What's the difference between indoles and unalterable?

Indoles


Definition:

  • (n.) Natural disposition; natural quality or abilities.

Example Sentences:

  • (1) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
  • (2) This derivative also allowed sensitive detection and measurement of indole-3-pyruvate in the picogram range using a gas chromatograph with an electron capture detector.
  • (3) In addition, it has excellent antibacterial activity against indole-positive Proteus strains against which conventional Cephalosporins are ineffective.
  • (4) These findings imply that smooth muscle replication in advanced plaques is indolent and raise the possibility of a role for proliferating leukocytes.
  • (5) Mitomycin C extravasation produces a painful indolent ulcer that does not have any tendency to heal.
  • (6) Among the indoles tested only 6-chloromelatonin, melatonin and N-acetylserotonin had significant affinities to the [125I]iodomelatonin binding site.
  • (7) Using thin layer chromatography on fluorescent silica gel plates, 5 indoles were identified and 6 unknown substances isolated from the pineal incubate and from both extracts.
  • (8) It was also found that the levels of s-dTK in the progressive stage were much higher than those in the indolent stage.
  • (9) Cyclobutadipyrimidines (pyrimidine dimers) undergo splitting that is photosensitized by indole derivatives.
  • (10) This series of compounds includes [R-(R*,R*)]-4-[[2-[[3-(1H-indol-3-yl)-2-methyl-1-oxo-2- [[(tricyclo[3.3.1.1] dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]- 4-oxobutanoic acid (CI-988, 1, Figure 1), the first rationally designed non-peptide antagonist of a neuropeptide receptor.
  • (11) Eight of the nine (88.9%) Proteus vulgaris isolates gave a positive spot indole test; one (11.1%) gave a negative result.
  • (12) 15 human tumour cell lines (lung, breast and colon) have been evaluated for their sensitivity to the quinone based anti-cancer drugs Mitomycin C, Porfiromycin, and EO9 (3-hydroxymethyl-5-aziridinyl-1-methyl-2-(IH-indole-4,7-dione)prop-beta- en-alpha-ol).
  • (13) The fluorogenic beta-D-Glucuronidase test, together with an Indol-capillary test for rapid identification of E. coli, were proved with 60 toxinogenic, 335 nontoxinogenic wild-type strains, and 87 other gram-negative isolates from food.
  • (14) Enzymatic production of L-tryptophan from DL-serine and indole by a coupled reaction of tryptophan synthase and amino acid racemase was studied.
  • (15) It inhibited some Enterobacter and indole-positive Proteus, but it was less active against these later species than was cefamandole, cefuroxime, or cefoxitin.
  • (16) An hydroxyl group in the 5 position of the indole nucleus, sterically unencumbered by hydroxyls in neighboing positions, is essential.
  • (17) We now report a second case with similar features of chronic recurrent indolent inflammatory skin lesions, nondiagnostic skin biopsies, and failure to respond to antibiotics.
  • (18) In this study, the roots of Tabernaemontana heyneana Wall were examined and the isolation and identification of additional indole alkaloids and some pharmacological properties of coronaridine are described.
  • (19) In an effort to understand the mechanism by which dietary indoles inhibit chemically initiated tumorigenesis in experimental animals, we have investigated the potency of 3-substituted and 1,3-disubstituted indoles on the induction of intestinal and hepatic cytochrome P-448-dependent monooxygenases in the rat.
  • (20) Low nanogram levels of tyrosine, norepinephrine, 5-hydroxyindole-3-acetic acid, tryptophan, serotonin and 6-hydroxymelatonin, and picogram levels of 5-hydroxytryptophan, 5-hydroxytryptophol, 5-methoxyindole-3-acetic acid, indole 3-acetic acid, 5-methoxytryptophol and melatonin were indicated in most of the samples.

Unalterable


Definition:

Example Sentences:

  • (1) As Nick Bostrom, the head of the Future of Humanity Institute at the University of Oxford and a leading transhumanist thinker puts it, transhumanism "challenges the premise that the human condition is and will remain essentially unalterable".
  • (2) After suppression of prolactin, statistically signific1nt circadian rhythms in PC and PA have been detected with a moderate decrease of PA concentration, while the PC level remained unalterated.
  • (3) The following resolutions were adopted:– "That we, a monster meeting of the Orangemen of Newtownards and of the surrounding districts, recognise, with gratitude, the exertions of our brethren in time past, and declare our unalterable determination to stand or fall by the principles of our Order in defence of Her Majesty the Queen and of the British Constitution.
  • (4) General distrust of genetic methodologies as well as the belief that genic disorders are unalterable appear to be salient factors in explaining the neglect of those areas by social scientists.
  • (5) Unalterable numerical and alphabetical symbols have been developed to apply a registration number to the animal.
  • (6) Oxygen consumption is usually considered to be predictable and unalterable at a fixed work intensity.
  • (7) We conclude that the preliminary diagnosis is frequently sufficiently certain to be unalterable by US.
  • (8) Who have that hunger for something permanent and unalterable?
  • (9) Comparison of the spermiograms of unalterably vasectomized men with findings from additional rinsings with physiological saline solution and nitrofurantoin showed that the instillation of the vas deferens leads to a swift, mechanically dependent, emptying of the distal sperm depot.
  • (10) Most of the toxicity is due to an indirect effect developed with unalterable electrodes in the presence of chlorides in the medium.
  • (11) He was an open and unsophisticated operator, whose chief characteristic was an unalterable commitment to his cause.
  • (12) At the beginning of a comprehensive and systematic therapy the panorama X-ray photograph is an unalterable requirement.
  • (13) If he fails to do this, his features become frozen and unalterable, like the Person, the mask of the classic Greek theatre.
  • (14) Analysis of the virus specific proteins by polyacrylamide gel electrophoresis revealed that the synthesis of G1 was unalterable, and N was stimulated.
  • (15) Mental retardation is the major unalterable cause for failure to develop independence; some lesser emotional causes can be modified by encouragement.
  • (16) In this manner, newly found patients can be treated prophylactically before unalterable morbidity or mortality occurs.
  • (17) Although intrinsic, unalterable defects occur in the aging immune system and nonspecific host defenses, there are factors that physician and patient can concentrate on to reduce the risk of infection.
  • (18) This review identifies 10 unalterable, 6 conditionally alterable and 9 treatable characteristics which were found to be associated with an elevated risk.
  • (19) When the dilemma is unalterable, explaining this insoluble conflict-hives phenomenon to the patient will ameliorate symptoms.
  • (20) R56865 1 microM reduced the increase in resting tension produced by ouabain 300 microM and left unalterated the inotropic effect evoked by ouabain 3 and 300 microM that was reduced by higher concentrations (3 and 6 microM) of R56865.

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