(n.) The act or process of infiltrating, as if water into a porous substance, or of a fluid into the cells of an organ or part of the body.
(n.) The substance which has entered the pores or cavities of a body.
Example Sentences:
(1) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
(2) In spite of dense lymphocytic infiltration only 3% of the tumor infiltrating lymphocytes exhibit the activation marker CD 25.
(3) The statistical T value calculated for the LP-TAE group showed that the administration of LP, the tumor size, intrahepatic metastasis, portal vein infiltration, and serum total bilirubin and alpha-fetoprotein levels significantly (P < 0.01) affected the patients' survival.
(4) Diseases of the gastric musculature, including the inflammatory and endocrine myopathies, muscular dystrophies, and infiltrative disorders, can result in significant gastroparesis.
(5) High mortality, severe destruction of pancreatic B-cells and presence of sporadic mononuclear infiltrations in islets and around excretory ducts were observed.
(6) We identified four distinct clinical patterns in the 244 patients with true positive MAI infections: (a) pulmonary nodules ("tuberculomas") indistinguishable from pulmonary neoplasms (78 patients); (b) chronic bronchitis or bronchiectasis with sputum repeatedly positive for MAI or granulomas on biopsy (58 patients, virtually all older white women); (c) cavitary lung disease and scattered pulmonary nodules mimicking M. tuberculosis infection (12 patients); (d) diffuse pulmonary infiltrations in immunocompromised hosts, primarily patients with AIDS (96 patients).
(7) The yeasts amounts used did not protect the test animals from the kidney infiltration with lipids and cholesterol; 12 g of yeasts per 100 g of the ration promoted elevation of sialic acid content in the blood plasma.
(8) Liver weight was increased by 49% due to infiltration of the liver with leukemic cells.
(9) In case of biliary and pancreatic duct obstruction with pure pancreatic reflux, both oedema and inflammatory infiltrations were evident, whereas, in the presence of biliary reflux too, more serious histological features were detected.
(10) The nature of these infiltrative foci remains uncertain; however, they are unlikely to have been of neoplastic origin and may be due to interleukin-2-induced lymphocytic infiltration.
(11) Light microscopy of both apneics and snorers revealed mucous gland hypertrophy with ductal dilation and focal squamous metaplasia, disruption of muscle bundles by infiltrating mucous glands, focal atrophy of muscle fibers, and extensive edema of the lamina propria with vascular dilation.
(12) A statistically significant association (P less than 0.01) was demonstrated between the degree of intratumoral lymphocytic infiltrate and the expression of HLA-DR and HLA-DQ antigens.
(13) In the univariate life-table analysis, recurrence-free survival was significantly related to age, pTNM category, tumour size, presence of certain growth patterns, tumour necrosis, tumour infiltration in surrounding thyroid tissue and thyroid gland capsule, lymph node metastases, presence of extra-nodal tumour growth and number of positive lymph nodes, whereas only tumour diameter, thyroid gland capsular infiltration and presence of extra-nodal tumour growth remained as significant prognostic factors in the multivariate analysis.
(14) Of the tumor-infiltrating lymphocytes, T-lymphocytes (mostly CD4+ cells) prevailed over B-lymphocytes.
(15) In the area of the porta hepatis, there were many epithelial luminal structures in fibrous tissue with inflammatory infiltrates.
(16) Staplers were used and therefore the choice between resection or amputation was determined by the degree of loco-regional infiltration of the neoplasm.
(17) Cyclosporine prevented lymphoid as well as macrophage infiltration of the transplant.
(18) The data indicate that activated helper T cells are required and sufficient to give rise to the inflammatory infiltrates that are characteristic of the inflammations and exacerbations in human rheumatoid arthritis.
(19) The expanded tumor-infiltrating cells were Leu-4+ T cells, and in five of six patients the majority were Leu-3+.
(20) Furthermore, non-coordinate expression of DR and DQW1 was present in 8 out of 40 carcinomas, with the proportion of DQW1 positive epithelium always being less than that of DR. Carcinomas exhibiting non-coordinate expression were never well differentiated; there was no relationship with the extent of the inflammatory infiltrate.
Percolation
Definition:
(n.) The act or process of percolating, or filtering; filtration; straining. Specifically (Pharm.), the process of exhausting the virtues of a powdered drug by letting a liquid filter slowly through it.
Example Sentences:
(1) As soon as the component with the lower mechanical stability is percolating the powder system, tablet hardness is controlled entirely by this component.
(2) This group consisted of 101 cases of whom 38 underwent semen treatment with Centrifugation on a Discontinuous Percoll Gradient (CDPG) and 63 with Pellet Swim-up (PS); the control group was made up of 31 normospermic patients where the semen was treated by PS.
(3) The attempt to fractionate the testicular cells by centrifugation in the continuous and discontinuous Percoll gradient was undertaken.
(4) The platelet subpopulations were separated with discontinuous gradients of Percoll.
(5) By using Percoll discontinuous density gradient centrifugation, peripheral blood nonphagocytic and nonadherent mononuclear cells were divided into the low and high density fractions for which natural killer (NK) cells and T cells were enriched, respectively.
(6) We conclude that both localized memory and percolation are possible in stimulatory idiotypic networks.
(7) The effect of activated PMN was tested on the motility of Percoll-washed spermatozoa in the presence and absence of reactive oxygen species scavengers or seminal plasma (whole or fractionated).
(8) To cope with this problem, in 27 IVF cycles, sperm selection was performed by centrifugation on discontinuous Percoll density gradient.
(9) Thirdly, the discontinuous percoll density gradient centrifugation was used to separate P. carinii cysts.
(10) Fractionation by Percoll density centrifugation of peripheral blood leucocyte cells, from atopic subjects with seasonal hay fever, unmasked IgE-B cell populations whose individual capacities to synthesize IgE in vitro were obscured in cultures of unfractionated B cells.
(11) Inspection of the cavity margins revealed absence of percolation at the dentin margins.
(12) In general, IEL of satisfactory yield and of good viability were obtained with EDTA treatment of the gut tissues, followed by rapid passages of the resultant cells through nylon-wool columns and centrifugation on two-step Percoll density gradients (45% and 80%).
(13) Basolateral membranes obtained by self-orienting Percoll-gradient centrifugation were treated with 5 mM CaCl2 to minimize the cross-contamination by brush border membranes.
(14) Percoll-purified high density small lymphocytes had little or no migratory capacity under these conditions, requiring a longer incubation time (4 hr) for consistent migration.
(15) Guinea pig marrow cell suspensions were first enriched for megakaryocytes by density equilibrium centrifugation in continuous Percoll density gradients.
(16) Using Percoll density gradient centrifugation, 1,25(OH)2D3 receptors could be localized in the basal cell fraction.
(17) After introduction of erythrocyte targets, there was a 20- to 30-min delay before initiation of phagocytosis that was not observed with monocytes prepared by the standard Percoll-gradient technique.
(18) To accomplish this, blood was obtained from patients with ragweed AR, granulocytes were isolated and fractionated by continuous density Percoll gradients, and the density distribution of these cells was determined after centrifugation.
(19) A cellular compartment from brown adipose tissue (BAT) of newborn rats was isolated by Percoll-density-gradient centrifugation and was shown to proliferate and to undergo adipose conversion in vitro in primary culture.
(20) Collagenase-dispersed cells from human chorion laeve were examined on Percoll gradients.