(n.) Want of power to produce the desired or proper effect; inefficiency; ineffectualness; futility; uselessness; fruitlessness; as, the inefficacy of medicines or means.
Example Sentences:
(1) Treatment was ineffective and stopped in 12 cases (24.5%); the inefficacy was primary in 6 and tachyphylactic in the other 6.
(2) of these substances, or -- more accurately -- to a nitrogen inefficacy that they could provoke.
(3) Failure are due to overall inefficacy, dropouts from treatment and intolerance.
(4) Before 1966, they were mainly due to the choice of inefficacious operations.
(5) The case of a 55-year-old woman with a duodenal ulcer developing since 6 months is reported, in whom the surgical indication was early established on the basis of increasing of suffering and inefficacy of the medical treatment.
(6) The self-inefficacious stressed subjects were able to withstand increasing amounts of pain stimulation under saline conditions.
(7) Thirteen patients had to discontinue the treatment: 6 in the placebo group (inefficacy: 3 cases, anemia: 1 case, epigastric pain: 1 case, rash: 1 case) and 7 cases in the SI group (inefficacy: 2 cases, nauseous: 3 cases, abdominal pain: 1 case, moderate elevation of transaminases: 1 case).
(8) -in the second case, poor indications for selective intubation of the left main bronchus by left upper lobectomy initially foreseen, whereas pneumonectomy was necessary, hypoventilation, anoxia, cardiac inefficacy.
(9) Partial success with a good clinical result was obtained in 4 cases and there were 7 failures, 6 due to inefficacy of the drug, and 1 because of an extracardiac secondary effect.
(10) These results point to a basic inefficacy in the antiestrogen-receptor complex; although it is able to promote early tissue responses characteristic of an estrogen, these cannot be sufficiently maintained.
(11) We also have proved that dura mater tubes are inefficacious.
(12) The inefficacy of testosterone was attributed to the death of motoneurons before they could re-establish synaptic contact with targets, thereby rendering target-derived trophic substances stimulated by testosterone unable to rescue motoneurons in a timely manner.
(13) When hyponatremia develops, it worsens the already present secondary hyperaldosteronism and makes therapy with spironolactone inefficacious.
(14) Three out of the remaining nine patients stopped the therapy after 3 months because of inefficacy.
(15) During the study the drug had to be discontinued in 32 patients: because of inefficacy in 10, side effects in 11, both in nine, and in two because of unrelated events.
(16) There was inefficacy for left cardiac function of normal being.
(17) If the same tissues were infected via sensory nerves, following zosteriform spread of the virus the same treatments showed strongly decreased efficacy, or were inefficacious, when started before development of clinical signs in the infected tissues.
(18) It is suggested that determination of AI is used as a highly sensitive and operative test for routine monitoring of the patient's intraoperative condition and express diagnosis of inefficacy of anesthesia.
(19) Amiodarone may cause a broad variety of arrhythmias that are complicated by their extended duration and difficulty in distinguishing proarrhythmia from simple inefficacy.
(20) In patients who did not respond to DPA therapy, not only was the duration of the disease longer, but also previous therapy with other slow acting antirheumatic agents had been stopped because of inefficacy.
Inoperancy
Definition:
Example Sentences:
(1) Formerly, many patients in this category were considered either inoperable or candidates for total or partial nephrectomy.
(2) Almost all were inoperable by conventional techniques.
(3) When Hayley Cropper swallows poison on Coronation Street on Monday night, taking her own life to escape inoperable pancreatic cancer, with her beloved husband, Roy, in pieces at her bedside, it will be the end of a character who, thanks to Hesmondhalgh's performance, has captivated and challenged British TV viewers for 16 years.
(4) Survival in the inoperable group was short and showed no significant difference between treated and control patients.
(5) On 3 April he announced on his website that he had inoperable gall bladder cancer, giving him, at most, a year to live.
(6) The five-year survival rate for those patients with operable, resectable lesions was 33 percent, while for those with unilateral, inoperable, unresectable lesions, it was 10 percent.
(7) This choice was made on the basis of a clinical and angiographic estimate of the possible consequences of vessel occlusion, or dictated by sound inoperability of the patient.
(8) The condition of patients with transposition of the great arteries, intact ventricular septum and severe pulmonary vascular disease is inoperable with present techniques.
(9) The tumor was inoperable, and the patient was treated with chemotherapy.
(10) Seventy-three patients with regional, inoperable non-small-cell lung cancer received treatment with initial chemotherapy for two cycles (vinblastine-mitomycin followed in 3 weeks by vinblastine-cisplatin), with planned subsequent neutron irradiation to the primary site and concurrent, elective whole-brain irradiation using photons, followed by two more cycles of identical chemotherapy.
(11) The aim of the study was to assess vomit and pain control in terminal cancer patients with inoperable gastrointestinal obstruction, using a pharmacologic symptomatic treatment which prevents recourse to nasogastric tube placement and intravenous hydration, in hospital and home care settings.
(12) In a clinical randomized trial of 40 patients with inoperable lung carcinoma the success of radiotherapy alone (5000 rads) was compared with a combined modality with radiotherapy (5000 rads) and ICRF 159 (250 mg p.d.).
(13) Fifty-eight patients with inoperable adenocarcinoma of the pancreas were entered on the study, 47 were evaluable for response, and 57 were evaluable for toxicity.
(14) The second cyst was excised by cryoextraction 6 weeks after the initial surgery, but the eye developed an inoperable retinal detachment and phthisis bulbi.
(15) Survival and swallowing function were studied in a randomized trial of 97 patients with inoperable, localized esophageal carcinoma.
(16) An inoperable pituitary adenoma was a massive surrounding fibroblastic reaction was found at craniotomy.
(17) Endoscopic laser therapy is concluded to provide rapid, safe and excellent control of local symptoms in most patients with inoperable colorectal carcinoma, to be less useful when the tumour is large and circumferential and not effective in patients with incontinence.
(18) The third and fourth types characterized by intensive infrared radiation along all the anterior abdominal wall indicate mostly inoperable tumoral process.
(19) In some inoperable cases only biopsy of the lesion was possible.
(20) Chemotherapy with mitomycin C, ifosfamide and cisplatin (MIC) is reported to produce responses of 56% and 69% in inoperable non-small-cell lung cancer (NSCLC).