit" (unaccessibility), "Unzufriedenheit" (dissatisfaction), "Schwermut" (melancholy), "Trockenheit" (dryness), and "Schönheit" (beauty).
(4) It is concluded that it is safe and effective to give these antigens simultaneously and that this particular schedule lends itself for use with nomadic and other unaccessible groups of population.
(5) In two patients with unaccessible femoral and brachial arteries and one with bilateral occlusion of the femoral arteries selective left and right coronary angiography was performed by translumbar insertion of catheters using a modified catheter replacement technique.
(6) An evaluation of the chromatographic behavior of selected model proteins--thioredoxin, ubiquitin, calmodulin, lysozyme, cytochrome c, and myoglobin on immobilized transition metal ions (Co2+, Ni2+, Cu2+, and Zn2+)--allows establishment of the following facets of the histidyl side chain distribution: (i) either interior or surface; (ii) when localized on the surface, accessible or unaccessible for coordination; (iii) single or multiple; (iv) when multiple, either distant or vicinal.
(7) Internalization can lead to unaccessibility of generated H2O2 for extracellular scavengers and pH optimization for glucose oxidase activity, which provides valuable advantages for the cytotoxicity of the conjugate.
(8) The emitter is shown to be a mono-protonated phthalate unaccessible by photoexcitation.
(9) The cases with infections localized in rather unaccessible sites required double the dose and strict drainage and cleanliness.
(10) The data obtained showed that the lysine residues in positions 12, 15, 27, 43, 136, 141, 265 were entirely modified, those in positions 170, 184, 237 were partially modified, and Lys22 and Lys94 were unaccessible for the reagent.
(11) Dye molecules were adsorbed on double-stranded sequences (11--12% of the total amount of RNA in 30S-particles) and on the single-stranded parts of RNA (58--59% of 30S-particles), the rest part of RNA was unaccessible for the dye binding.
(12) In contrast, the B17-21 epitope, unaccessible by immunoblotting, is probably conformational.
(13) Trypsin treatment of mitochondria isolated from both transformed strains indicated that the fusion protein is anchored to the outer membrane and exposed to the medium while the unfused luciferase retained with the mitochondria is occluded in a compartment unaccessible to trypsin and released in the presence of detergent.
(14) Where removal of an otherwise unaccessible ventricular pacemaker electrode is considered essential the use of a Dormier basket percutaneously appears to be effective and more acceptable than surgical removal.