(v. t.) To check; to hold back; to restrain; to hinder.
(v. t.) To forbid; to prohibit; to interdict.
Example Sentences:
(1) Cellulase regulation appears to depend upon a complex relationship involving catabolite repression, inhibition, and induction.
(2) administration of the potent short-acting opioid, fentanyl, elicited inhibition of rhythmic spontaneous reflex increases in vesical pressure (VP) evoked by urinary bladder distension.
(3) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(4) The small units described here could be inhibitory interneurons which convert the excitatory response of large units into inhibition.
(5) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(6) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(7) This theory was confirmed by product analysis and by measuring the affinity of the substrate for the enzyme by its inhibition of p-nitrophenyl glucoside hydrolysis.
(8) The fate of the inhibited fungus is the subject of this report.
(9) The present study was therefore carried out to specify further which type of adrenoceptor is involved in lithium-induced hyperglycaemia and inhibition of insulin secretion.
(10) It is suggested that the normal cyclical release of LH is inhibited in PCO disease by a negative feedback by androgens to the hypothalamus or the pituitary, and that wedge resection should be reserved for patients in whom other forms of treatment have failed.
(11) For similar inotropic responses, normo- and hyperkalaemic dogs had similar levels of (Na+, K+)-ATPase inhibition and microsomal-bound digoxin.
(12) Dilutional studies comparing the mechanism of inhibition of monoamine oxidase produced by Gerovital H3 and by ipronizid demonstrated that Gerovital H3 was a reversible inhibitor of monoamine oxidase.
(13) Other research has indicated that placing gossypol in the vagina does inhibit the effect of herpes simplex virus type 2 infection, however.
(14) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(15) In Ca free-solution phenylephrine inhibited the response to CaCl2.
(16) MAF-G activity was inhibited by mitomycin C and colchicine, which inhibit DNA synthesis and mitosis, respectively, but not by 2-deoxy-D-glucose, an inhibitor of glucose metabolism.
(17) Based on these results, we concluded that the inhibition of putrefactive anaerobe 3679 by sorbate resulted from a stringent-type regulatory response induced by the protonophoric activity of sorbic acid.
(18) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(19) This mAb inhibited monocyte binding of both soluble FITC-labeled IgA and IgA-coated E, whereas it did not inhibit IgG binding.
(20) The inhibition was not seen in longitudinal muscle without myenteric plexus.
Shackle
Definition:
(n.) Stubble.
(n.) Something which confines the legs or arms so as to prevent their free motion; specifically, a ring or band inclosing the ankle or wrist, and fastened to a similar shackle on the other leg or arm, or to something else, by a chain or a strap; a gyve; a fetter.
(n.) Hence, that which checks or prevents free action.
(n.) A fetterlike band worn as an ornament.
(n.) A link or loop, as in a chain, fitted with a movable bolt, so that the parts can be separated, or the loop removed; a clevis.
(n.) A link for connecting railroad cars; -- called also drawlink, draglink, etc.
(n.) The hinged and curved bar of a padlock, by which it is hung to the staple.
(v. t.) To tie or confine the limbs of, so as to prevent free motion; to bind with shackles; to fetter; to chain.
(v. t.) Figuratively: To bind or confine so as to prevent or embarrass action; to impede; to cumber.
(v. t.) To join by a link or chain, as railroad cars.
Example Sentences:
(1) They will demand that the shackles be taken off local authorities so they can tackle a homelessness crisis.
(2) Shackles were found in the cellar, and yesterday police found a trap door.
(3) Shackling and ‘a full strip search’ On the morning of 21 October 2013, LaTonia Wilson was pulling out of her mechanic’s garage with her husband, Atheris Mann; her eldest son, Jessie Patrick; and their two-year-old son Marquise.
(4) How Chicago police used pot to disappear young people at Homan Square Read more Davis, a Democrat who represents the neighborhood that includes the Homan Square site, had until Wednesday only said publicly that he would “strongly support” a federal inquiry into what 11 detainees – in strikingly similar detailed accounts provided to the Guardian – have described as extended interrogation without access to legal counsel or their families, often while shackled.
(5) On this evidence, the shackles, in place ever since that World Cup in France, finally appear to be off.
(6) It is modern slavery enforced not through shackles and whips, but by fiddled contracts, missing permits and paperwork and the Guardian has found it happening just down the road from the desert palace of Qatar’s emir, Sheikh Tamim bin Khalifa al-Thani.
(7) Mané, in particular, has become erratic, while Tadic has suffered from the fact that opponents have studied him after his sparkling start to the campaign and increased their efforts to shackle him, partially by curtailing the ability of Southampton’s flying full-backs to support him down the flanks.
(8) Military policy Victory on Sunday will boost attempts by Abe and his fellow conservatives to further loosen the political shackles on Japan’s self-defence forces – actually a highly trained, well-equipped army, navy and air force.
(9) The NHS has experienced numerous attempts to free staff from the shackles of unnecessary paperwork to allow more time for patient care.
(10) The blindfold, shackles, threats and beatings were just the white noise of his ordeal, he says.
(11) Second, its shackled to historicism, constantly looking to the past.
(12) We face the prospect of a week of party manifestos full of reckless promises unbelieved by electors yet shackling future chancellors.
(13) It is so nice that the shackles have been taken off me and I can now fight for America the way I want to,” he tweeted .
(14) I would love to see the selection criteria for that job.’” Facebook Twitter Pinterest From a blindfolded boat ride to threats against his family members and hours shackled to Gitmo floors, Zuley’s interrogation of Mohamedou Ould Slahi shocked investigators.
(15) "He was not only able to break the shackles of bigotry and bias and hate, but he did it without internalising the battles he was fighting."
(16) In March, Gambian president Yahya Jammeh announced plans to throw off the shackles of the colonial past by discontinuing the use of English as an official language .
(17) Sir Edward Leigh, a former minister, said breaking up the coalition would be one way of showing fed-up Conservative voters that Cameron was serious about addressing their concerns, instead of being shackled to the Liberal Democrats .
(18) But even allowing for that fact, and the long-known departure of Lampard, this will undoubtedly be a summer of upheaval for last season’s champions, not least with Uefa looking increasingly likely to loosen the shackles of financial fair play.
(19) Not only are their pay and rations fixed centrally but their revenue is shackled.
(20) When she fled the violence of Honduras and settled with relatives in Atlanta, Gutiérrez, 31, met regularly with immigration officials and wore an electronic ankle shackle, so they could track her.