What's the difference between initial and leading?

Initial


Definition:

  • (a.) Of or pertaining to the beginning; marking the commencement; incipient; commencing; as, the initial symptoms of a disease.
  • (a.) Placed at the beginning; standing at the head, as of a list or series; as, the initial letters of a name.
  • (n.) The first letter of a word or a name.
  • (v. t.) To put an initial to; to mark with an initial of initials.

Example Sentences:

  • (1) He added: "There is a rigorous review process of applications submitted by the executive branch, spearheaded initially by five judicial branch lawyers who are national security experts and then by the judges, to ensure that the court's authorizations comport with what the applicable statutes authorize."
  • (2) In January 2011, the Nobel peace prize laureate was admitted to a Johannesburg hospital for what officials initially described as tests but what turned out to be an acute respiratory infection .
  • (3) Apparently, the irradiation with visible light of a low intensity creates an additional proton gradient and thus stimulates a new replication and division cycle in the population of cells whose membranes do not have delta pH necessary for the initiation of these processes.
  • (4) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
  • (5) Needle acupuncture did, however, increase the pain threshold compared with the initial value (alpha = 0.1%).
  • (6) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
  • (7) Other haematological parameters remained normal, with the exception of the absolute number of lymphocytes, which initially fell sharply but soon returned to, and even exceeded, control levels.
  • (8) Errors in the initial direction of response were fewer in binocular viewing in comparison with monocular viewing.
  • (9) The results also indicate that small lesions initially noted only on CT scans of the chest in children with Wilms' tumor frequently represent metastatic tumor.
  • (10) An initial complex-soma inflection was observed on the rising phase of the action potential of some cells.
  • (11) In the past 6 years 26 patients underwent operation for recurrent duodenal ulcer after what was considered to be an "adequate" initial operation.
  • (12) Plain radiographs should be the initial screening modality for a suspected foreign body.
  • (13) In the 153 women to whom iron supplements were given during pregnancy, the initial fall in haemoglobin concentration was less, was arrested by 28 weeks gestation and then rose to a level equivalent to the booking level.
  • (14) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
  • (15) At low concentrations of TFIC there is a more or less direct relationship between the amount of the factor and the number of initiated complexes formed.
  • (16) During the 1st h after induction of the sporulation process, the rate of protein synthesis increased to two times the initial value.
  • (17) Benefits increase with an individual's initial cholesterol level and decrease with the age at which an intervention is initiated.
  • (18) Charge data from the target hospital showed a statistically significant reduction in laboratory charges per patient in the quarter following program initiation (P = 0.02) and no evidence for change in a group of five comparison hospitals.
  • (19) The most pronounced changes occurred during the initial hours of nutrient and energy deprivation.
  • (20) Damage to this innervation is often initiated by childbirth, but appears to progress during a period of many years so that the functional disorder usually presents in middle life.

Leading


Definition:

  • (p. pr. & vb. n.) of Lead
  • (p. pr. & vb. n.) of Lead
  • (a.) Guiding; directing; controlling; foremost; as, a leading motive; a leading man; a leading example.
  • (n.) The act of guiding, directing, governing, or enticing; guidance.
  • (n.) Suggestion; hint; example.

Example Sentences:

  • (1) Thirty-two patients (10 male, 22 female; age 37-82 years) undergoing maintenance haemodialysis or haemofiltration were studied by means of Holter device capable of simultaneously analysing rhythm and ST-changes in three leads.
  • (2) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
  • (3) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
  • (4) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
  • (5) These are typically runaway processes in which global temperature rises lead to further releases of CO², which in turn brings about more global warming.
  • (6) Results indicated a .85 probability that Directive Guidance would be followed by Cooperation; a .67 probability that Permissiveness would lead to Noncooperation; and a .97 likelihood that Coerciveness would lead to either Noncooperation or Resistance.
  • (7) It would be fascinating to see if greater local government involvement in running the NHS in places such as Manchester leads over the longer term to a noticeable difference in the financial outlook.
  • (8) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
  • (9) Our results indicate that increasing the delay for more than 8 days following irradiation and TCD syngeneic BMT leads to a rapid loss of the ability to achieve alloengraftment by non-TCD allogeneic bone marrow.
  • (10) report the complications registered, in particular: lead's displacing 6.2%, run away 0.7%, marked hyperthermya 0.0%, haemorrage 0.4%, wound dehiscence 0.3%, asectic necrosis by decubitus 5%, septic necrosis 0.3%, perforation of the heart 0.2%, pulmonary embolism 0.1%.
  • (11) The availability and success of changes in reproductive technology should lead to a reappraisal of the indications for hysterectomy, especially in young women.
  • (12) Photoirradiation of F1 in the presence of the analog leads to inactivation depending linearly on the incorporation of label.
  • (13) In patients with coronary artery disease, electrocardiographic signs of left atrial enlargement (LAE-negative P wave deflection greater than or equal to 1 mm2 in lead V1) are associated with increased left ventricular end diastolic pressure (LVEDP).
  • (14) The new Somali government has enthusiastically embraced the new deal and created a taskforce, bringing together the government, lead donors (the US, UK, EU, Norway and Denmark), the World Bank and civil society.
  • (15) Suggested is a carefully prepared system of cycling videocassettes, to effect the dissemination of current medical information from leading medical centers to medical and paramedical people in the "bush".
  • (16) Mitonafide is the lead compound of a new series of antitumor drugs, the 3-Nitronaphthalimides, which have shown antineoplastic activity in vitro as well as in vivo.
  • (17) The presently available data allow us to draw the following conclusions: 1) G proteins play a mediatory role in the transmission of the signal(s) generated upon receptor occupancy that leads to the observed cytoskeletal changes.
  • (18) In the case presented, overdistension of a jejunostomy catheter balloon led to intestinal obstruction and pressure necrosis (of the small bowel), with subsequent abscess formation leading to death from septicemia.
  • (19) This is rapidly followed by a gamut of changes leading to demyelination.
  • (20) In crosses between inverted repeats, a single intrachromatid reciprocal exchange leads to inversion of the sequence between the crossover sites and recovery of both genes involved in the event.