(a.) Not effective; ineffectual; futile; inefficient; useless; as, an ineffective appeal.
Example Sentences:
(1) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(2) However, low dose heparin prophylasix is relatively ineffective in patients having hip surgery, and has not been evaluated in patients having other types of orthopaidic surgery.
(3) This mode of treatment remains appropriate for cases where antibiotics are ineffective and surgery impracticable.
(4) The excitatory effect of L-glutamate on PGCL sympathoexcitatory neurons was blocked by iontophoretic applications of kynurenic acid, whereas identical amounts of 8-OH kynurenic acid were ineffective.
(5) EGTA was ineffective in removing calmodulin from particulate preparations, but treatment with the tervalent metal ion La3+ resulted in a loss of up to 98% of calmodulin activity from these preparations.
(6) The use of UEBP-deficient female rat liver cytosol revealed that the afore-mentioned steroids are ineffective with respect to estrogen reception.
(7) Anti-histamine and anti-serotonin drugs, as well as substances capable of blocking synthesis of prostaglandins or activation of the kinin system, and also atropine, were ineffective in reducing the responses to TsTX or electrical stimuli.
(8) Treatment was ineffective and stopped in 12 cases (24.5%); the inefficacy was primary in 6 and tachyphylactic in the other 6.
(9) The delirium improved when the treatment was restored, whereas neuroleptics proved ineffective.
(10) The CI treatment induced almost full protection against these behavioral effects of saline stress but DS treatment was ineffective.
(11) In addition, it has excellent antibacterial activity against indole-positive Proteus strains against which conventional Cephalosporins are ineffective.
(12) Multimeric analysis of von Willebrand factor is necessary to diagnose von Willebrand's disease type II, in which DDAVP infusions should not be given since they are ineffective or may cause thrombocytopenia.
(13) It is concluded that under conditions in which other calcium release mechanisms operate well, InsP3 is relatively ineffective at releasing calcium from the SR in amounts sufficient to induce contraction.
(14) Hexa- and octasaccharides induced a slight increase in the number of acrosome reacted spermatozoa and disaccharides were ineffective.
(15) TE-031 was ineffective in 1 case of otitis media, but efficacious in 10 of 10 (100%) cases of upper respiratory infection, 15 of 18 (83.3%) cases of bronchitis and pneumonia, 5 of 6 (83.3%) cases of pertussis, 13 of 13 (100%) cases of mycoplasmal pneumonia, 4 of 4 (100%) cases of Chlamydia psittaci pneumonia, 16 of 16 (100%) cases of gastroenteritis (including 15 cases of Campylobacter gastroenteritis), and 1 (100%) case of impetigo.
(16) Preemployment screening methods have been ineffective in predicting those at risk, and in curbing the impact of back problems in industry.
(17) On siratro, CIAT899 induced nodules that were ineffective in acetylene reduction, whereas the EPS-deficient mutants induced effective nodules.
(18) Oligo- or polyribonucleotides are relatively ineffective initiators of polydeoxynucleotide polymerization.
(19) The H1-selective agonist, 2-(2-aminoethyl)thiazole was ineffective at doses 100 times greater than those of histamine.
(20) Anxiety disorders are no longer regarded as consequences of conflicts and ineffective defences or as concomitants of other psychiatric disorders but rather as disorders of their own.
Inefficacy
Definition:
(n.) Want of power to produce the desired or proper effect; inefficiency; ineffectualness; futility; uselessness; fruitlessness; as, the inefficacy of medicines or means.
Example Sentences:
(1) Treatment was ineffective and stopped in 12 cases (24.5%); the inefficacy was primary in 6 and tachyphylactic in the other 6.
(2) of these substances, or -- more accurately -- to a nitrogen inefficacy that they could provoke.
(3) Failure are due to overall inefficacy, dropouts from treatment and intolerance.
(4) Before 1966, they were mainly due to the choice of inefficacious operations.
(5) The case of a 55-year-old woman with a duodenal ulcer developing since 6 months is reported, in whom the surgical indication was early established on the basis of increasing of suffering and inefficacy of the medical treatment.
(6) The self-inefficacious stressed subjects were able to withstand increasing amounts of pain stimulation under saline conditions.
(7) Thirteen patients had to discontinue the treatment: 6 in the placebo group (inefficacy: 3 cases, anemia: 1 case, epigastric pain: 1 case, rash: 1 case) and 7 cases in the SI group (inefficacy: 2 cases, nauseous: 3 cases, abdominal pain: 1 case, moderate elevation of transaminases: 1 case).
(8) -in the second case, poor indications for selective intubation of the left main bronchus by left upper lobectomy initially foreseen, whereas pneumonectomy was necessary, hypoventilation, anoxia, cardiac inefficacy.
(9) Partial success with a good clinical result was obtained in 4 cases and there were 7 failures, 6 due to inefficacy of the drug, and 1 because of an extracardiac secondary effect.
(10) These results point to a basic inefficacy in the antiestrogen-receptor complex; although it is able to promote early tissue responses characteristic of an estrogen, these cannot be sufficiently maintained.
(11) We also have proved that dura mater tubes are inefficacious.
(12) The inefficacy of testosterone was attributed to the death of motoneurons before they could re-establish synaptic contact with targets, thereby rendering target-derived trophic substances stimulated by testosterone unable to rescue motoneurons in a timely manner.
(13) When hyponatremia develops, it worsens the already present secondary hyperaldosteronism and makes therapy with spironolactone inefficacious.
(14) Three out of the remaining nine patients stopped the therapy after 3 months because of inefficacy.
(15) During the study the drug had to be discontinued in 32 patients: because of inefficacy in 10, side effects in 11, both in nine, and in two because of unrelated events.
(16) There was inefficacy for left cardiac function of normal being.
(17) If the same tissues were infected via sensory nerves, following zosteriform spread of the virus the same treatments showed strongly decreased efficacy, or were inefficacious, when started before development of clinical signs in the infected tissues.
(18) It is suggested that determination of AI is used as a highly sensitive and operative test for routine monitoring of the patient's intraoperative condition and express diagnosis of inefficacy of anesthesia.
(19) Amiodarone may cause a broad variety of arrhythmias that are complicated by their extended duration and difficulty in distinguishing proarrhythmia from simple inefficacy.
(20) In patients who did not respond to DPA therapy, not only was the duration of the disease longer, but also previous therapy with other slow acting antirheumatic agents had been stopped because of inefficacy.