(1) Permeabilized rat hepatocytes were used to study the effects of inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and GTP on Ca2+ uptake and release by ATP-dependent intracellular Ca2+ storage pools.
(2) In this review, we discuss the ligand recognition characteristics of Ins(1,4,5)P3 receptors, and their functional properties in their native environment and after purification, and we relate these properties to what is known of the structure of the receptor.
(3) The growth factor produces an initial, rapid increase in the level of inositol 1,4,5-trisphosphate (Ins-1,4,5-P3) due to hydrolysis of phosphatidyl-inositol-4,5-bisphosphate (Wahl, M., Sweatt, J. D., and Carpenter, G. (1987) Biochem.
(4) Yesterday student occupations were continuing in at least nine universities – including sit-ins in Leeds, Cambridge, Manchester, Edinburgh, University College London, Brighton, Newcastle and the School of African and Oriental Studies in London.
(5) Of the many inositol phosphates recently identified in angiotensin-II-stimulated adrenal glomerulosa and other cells, Ins(1,3,4,5)P4 has been implicated as an additional second messenger that may act in conjunction with Ins(1,4,5)P3 to elicit Ca2+ mobilization.
(6) Among the genes located in 11p15, c-Ha-ras 1 (HRAS1), insulin (INS), and insulin-like growth factor II (IGF2) may account for the clinical features and the increased risk for malignancy.
(7) Cerebellar and adrenal microsomes were used in a ligand-displacement mass assay (conducted under near-physiological conditions, at pH 7.0) on extracts of cerebral-cortex slices stimulated with agonists, and both preparations faithfully detected the increases in Ins(1,3,4,5)P4 that occurred, implying that Ins(1,3,4,5)P4 is the principal ligand on these binding sites in intact cells.
(8) Hence this response differs from the well-characterized Ins(1,4,5)P3 responses of many other systems.
(9) SJ Burnley Ins Michael Keane (Man Utd, £2m) Outs None Sean Dyche’s aim was to retain Danny Ings at all costs and secure more Premier League experience.
(10) I’ve had run-ins with Virgin train lavatories too.
(11) But the outspoken journalist and human rights activist has long been a thorn in Ali Abdullah Saleh's side, agitating for press freedoms and staging weekly sit-ins to demand the release of political prisoners from jail – a place she has been several times herself.
(12) Daily drop-ins and monthly class passes are available.
(13) A subclone containing this inserted DNA (ins 3) hybridizes primarily to rDNA-containing sequences in in situ and genomic blot hybridization experiments.
(14) In blacks, homozygotes for the ins allele had the least involvement of the thoracic and the abdominal aorta with lesions, homozygotes for the del allele had the greatest involvement, and heterozygotes had intermediate involvement (p = 0.0328 for thoracic aorta, p = 0.0104 for abdominal aorta), but no differences were found in whites.
(15) The Ins(1,2,6)P3-K system was ascertained using Sammartano's method which additionally enabled the influence of various K+ concentrations on the protonations constants to be considered.
(16) The same accumulation of Ins(1,3,4,5,6)P5 occurred during neutrophil differentiation, whether it was induced by dimethylsulphoxide or by a combination of retinoic acid and a T-lymphocyte cell line-derived differentiation factor.
(17) This contrasts with the expectation, based on results with cell-free systems, that Ins(1,3,4,6)P4 is synthesized by the direct phosphorylation of Ins(1,3,4)P3.
(18) IgA specific for 7 food and 6 airborne antigens were sought in the serum of 30 adult patients with IgA mesangial nephropathy (IgA GN), 23 with membranous nephropathy (MGN), 20 with idiopathic nephrotic syndrome (INS), 11 with membranoproliferative GN (MPGN) and 22 healthy controls by means of an enzyme-linked immunoassay.
(19) When adipose tissue is incubated first with INS followed by EPI, PDE is activated.
(20) Simultaneously, cellular Ins(1,4,5)P3 contents became markedly elevated, suggesting an AlF4- activation of a phospholipase C-specific G-protein.
