(1) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(2) Groups of inbred female mice of strains CBA or C3H were infected genitally with a pathogenic human strain of Chlamydia trachomatis (N.I.1, serovar F) known to produce salpingitis and infertility in mice.
(3) An N-acetylation polymorphism is described that is expressed toward arylamine carcinogens in tumor target organs of an inbred rat model.
(4) Lymphocytes of inbred mice immunized with allogenic tumour cells were labelled in vitro or in vivo by 3H-thymidine, washed out and incubated with target cells in the presence of "cold" thymidine.
(5) In the present study we screened mice from 22 different inbred strains for potential differences in their immunological reaction to HgCl2.
(6) Using molecular probes to examine somatic cell lines and recombinant inbred and congenic strains of mice, we have re-evaluated these linkage relationships.
(7) We have investigated enhancement of pigmentation in inbred C3H- mice using tail skin as a model for testing the effects of phosphorylated DOPA (DP) and ultraviolet radiation.
(8) These results are discussed in relation to previous reports suggesting a common addiction liability for both morphine and alcohol in inbred strains of animals.
(9) Mta is determined by a maternally transmitted, extrachromosomal genetic element, so backcross mice reject skin from their inbred, homozygous paternal strain.
(10) However, rmm-1, a cis-acting laboratory-induced mutation obtained previously by mutagenesis of inbred strain C3, causes the mutant rmm-1 rDNA to be completely out-replicated by B rDNA.
(11) Inbred strain 2 and random-bred guinea pigs injected oxazolone in incomplete or complete Freund's adjuvant showed contact reactions within an hour after topical application when tested 3 weeks post-sensititization.
(12) 2 inbred brothers with brachydactyly of the index fingers and 1 case of 'achondroplasia' were also found.
(13) An analysis of these recombinant inbred strains may reveal additional mouse genes affecting atherosclerosis susceptibility.
(14) The distribution of derepression among castrated recombinant inbred strains (9 X A) indicated a close link of a locus repressing I-P-450(16 alpha) in male mice to the Rip locus on chromosome 7.
(15) The number of serotonin type 2 receptors (S2) was measured in the frontal cortex of mice belonging to 7 inbred strains using specific 3H-spiperone binding.
(16) This study provides evidence that complement activation by graft-bound alloantibody is a critical effector mechanism of hyperacute rejection in this inbred rat model.
(17) Resistance to MCA-induced lymphoma was dominant over susceptibility in all crosses tested, and in inbred strain mice MCA resistance was found to correlate with resistance to lymphoma induced by a fractionated dose of gamma irradiation.
(18) Earlier studies demonstrated that these inbred birds have normal peripheral blood T and B cell numbers; they also respond normally to allogeneic stimulation.
(19) Estimated genetic progress per generation due to within-line selection was negative in most of the traits in the inbreds but was considerably positive for the linecrosses for most of the traits.
(20) Two types of mitochondrial DNA (mtDNA) can be distinquished in an inbred strain of rats of the Wistar type.
Inbreeding
Definition:
(p. pr. & vb. n.) of Inbreed
Example Sentences:
(1) Regressional analysis of relations between loads and the level of inbreeding in the Adyg population showed the explicit interrelation between the load of autosomal-dominant diseases and the Fst correlation coefficient being 0.89.
(2) Dogs with mammary adenocarcinoma and mixed mammary cancer had similar degrees of inbreeding.
(3) Although many studies report deleterious effects of inbreeding on prereproductive mortality (death before age 20 years), such effects are usually measured in terms of genetic load, a concept much debated in the literature.
(4) This paper presents a FORTRAN IV subroutine to calculate inbreeding and kinship coefficients from pedigree information in a diploid population without self-fertilization.
(5) Experimental increase in the fraction of tolerant response was obtained by decreasing the virus dose or by phenotypic inbreeding of rodents.
(6) Fitness measures appeared linearly related to the inbreeding coefficient of the liters, with no diminution of deleterious effects through subsequent generations of inbreeding.
(7) He postulates that this greater antimeric variance could be due to a greater degree of inbreeding in the Neandertal populations.
(8) However, in the Frankfurt line at least, one of the presumed alleles is likely to be lost due to inbreeding.
(9) The increase in inter se relationship without corresponding increase in inbreeding indicates that a change in mating strategies has evolved over time.
(10) The calculated values of gamete and endogamy indices were indicative of intensive migration processes, weak isolation by distance, and minimal inbreeding.
(11) Inbreeding coefficient was estimated for Adyg population and its structure analysed: a random component contributes mostly to the inbreeding coefficient (Fst = 0.00991), non-random component of the inbreeding coefficient being Fis = 0.010009, which testifies to negative marital assortativity among Adygs.
(12) Inbreeding depression was not enough to cause large reductions of milk and fat yield of a cow with average inbreeding.
(13) The rise in inbreeding levels in the Amish over time can be uniquely contrasted with the decline in inbreeding in most areas of the world.
(14) The present inbreeding in Norway is low (alpha4 = 0-000242), approximately one-eighth of the estimated level according to the 1891 census.
(15) This is supported by the dependence established between the frequency of the cases of oligophrenia among female persons and the inbreeding coefficient for the X-linked loci.
(16) The significance of such selection models is discussed for the retention of variability in inbreeding populations with a minimum of segregational load and higher overall stability in contrast to the overdominance models.
(17) Although the finding of a preference for siblings in estrous females is counter to expectations from an inbreeding avoidance approach, this is one of a variety of findings to suggest that not all animals avoid inbreeding all of the time.
(18) Suppression of reproduction in female offspring while they remain with the extended family unit is discussed as a life-history tactic and as a possible mechanism for inbreeding avoidance.
(19) Therefore the isonymy analysis gives a misestimation of the inbreeding coefficient, depending on the prevailing form of nonrandomness.
(20) Skin grafts were exchanged between siblings from 16 inbreeding lines of rabbits.