(a.) Not effective; ineffectual; futile; inefficient; useless; as, an ineffective appeal.
Example Sentences:
(1) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(2) However, low dose heparin prophylasix is relatively ineffective in patients having hip surgery, and has not been evaluated in patients having other types of orthopaidic surgery.
(3) This mode of treatment remains appropriate for cases where antibiotics are ineffective and surgery impracticable.
(4) The excitatory effect of L-glutamate on PGCL sympathoexcitatory neurons was blocked by iontophoretic applications of kynurenic acid, whereas identical amounts of 8-OH kynurenic acid were ineffective.
(5) EGTA was ineffective in removing calmodulin from particulate preparations, but treatment with the tervalent metal ion La3+ resulted in a loss of up to 98% of calmodulin activity from these preparations.
(6) The use of UEBP-deficient female rat liver cytosol revealed that the afore-mentioned steroids are ineffective with respect to estrogen reception.
(7) Anti-histamine and anti-serotonin drugs, as well as substances capable of blocking synthesis of prostaglandins or activation of the kinin system, and also atropine, were ineffective in reducing the responses to TsTX or electrical stimuli.
(8) Treatment was ineffective and stopped in 12 cases (24.5%); the inefficacy was primary in 6 and tachyphylactic in the other 6.
(9) The delirium improved when the treatment was restored, whereas neuroleptics proved ineffective.
(10) The CI treatment induced almost full protection against these behavioral effects of saline stress but DS treatment was ineffective.
(11) In addition, it has excellent antibacterial activity against indole-positive Proteus strains against which conventional Cephalosporins are ineffective.
(12) Multimeric analysis of von Willebrand factor is necessary to diagnose von Willebrand's disease type II, in which DDAVP infusions should not be given since they are ineffective or may cause thrombocytopenia.
(13) It is concluded that under conditions in which other calcium release mechanisms operate well, InsP3 is relatively ineffective at releasing calcium from the SR in amounts sufficient to induce contraction.
(14) Hexa- and octasaccharides induced a slight increase in the number of acrosome reacted spermatozoa and disaccharides were ineffective.
(15) TE-031 was ineffective in 1 case of otitis media, but efficacious in 10 of 10 (100%) cases of upper respiratory infection, 15 of 18 (83.3%) cases of bronchitis and pneumonia, 5 of 6 (83.3%) cases of pertussis, 13 of 13 (100%) cases of mycoplasmal pneumonia, 4 of 4 (100%) cases of Chlamydia psittaci pneumonia, 16 of 16 (100%) cases of gastroenteritis (including 15 cases of Campylobacter gastroenteritis), and 1 (100%) case of impetigo.
(16) Preemployment screening methods have been ineffective in predicting those at risk, and in curbing the impact of back problems in industry.
(17) On siratro, CIAT899 induced nodules that were ineffective in acetylene reduction, whereas the EPS-deficient mutants induced effective nodules.
(18) Oligo- or polyribonucleotides are relatively ineffective initiators of polydeoxynucleotide polymerization.
(19) The H1-selective agonist, 2-(2-aminoethyl)thiazole was ineffective at doses 100 times greater than those of histamine.
(20) Anxiety disorders are no longer regarded as consequences of conflicts and ineffective defences or as concomitants of other psychiatric disorders but rather as disorders of their own.
Vitiate
Definition:
(v. t.) To make vicious, faulty, or imperfect; to render defective; to injure the substance or qualities of; to impair; to contaminate; to spoil; as, exaggeration vitiates a style of writing; sewer gas vitiates the air.
(v. t.) To cause to fail of effect, either wholly or in part; to make void; to destroy, as the validity or binding force of an instrument or transaction; to annul; as, any undue influence exerted on a jury vitiates their verdict; fraud vitiates a contract.
Example Sentences:
(1) These conclusions vitiate previous explanations for gal3 associated long-term adaptation and noninducible phenotypes.
(2) Thus it is concluded that any solution or drug which needs to be injected should ideally be used at 37 degrees C, as temperature lower or higher than that may vitiate the results.
(3) Their review is marred by numerous errors which vitiate the potency estimates.
(4) Antibiotic therapy prior to hospitalization did not vitiate the validity of the test.
(5) The following is concluded: (1) diagnosis of folate and B12 deficiency based on SF, RCF and serum B12 is vitiated in HBT and needs a therapeutic trial; (2) iron overload of a magnitude indicated by TS greater than 50% can aggravate anemia in HBT.
(6) The technique is simple but the results may be vitiated by the minutae of preservation, of taking or of staining the cells which are described.
(7) Some of the previous results (Ascenzi et al., 1985) indicating a high hemoglobin titer were +vitiated because of an unexpected cross-reactivity of bone extracts with the hemoglobin-unreactive fraction of the antiserum.
(8) The authors have classified the various fractures of the pelvis in children by analysing the elements of functional prognosis of these lesions based on the types of fractures and on the particular factors of vitiation reported in the literature, consisting of series which are too short to be truly demonstrative.
(9) While the physiological role of these proteins remains to be determined, their presence in gonadal extracts or fluids vitiates assessment of FSH within the gonad by RIA using antiserum against hFSH.
(10) It was also found that the protective effect is vitiated by the concurrent administration of paraaminobenzoic acid.These studies indicate a need for further assessment of the antimalarial value of sulfones and sulfonamides, both alone and in combination with other drugs, for prevention and cure.
(11) In particular, the extent to which the generality of the model is vitiated by its ignoring the effect of mineralisation on strength was tested.
(12) These conclusions are not vitiated by differences in the number of nuclei within capillaries or in satellite cells, by differences in nuclear length or by variation in the degree to which fibres are contracted.
(13) Infection or ileal conduit urine vitiate the result as they produce high CEA levels in the urine in the absence of any neoplastic disease.
(14) It is argued that despite continued methodological improvements, subjects in the conditions of greater complexity may have found it sufficient to rotate only partial images, thereby vitiating the prediction.
(15) The failed bid by prime minister Antonis Samaras to throw off the yoke of international supervision by prematurely exiting the bailout programme has also vitiated his fragile government’s appeal.
(16) An investigation of the risky shift phenomenon revealed that an understanding of probability did not vitiate the shift toward greater risk.
(17) The several factors which do not depend directly on the orifice area or on the forward stroke volume vitiate the sole use of the orifice formula in the analysis of the dynamics of aortic stenosis.
(18) Mutations not detectable by analysis with the method of Southern with pDP1007, may occur in the testicular determinant factor gene vitiating testicular development.
(19) It is believed that a.m. are an important drawback contributing to vitiate any formula on the amount of muscle surgery to be performed in patients having no possibilities of restoring normal binocular vision.
(20) The stimulatory effect was vitiated by cycloheximide indicating the involvement of intermediate genes in the PLP gene activation.