(a.) Not to be subdued; untamable; invincible; as, an indomitable will, courage, animal.
Example Sentences:
(1) If Deng is a 21st-century Becky Sharp, we should recall that for all her cynicism, Thackeray's heroine also possessed an indomitable spirit.
(2) He speaks admiringly of the hot streak and indomitable desire that is shared by Suárez and Sánchez.
(3) The ideal Isolde is flame-haired, fiery, indomitable yet vulnerable, stern yet tender, and a standout dramatic soprano.
(4) The state government of Haryana said it would honour the girls’ “indomitable courage” .
(5) Just as an unbeaten run stretching back to Boxing Day could forge the same sort of indomitable team spirit that Leicester’s remarkable escape from relegation last season instilled in the King Power dressing room before Claudio Ranieri even arrived.
(6) Dean Kiely [a former Charlton goalkeeper] was always an inspiration to me because he didn’t get to the Premier League until he was 29.” Elliot’s mission is to imbue his team-mates with similarly indomitable spirit.
(7) My students understand the new media reality that has scared the once-indomitable Murdoch.
(8) That's an important crack in the NRA's seemingly indomitable public stance, and a sign that even this formidable lobby group does not stand above democratic accountability.
(9) Released 25 April Rio 2 Facebook Twitter Pinterest Well, it's hardly set on location, but if anything's going to get you buzzing for a trip to Brazil, it's this indomitable trio of CGI parrots.
(10) Fuchs bristles at that suggestion and makes an interesting analogy with a French comic book series and the indomitable Gauls fending off Roman occupation to explain Leicester’s mindset.
(11) The poorer classes seem to be getting some kind of vicarious pleasure from thinking: ‘I’m facing difficulties by standing in a queue, but the rich people who acquired wealth by dubious means, all their black money is gone.’” Whether these same people feel the pain was worth it, once money starts flowing again, will decide the fate of India’s seemingly indomitable prime minister.
(12) This, and other experiences at that time, made me even more determined to continue to show practical solidarity with the Eritreans who were demonstrating the indomitable spirit, which had, for years, enabled them to fight poverty, famine, and armed Ethiopian aggression.
(13) Now, I am in my 65th year with a teenage daughter still at home, and a mother in her 90th year who has a fragile independence boosted by an indomitable spirit, living 70 miles away.
(14) This is not the first time that financial concerns have affected the Indomitable Lions’s preparations for a World Cup.
(15) But the usually indomitable businessman admits he occasionally feels overwhelmed.
(16) But it would be surprising, when they are identified, if the great writer was not to be reburied in a place of honour so that admirers of the indomitable Knight of the Sad Countenance could pay their respects.
(17) Senator Charles Schumer called the crash “a massive and heartbreaking loss for this community.” “It deeply saddens me that Rochester has now lost two of its most indomitable, industrious visionaries,” Schumer said.
(18) Shawcross, for so long a formidable centre‑back who personified Stoke’s refusal to bow to supposed superiors, has not been his indomitable self since being afflicted by back trouble last year.
(19) In the Wimbledon final, Murray had taken an early advantage and then been hauled back, but here he was indomitable, matching everything Federer could throw at him and saving six break points.
(20) But while she might seem indomitable, Guillem knows perfectly well that her body will eventually let her down, and she has enough self-awareness to predict that she will suffer miserably when it does.
Unsurmountable
Definition:
(a.) Insurmountable.
Example Sentences:
(1) The increase in carcinoid tumour incidence observed in rats and mice after loxtidine treatment was probably related to the prolonged achlorhydria produced by this potent unsurmountable histamine H2-receptor antagonist.
(2) Flurbiprofen antagonized the response to exogenously applied ATP in an unsurmountable manner, but not that to carbachol.
(3) The very late occurrence of gastric carcinoids in a life-span carcinogenicity study with loxtidine in the rat might have resulted from continuous achlorhydria induced by this long-acting unsurmountable histamine H2-antagonist.
(4) Even though LSD behaved as a partial agonist and BOL as a pure antagonist, both drugs blocked the effect of serotonin in an unsurmountable manner, i.e., increasing concentrations of serotonin could not overcome the blocking effect of LSD or BOL.
(5) However, at concentrations below those required to produce hyperpolarization, both compounds acted as unsurmountable antagonists of 5-HT-induced hyperpolarization.
(6) The results suggest that the unsurmountable blockade of NMDA responses by DNQX and CNQX reflects an antagonist effect mediated at the allosterically linked strychnine-insensitive glycine receptor.
(7) However, in contrast to the situation described with methysergide, ritanserin and LY 53857 in several 5-HT2 receptor models, none of these antagonists acted in a non-competitive or unsurmountable fashion at 5-HT1C receptors.
(8) These results support the hypothesis that the late formation of gastric carcinoids in rats receiving loxtidine is a consequence of persistent achlorhydria caused by unsurmountable blockade of parietal cell H2-receptors.
(9) Lysergic acid diethylamide (LSD) and its structural analogue 2-bromo-lysergic acid diethylamide (BOL) act as unsurmountable antagonists of serotonin-elicited contractions in smooth muscle preparations.
(10) Metergoline and six other 5-HT antagonists acted as potent unsurmountable antagonists, only (-)-propranolol acted competitively (pA2 = 6.5).
(11) With type-II diabetics it is an unsurmounted feeling of anxiety and guilt which makes patients break off their interhuman relations and leads, in most cases, to obesity and, eventually, to the manifestation of the disease.
(12) At relatively high concentrations of the drug a slowing of aggregation and shape change to U-44619 was seen and an unsurmountable antagonism became apparent.
(13) Apart from quantitative differences, famotidine differed from the other compounds, since it caused a competitive antagonism only at low concentrations and an unsurmountable antagonism at higher concentrations.
(14) However, in human platelet-rich plasma (PRP) they produce an unsurmountable block of aggregation induced by a wide range of agents (ADP, platelet-activating factor, thrombin); this inhibitory profile is typical of that seen with either prostaglandin I2 (PGI2) or PGD2.
(15) The antagonism of responses to NMDA was unsurmountable and mediated via an antagonist action at the allosterically-linked strychnine-insensitive glycine site.
(16) Ranitidine and loxtidine had qualitatively different inhibitory effects on acid secretion, ranitidine being a competitive antagonist of histamine even at high concentrations, whereas the effect of loxtidine on both preparations was unsurmountable at relatively low concentrations.
(17) The effect of histamine was competitively antagonized by ranitidine (pA2 = 6.78) in normal solutions; conversely in 1.2 mM Ca2+, the antagonism by ranitidine became unsurmountable.
(18) Methysergide antagonized unsurmountably 5-HT-induced contractions by reducing maximum effects to 25% (coronary artery: pIC50, 9.8) and 60% (tail artery: pIC80, 9.0).
(19) The most parsimonious interpretation of these results is that unsurmountable antagonism reflects prolonged occupancy of the receptor by slowly reversible antagonists.
(20) Lysergic acid diethylamide (LSD) antagonizes the actions of 5-HT in a manner which progresses from surmountability to unsurmountability of the blockade depending on the concentration of LSD.