(a.) Not dispensable; impossible to be omitted, remitted, or spared; absolutely necessary or requisite.
(a.) Not admitting dispensation; not subject to release or exemption.
(a.) Unavoidable; inevitable.
Example Sentences:
(1) She was organised, good with people, very grown up and quickly proved herself to be indispensable.
(2) The lack of any easy clinical characteristic objectivisation often prevents easy recognition and complex diagnostic investigation is therefore indispensable.
(3) Duplex and color Doppler sonography have become indispensable for evaluating the major vessels of the abdomen.
(4) The data presented here indicate that renal clearance is not indispensable for eliminating etoposide.
(5) Therefore, observance of the generally accepted withdrawal time of 10 days is indispensable.
(6) Nurses are an indispensable part of these urban health teams and, if they are not already, should start now to become involved in urban policymaking and planning and consider how their national nurses' association can individually or collaboratively support healthy city projects and national healthy city networks.
(7) It is indispensable to establish a close cooperation between the public health authorities and the private physician, and we therefore wish to sincerely thank all colleagues and Public Health Officers for their collaboration.
(8) Treasury secretary Tim Geithner called her an "exceptional talent" whose broad experience would "provide invaluable leadership for this indispensable institution at a critical time for the global economy".
(9) These changes facilitate radium therapy which remains an indispensable arm for sterilizing primary lesions.
(10) "We will take part as requested … An agreement is indispensable for Europe, and not just Europe ," UniCredit chief executive Federico Ghizzoni told reporters in Rome, according to Reuters.
(11) A careful physical examination is indispensable, and masses should be evaluated with consideration given to mobility, location, consistency, contour, and site.
(12) Using this scoring system it is possible to establish comparable groups of patients - which seems indispensable for a critical examination of various therapeutic procedures.
(13) indispensable to attain normal reaching motor functions.
(14) This case shows that new or recurrent spinal cord symptoms may be due to a mechanical deformity of the cord rather than shunt malfunction, that restricting the length of the shunt catheter which is used to decompress PTSCCs is important, and that IOSS is an indispensable tool for visualizing the changes in spinal cord morphology during shunting procedures.
(15) In 46 patients the standard series was sufficient for diagnosis of allergic occupational contact dermatitis, but in thirty three cases it was indispensable to test them with additional subsances.
(16) That is a sign for increasing waste of reciprocal control of adrenal gland and liver, that is indispensable to maintenance of corticosteroid hemostasis.
(17) In order to establish whether the periaqueductal gray (PAG) is indispensible for peptide-induced excessive grooming, lesions were placed in the dorsal part of this structure.
(18) Polymodal pattern of regulation of this parameter is suggested which includes indispensable participation of both thermal and non-thermal factors of selection.
(19) Play is indispensable to human progress and good for individuals.
(20) Ultrasound is an indispensable tool for preliminary diagnosis ('filter function'), during treatment ('monitoring function') and in the followup examinations ('follow-up function') after shock wave lithotripsy of gallstones.
Intrinsic
Definition:
(a.) Inward; internal; hence, true; genuine; real; essential; inherent; not merely apparent or accidental; -- opposed to extrinsic; as, the intrinsic value of gold or silver; the intrinsic merit of an action; the intrinsic worth or goodness of a person.
(a.) Included wholly within an organ or limb, as certain groups of muscles; -- opposed to extrinsic.
(n.) A genuine quality.
Example Sentences:
(1) Although each of palate and limb is concurrently susceptible to epigenetic regulation, their differential intrinsic genomic capabilities appear to have been uncoupled.
(2) For enrolled nurses an increase in "Intrinsic Job Satisfaction" was less well maintained and no differences were found over time on "Patient Focus".
(3) The data indicate that adult neurons with an intrinsic ability to regenerate axons can respond to substances with neurotrophic or neurite-promoting activities in tissue cultures.
(4) Relative to the perceived severity of their asthma, both Maoris and Pacific Islanders lost more time from work or school and used hospital services more than European asthmatics using A & E. The increased use of A & E by Maori and Pacific Island asthmatics seemed not attributable to the intrinsic severity of their asthma and was better explained by ethnic, socioeconomic and sociocultural factors.
(5) On the other hand, the injection of minute quantities of endotoxin into PbAc(2)-sensitized rats invariably resulted in disseminated intravascular coagulation, apparently via a complete activation of the intrinsic pathway.
(6) Pathological changes may, thus, be initially confined to projecting and intrinsic neurons localized in cortical and subcortical olfactory structures; arguments are advanced which favor the view that excitotoxic phenomena could be mainly responsible for the overall degenerative picture.
(7) DL 071 IT, a new potent non-selective beta-adrenergic blocking drug with intrinsic sympathomimetic activity and weak membrane stabilizing activity, was evaluated alone and in comparison with oxprenolol, in six volunteers, at rest and during an exercise test.
(8) These results suggest that the majority of D1 and D2 receptors in prefrontal and anterior cingulate cortices are located postsynaptically on neurons intrinsic to the cortex.
(9) Intrinsic bending of the 527-bp fragment (bend center approximately at bp 240) was represented as a composite of at least two components located near bp 170 and near bp 260.
(10) This technique is sensitive to the optical anisotropy within the muscle, including that due to intrinsic properties of the protein molecules as well as that due to the regular arrangement of proteins in the surrounding medium.
(11) Using the results of a first evaluation made in 1989, a series of recommendations were made to reduce the prescription of drugs with a low intrinsic value (LIV).
(12) Urinary excretion of (60)Co radioactivity in pernicious anemia patients after oral administration of (60)Co-vitamin B(12) bound to freshly prepared (125)I-labeled IF was similar to that obtained with noniodinated intrinsic factor.
(13) A plantar approach, implanting into the deep layer of intrinsics, was used.
(14) These data suggest that in terms of prolactin release, prolactin producing tumour cells are intrinsically refractory to hypo thalamic dopaminergic signals.
(15) Its isoelectric point is at pH 11.1 and intrinsic viscosity is 0.038 dl g-1 in 0.2 M NaCl.
(16) Within the restriction provided by surface area and volume, the intrinsic properties of the membrane and cytoplasm determine the deformability characteristics of the red cell.
(17) Quenching of intrinsic fluorescence of (Ca2+-Mg2+)-ATPase by acrylamide, performed in the presence of Ca2+, gave evidence for a single class of tryptophan residues with Stern-Volmer constant (KSV) of 10 M-1.
(18) This formalism allows resolution of the intrinsic protein folding-unfolding parameters (enthalpy, entropy, and heat capacity changes) as well as the ligand interaction parameters (binding stoichiometry, enthalpy, entropy, and heat capacity changes).
(19) This provides a compelling argument that the protein kinase function of p37mos is an intrinsic property of the protein.
(20) These data support the conclusion that there are mechanisms intrinsic to each tissue which exert a degree of control during growth over its chemical composition; therefore, growth itself can be considered an intrinsic regulatory mechanism.