(v. t.) To make hard; as, extreme heat indurates clay; some fossils are indurated by exposure to the air.
(v. t.) To make unfeeling; to deprive of sensibility; to render obdurate.
(v. i.) To grow hard; to harden, or become hard; as, clay indurates by drying, and by heat.
Example Sentences:
(1) Phaso-contrast and interference microscopy investigations revealed in the damaged cells an induration of the sarcoplasmic matrix due to an increase in the dry matter concentration.
(2) The indurations from immediate and delayed hypersensitivity reactions were readily distinguishable, but the hyperthermic responses appeared to contain elements of both immediate and delayed hypersensitivity.
(3) This feature of ILC may also help explain why tumors may be palpable as areas of vague induration or thickening rather than as discrete masses.
(4) Since therapy performed by means of the moving head technique had beneficial effect on chronic prostatitis, plastic induration of the penis and the accompanying sexual potency disturbance, the method is recommended for use.
(5) Such a treatment augmented erythematous delayed reactions in animals immunized with BGG in CFA, but abolished induration at the reaction sites.
(6) While most of the clinical features--including diffuse mucosal inflammation, indurative edema, rash, and lymphadenopathy--are self-limiting, coronary artery aneurysms and the possibility of thrombotic occlusion occurs in up to 20% of children.
(7) We describe 2 patients who presented with chronic painful indurated swelling of one lower limb, thought at the time of referral to be due to chronic venous insufficiency.
(8) In the early postoperative period within an observation period from 3 to 19 months the characteristic and rather common complications in patients operated for hydrocele did not occur (hematocele, chylomas, which are mostly of ex vacuo type because of impaired blood supply and lymph system of the scrotum, abscesses, indurations of the scrotal and testicular tissues, relapses of the hydrocele, etc).
(9) Distal areas in systemic sclerosis (scleroderma), such as the dorsal skin of the hand are more frequently involved and more indurated than proximal areas.
(10) Clinical signs included lesions, indurations, and enlargement of lymph nodes.
(11) The precise basis of induration has not been established, although activation of the clotting system with consequent fibrin deposition has been clearly implicated.
(12) When IL-1 was injected intradermally into the backs of rabbits, the injection sites became indurated, erythematous, and warm to the touch after 4 hrs and annular lesions much like those of erythema chronicum migrans were seen in some animals after 24 hrs.
(13) In contrast to epicutaneous spongiotic contact dermatitis, HLA-DR was only seen on skin appendages and nearby basal keratinocytes in indurated tissue reactions with the exception of the reactions with focal basal cell layer disruption and an indurated patch test performed one week post angry back syndrome.
(14) A 52-year-old woman who had undergone an intrapleural sponge plombage operation because of tuberculosis, and had since shown an uneventful medical history for 35 years, was referred with a complaint of back skin induration over the previous surgical scar.
(15) The prevalence of tuberculous infection in a population is generally estimated from calculating the proportion of tested individuals who react with at least 10 mm of induration to 5 TU of PPD-S tuberculin.
(16) After 16 months, one of the two infected ewes suffered from indurative lymphocytic mastitis.
(17) In the guinea pigs an intradermal dose of PHA-P produced erythema and induration with a maximal response at 24 hours after the injection.
(18) Anergy, defined as no induration to any of four intradermal antigens, was present in 12%.
(19) Either the palpation method or the ball-point pen technique may be used to measure induration that results from TB skin testing.
(20) Similar, but less severe changes were seen at the site of skin tests on BCG-vaccinated subjects who were 'negative' by conventional criteria of measurement of dermal induration and they became greatly exaggerated after successful re-vaccination.
Obdurate
Definition:
(a.) Hardened in feelings, esp. against moral or mollifying influences; unyielding; hard-hearted; stubbornly wicked.
(a.) Hard; harsh; rugged; rough; intractable.
(v. t.) To harden.
Example Sentences:
(1) The system is not an obdurate one-man rule, but a balancing of power groups, including the military, government and internal security, all have different interests and policies.
(2) Both the Coalition and Labor are obdurately stuck with barbaric offshore detention policies, as though sensible, humane and politically viable alternatives are beyond them.
(3) For their part, the Israeli left accused Peres of acting as a figleaf for an obdurate Likud administration.
(4) Report on the temporary substitution of pharynx and upper oesophagus with synthetic skin substitute in case of incurable obdurating neck carcinoma.
(5) His team-mates were obdurate opponents in every respect.
(6) The fact that it was Johnson rather than Crow who had been obdurate was highlighted by the fact that TfL had all along planned to retain ticket-selling facilities at several busy stations, but, prompted by Johnson, had publicly suggested that they would all be closed.
(7) For the first time there were obvious signs of tension and, suddenly, this tough, obdurate West Bromwich side showed an attacking intent that simply had not been there earlier in the match.
(8) In the face of obdurate unreason, the president of hyper-reasonableness was forced to surrender.
(9) Underpinning the witty remarks and the textbook flippancy ("call me early, Goering dear, for I'm to be Queen of the May" was apparently Nancy's riposte to news of Diana and Unity's German adventures) though, was an absolute and obdurate self-belief; a self-possessed seriousness only partly disguised by sisterly teasing.
(10) Max from Earlsfield muses: "Admittedly terrible from Fab, a shame after 47 minutes of obdurate defence.
(11) This was a slog, a result ground out against ruggedly obdurate opposition , but Chelsea may end up gaining more satisfaction from prevailing in those awkward circumstances than from some of the more comfortable strolls they have enjoyed over a nine-match winning streak.
(12) Read more It was the third minute of stoppage time, and the cruellest of circumstances for this tough, obdurate Burnley side, when Arsenal’s possession finally paid off and the seemingly endless 20th-anniversary commemorations for Arsène Wenger were given a shot of euphoria that had not seemed like coming.
(13) Ireland were obdurate opponents but that does not fully explain the lack of quality that held back England once Frank Lampard had scored the 29th goal of his international career, 10 minutes after Shane Long's expertly taken header had given Giovanni Trapattoni's side an early lead.
(14) Russia's determination to defend wider spheres of traditional influence in the non-aligned and developing world can be seen in its obdurate refusal to penalise Syria, in the face of almost universal outrage over the crackdown there; and in its de facto defence of Iran's nuclear programme.
(15) It had needed some obdurate defending to keep the score down before Alves exchanged passes with the substitute Neymar and cut in from the right to slip his shot through Hart's legs.
(16) Republicans have been both obdurate and obtuse in Congress, where approval ratings have rarely scraped 20%.
(17) He is assertive (he insists on his photographer and dictates the terms of the interview), obdurate and, at times, wilfully contrary.
(18) We had an obdurate Labor party, a feckless Senate and a very difficult media culture,” Abbott said.
(19) In the years since those facts first became known, the story of the Holocaust has been told and retold, yet it still remains obdurately difficult to tell.
(20) Giles also remained obdurate and continued to refuse to resign even though he had only four supporters as against the conspirators’ nine.