What's the difference between induration and sclerosis?

Induration


Definition:

  • (n.) The act of hardening, or the process of growing hard.
  • (n.) State of being indurated, or of having become hard.
  • (n.) Hardness of character, manner, sensibility, etc.; obduracy; stiffness; want of pliancy or feeling.

Example Sentences:

  • (1) Phaso-contrast and interference microscopy investigations revealed in the damaged cells an induration of the sarcoplasmic matrix due to an increase in the dry matter concentration.
  • (2) The indurations from immediate and delayed hypersensitivity reactions were readily distinguishable, but the hyperthermic responses appeared to contain elements of both immediate and delayed hypersensitivity.
  • (3) This feature of ILC may also help explain why tumors may be palpable as areas of vague induration or thickening rather than as discrete masses.
  • (4) Since therapy performed by means of the moving head technique had beneficial effect on chronic prostatitis, plastic induration of the penis and the accompanying sexual potency disturbance, the method is recommended for use.
  • (5) Such a treatment augmented erythematous delayed reactions in animals immunized with BGG in CFA, but abolished induration at the reaction sites.
  • (6) While most of the clinical features--including diffuse mucosal inflammation, indurative edema, rash, and lymphadenopathy--are self-limiting, coronary artery aneurysms and the possibility of thrombotic occlusion occurs in up to 20% of children.
  • (7) We describe 2 patients who presented with chronic painful indurated swelling of one lower limb, thought at the time of referral to be due to chronic venous insufficiency.
  • (8) In the early postoperative period within an observation period from 3 to 19 months the characteristic and rather common complications in patients operated for hydrocele did not occur (hematocele, chylomas, which are mostly of ex vacuo type because of impaired blood supply and lymph system of the scrotum, abscesses, indurations of the scrotal and testicular tissues, relapses of the hydrocele, etc).
  • (9) Distal areas in systemic sclerosis (scleroderma), such as the dorsal skin of the hand are more frequently involved and more indurated than proximal areas.
  • (10) Clinical signs included lesions, indurations, and enlargement of lymph nodes.
  • (11) The precise basis of induration has not been established, although activation of the clotting system with consequent fibrin deposition has been clearly implicated.
  • (12) When IL-1 was injected intradermally into the backs of rabbits, the injection sites became indurated, erythematous, and warm to the touch after 4 hrs and annular lesions much like those of erythema chronicum migrans were seen in some animals after 24 hrs.
  • (13) In contrast to epicutaneous spongiotic contact dermatitis, HLA-DR was only seen on skin appendages and nearby basal keratinocytes in indurated tissue reactions with the exception of the reactions with focal basal cell layer disruption and an indurated patch test performed one week post angry back syndrome.
  • (14) A 52-year-old woman who had undergone an intrapleural sponge plombage operation because of tuberculosis, and had since shown an uneventful medical history for 35 years, was referred with a complaint of back skin induration over the previous surgical scar.
  • (15) The prevalence of tuberculous infection in a population is generally estimated from calculating the proportion of tested individuals who react with at least 10 mm of induration to 5 TU of PPD-S tuberculin.
  • (16) After 16 months, one of the two infected ewes suffered from indurative lymphocytic mastitis.
  • (17) In the guinea pigs an intradermal dose of PHA-P produced erythema and induration with a maximal response at 24 hours after the injection.
  • (18) Anergy, defined as no induration to any of four intradermal antigens, was present in 12%.
  • (19) Either the palpation method or the ball-point pen technique may be used to measure induration that results from TB skin testing.
  • (20) Similar, but less severe changes were seen at the site of skin tests on BCG-vaccinated subjects who were 'negative' by conventional criteria of measurement of dermal induration and they became greatly exaggerated after successful re-vaccination.

Sclerosis


Definition:

  • (n.) Induration; hardening; especially, that form of induration produced in an organ by increase of its interstitial connective tissue.
  • (n.) Hardening of the cell wall by lignification.

Example Sentences:

  • (1) Only group IV showed significant histological alterations such as glomerular sclerosis, interstitial damage, and increased glomerular area.
  • (2) We have therefore been unable to confirm that SV5 may be a major intrathecal immunogen in multiple sclerosis.
  • (3) Therapy was withheld after 19 months because of biliary sclerosis development.
  • (4) 18 patients with typical sporadic Amyotrophic Lateral Sclerosis (ALS) were investigated by the Motor Accuracy and Speed Test (MAST) and 18 healthy age- and-sex-matched volunteers, acted as controls.
  • (5) The thickness of the media in the groups behaves like the number of nuclei: in hypertension with the highest values, there is no significant decrease as far as the 8th cross-section, while in the coronary sclerosis and third decade groups the values come closer together after the 6th cross-section.
  • (6) In confirmation and extension of observations by Carp and his associates, brain tissue and sera from patients with multiple sclerosis (MS) were found to harbor an agent which induces a transitory depression in polymorphonuclear leukocytes (PMN) in mice as well as in rats, hamsters, and guinea pigs.
  • (7) Decreased maximal voluntary squeeze pressures were less severe in continent patients with multiple sclerosis than in incontinent patients with multiple sclerosis.
  • (8) This paper describes a family in which the first child, a girl born in 1988, has tuberous sclerosis (TS).
  • (9) Frozen brain specimens from patients with multiple sclerosis (MS) and other neurologic diseases were analyzed using immunocytochemical techniques for the presence of TNF.
  • (10) Copolymer 1 (Cop 1) is a synthetic basic random copolymer of amino acids that has been shown to be effective in suppression of experimental allergic encephalomyelitis and has been proposed as a candidate drug for multiple sclerosis.
  • (11) Comparing areas of sclerosis on x-ray with MRI changes, the real diameter of osteochondrosis dissecans can only be seen on MRI.
  • (12) A recent survey revealed 237 cases of multiple sclerosis in Wellington, New Zealand, giving an overall prevalence of 69 cases per 100,000.
  • (13) Herpes simplex virus type 1 was isolated from the cerebrospinal fluid of a patient during the first attack of multiple sclerosis.
  • (14) The lesion is most commonly located in the cortex of long bones where it is associated with dense, fusiform, reactive sclerosis.
  • (15) As experimental findings indicated inhibitory action of aromatic retinoid on microtubule polymerisation and collagen metabolism of mesenchymal cells, we decided to treat 5 patients suffering from progressive systemic sclerosis as well as 3 patients with Sharp's syndrome with aromatic retinoid (Tigason).
  • (16) Previous research has suggested that patients with amyotrophic lateral sclerosis (ALS) demonstrate similar psychological characteristics that distinguish them from the medically ill populations, and that these findings may bear etiologic and prognostic importance.
  • (17) A study of colour vision (CV) in 65 patients with multiple sclerosis (MS), (30 patients had had previous optic neuritis) and 51 controls was carried out with Ishihara's pseudoisochromatic plates (I-test), Farnsworth's panel D-15 test (F-test), and Lanthony's desaturated 15-hue test (L-test).
  • (18) Expression of proteins associated with immune function was investigated immunohistochemically in postmortem brain and spinal cord of patients with amyotrophic lateral sclerosis (ALS).
  • (19) ‘It’s hard to understand why we have all had to go through this’ – Angelene Wright, 66, from Lincolnshire I’m a carer for my 64-year-old husband who is in the final stages of multiple sclerosis.
  • (20) In the present study the lesions in MRI imaging were quantified and compared with the clinical and functional abnormalities in 56 patients (27 females and 29 males) with definite multiple sclerosis (MS).

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