What's the difference between indoles and innate?

Indoles


Definition:

  • (n.) Natural disposition; natural quality or abilities.

Example Sentences:

  • (1) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
  • (2) This derivative also allowed sensitive detection and measurement of indole-3-pyruvate in the picogram range using a gas chromatograph with an electron capture detector.
  • (3) In addition, it has excellent antibacterial activity against indole-positive Proteus strains against which conventional Cephalosporins are ineffective.
  • (4) These findings imply that smooth muscle replication in advanced plaques is indolent and raise the possibility of a role for proliferating leukocytes.
  • (5) Mitomycin C extravasation produces a painful indolent ulcer that does not have any tendency to heal.
  • (6) Among the indoles tested only 6-chloromelatonin, melatonin and N-acetylserotonin had significant affinities to the [125I]iodomelatonin binding site.
  • (7) Using thin layer chromatography on fluorescent silica gel plates, 5 indoles were identified and 6 unknown substances isolated from the pineal incubate and from both extracts.
  • (8) It was also found that the levels of s-dTK in the progressive stage were much higher than those in the indolent stage.
  • (9) Cyclobutadipyrimidines (pyrimidine dimers) undergo splitting that is photosensitized by indole derivatives.
  • (10) This series of compounds includes [R-(R*,R*)]-4-[[2-[[3-(1H-indol-3-yl)-2-methyl-1-oxo-2- [[(tricyclo[3.3.1.1] dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]- 4-oxobutanoic acid (CI-988, 1, Figure 1), the first rationally designed non-peptide antagonist of a neuropeptide receptor.
  • (11) Eight of the nine (88.9%) Proteus vulgaris isolates gave a positive spot indole test; one (11.1%) gave a negative result.
  • (12) 15 human tumour cell lines (lung, breast and colon) have been evaluated for their sensitivity to the quinone based anti-cancer drugs Mitomycin C, Porfiromycin, and EO9 (3-hydroxymethyl-5-aziridinyl-1-methyl-2-(IH-indole-4,7-dione)prop-beta- en-alpha-ol).
  • (13) The fluorogenic beta-D-Glucuronidase test, together with an Indol-capillary test for rapid identification of E. coli, were proved with 60 toxinogenic, 335 nontoxinogenic wild-type strains, and 87 other gram-negative isolates from food.
  • (14) Enzymatic production of L-tryptophan from DL-serine and indole by a coupled reaction of tryptophan synthase and amino acid racemase was studied.
  • (15) It inhibited some Enterobacter and indole-positive Proteus, but it was less active against these later species than was cefamandole, cefuroxime, or cefoxitin.
  • (16) An hydroxyl group in the 5 position of the indole nucleus, sterically unencumbered by hydroxyls in neighboing positions, is essential.
  • (17) We now report a second case with similar features of chronic recurrent indolent inflammatory skin lesions, nondiagnostic skin biopsies, and failure to respond to antibiotics.
  • (18) In this study, the roots of Tabernaemontana heyneana Wall were examined and the isolation and identification of additional indole alkaloids and some pharmacological properties of coronaridine are described.
  • (19) In an effort to understand the mechanism by which dietary indoles inhibit chemically initiated tumorigenesis in experimental animals, we have investigated the potency of 3-substituted and 1,3-disubstituted indoles on the induction of intestinal and hepatic cytochrome P-448-dependent monooxygenases in the rat.
  • (20) Low nanogram levels of tyrosine, norepinephrine, 5-hydroxyindole-3-acetic acid, tryptophan, serotonin and 6-hydroxymelatonin, and picogram levels of 5-hydroxytryptophan, 5-hydroxytryptophol, 5-methoxyindole-3-acetic acid, indole 3-acetic acid, 5-methoxytryptophol and melatonin were indicated in most of the samples.

Innate


Definition:

  • (a.) Inborn; native; natural; as, innate vigor; innate eloquence.
  • (a.) Originating in, or derived from, the constitution of the intellect, as opposed to acquired from experience; as, innate ideas. See A priori, Intuitive.
  • (a.) Joined by the base to the very tip of a filament; as, an innate anther.
  • (v. t.) To cause to exit; to call into being.

Example Sentences:

  • (1) A sequence of seven pairings of chili-flavored diet with prompt recovery from thiamine deficiency did significantly attenuate the innate aversion and may have induced a chili preference in at least one case.
  • (2) The model also lends itself to studies of the immunologic interrelationships between innate and acquired resistance to infection with schistosomes, as well as the mechanisms by which these parasites evade the host immune response.
  • (3) In a speech to Atlantic Bridge members in New York in November 2002, Fox warned "the natural desire to avoid conflict has been reinforced by an innate pacificism in many sections of western society, especially in continental Europe".
  • (4) Does he really think, like those daft gender essentialists, that women are innately gentle and men are big brutes out for a ruck?
  • (5) It is concluded that there is an increased activity of Na-K pump in the cultured MC from SHR, and that this abnormality may be innate to SHR cells.
  • (6) The choice of a trainee in surgery should be based at least partially on his innate abilities, and his training should be begun at an appropriate level.
  • (7) He is an innately optimistic character as well as a clever one, and a man who needs to persuade his party not to despair.
  • (8) X-irradiation apparently did not affect the innate susceptibility cr resistance of hamsters and mice to worms.
  • (9) But he does have an innate sense of what London needs.
  • (10) In an effort to assess the innate capacity of the central visual system to specify corticocortical connectivity in the absence of retinal afferents, we examined the tangential distribution of callosal cells and terminations in posterior neocortex of congenitally anophthalmic rats.
  • (11) It was suggested that the influence of strong timing constraints was greater on the auxiliary function than on the innate function of the biceps (elbow flexor).
  • (12) The combination of interferons was effective in suppressing glioblastoma growth both in cultures displaying relative sensitivity and those exhibiting innate resistance to either or both types of interferon when employed alone.
  • (13) Such a mechanism could play a key role in coordinating the humoral, cell-mediated, and innate responses of the immune system.
  • (14) 1, 2, 3, 6) would be attained at an earlier age and no plateau would be observed in contrast to Israeli non-clinical school children whose right-left reading-writing habits are in a direction opposite to the assumed innate drawing tendency, were confirmed at significant levels of confidence.
  • (15) Microcirculatory vascular bed was sampled from dura mater of children under 1 year (healthy and with intracranial hypertension due to innate hydrocephalus) and stained with hematoxylin-eosin.
  • (16) Trematode diseases have remained the same, but the tools (1) to exploit the innate ability of cells to replicate and produce biological products upon demand, (2) to manipulate the genetic makeup of an organism, (3) and to biologically or synthetically manufacture peptides have provided scientists with new reagents for diagnosing, treating, preventing and controlling trematode diseases.
  • (17) The correlation coefficient (Spearman's) for EC50 versus potency at the frog neuromuscular junction was -0.73, indicating innate differences between Torpedo and frog receptors.
  • (18) It is provisionally suggested that enhancement of the perseveration represents an innate response to stressful stimuli, but as animals learn mastery over the response contingencies, the persistence in adopting such a response strategy wanes.
  • (19) The neurobehavioral characteristics of the Tokai High-Avoider (THA) rats, which had an innate high-avoidance ability, were clarified by comparing with the Wistar rats from which the THA rat strain had been derived.
  • (20) The purpose of this assay was to assess the innate proliferative potential and microenvironmental influences on the ability to repopulate.

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