Interior
Definition:
(a.) Being within any limits, inclosure, or substance; inside; internal; inner; -- opposed to exterior, or superficial; as, the interior apartments of a house; the interior surface of a hollow ball.
(a.) Remote from the limits, frontier, or shore; inland; as, the interior parts of a region or country.
(n.) That which is within; the internal or inner part of a thing; the inside.
(n.) The inland part of a country, state, or kingdom.
Example Sentences:
(1) Pint from £2.90 The Duke Of York With its smart greige interior, flagstone floor and extensive food menu (not tried), this newcomer feels like a gastropub.
(2) Mike Enzi of Wyoming A senior senator from Wyoming, Enzi worked for the Department of Interior and the private Black Hills Corporation before being elected to Congress.
(3) As for Scotland Soccer Club, Altidore's deputy at franchise level, Steven Fletcher, is gonna be the guy that the hosts will look to kick the soccer ball in to the soccer goal interior.
(4) The adsorption of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) as well as of other dipolar molecules to the interface of artificial lipid membranes gives rise to a change of the dipole potential between the membrane interior and water.
(5) The interior minister, Miguel Ángel Osorio Chong, left a gathering of the Mexican diplomatic corps to take a call from President Enrique Peña Nieto.
(6) While X-ray crystallographic data on cytochrome c show the reduced and oxidized forms to have very similar structures, there is a considerable body of data, mostly from solution studies, that indicates the reduced form is more stable and that the interior of the protein is less accessible to solvent in this state.
(7) By whatever mechanism cholesterol is forced to be translocated from the plasma membranes subsequent to the degradation of sphingomyelin, it appears that the sterol flow is specifically directed towards the interior of the cells.
(8) Ukraine map An aide to Ukraine's interior minister posted on Facebook that rebels had begun surrendering in some areas of Kiev's "anti-terrorist operation", and the newspaper Ukrainskaya Pravda reported that some rebels were asking for a corridor to put down their arms and leave areas surrounded by government forces.
(9) The EU interior ministers issued a joint statement in which they agreed to renew pressure on the major internet companies to step up their efforts to swiftly report and remove material that aims to incite hatred and terror.
(10) Merkel’s interior and finance ministers, both in the same party, regularly contradict her.
(11) The caption blamed "the dogs of the Interior [ministry]", and claimed that incendiary bombs had been fired at the building by police, "causing a very big fire" that "burned everything to ashes".
(12) The interior ministry official Konrad Kogler denied that the clampdown, which includes increased checks on the eastern borders, violated the Schengen accord on free movement.
(13) On Monday, the interior minister, Miguel Ángel Osorio Chong, said the alarm had been raised immediately, but local media have cited prison sources saying it took half an hour for police to begin the search for Guzmán.
(14) Others wrecked the villa interior, poured fuel on the floor and set it alight.
(15) Liberated from the life of middle- and upper-class interiors, with all its codes of conduct and formalities, they gave new names to each other, and pushed the limits of the dominant morality.
(16) Under appropriate conditions, high absolute interior concentrations of the drug can be achieved (approximately 120 mM) in combination with high trapping efficiencies (in excess of 90%).
(17) In this more nearly globular shape, CAM reveals to the environment two interior pockets that contain a number of hydrophobic residues, in agreement with NMR data suggesting involvement of such residues in the binding of inhibitors and proteins to CAM.
(18) A series of cytochalasin-sensitive morphologic changes that are undergone by the parasite and the host cell lead to the interiorization of the parasite.
(19) Membrane-bound receptor or enzyme distribution between cell surface and cell interior can be determined using the non-ionic detergent digitonin.
(20) Concentrate on the way he constructs the space of an interior or orchestrates a sensual camera movement that he invented himself - the camera gliding on unseen tracks in one direction while uncannily panning in another direction - and you perceive how each Dreyer film almost brutally reconstructs the universe rather than accepting it as a familiar given.