(1) Permeabilized rat hepatocytes were used to study the effects of inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and GTP on Ca2+ uptake and release by ATP-dependent intracellular Ca2+ storage pools.
(2) In this review, we discuss the ligand recognition characteristics of Ins(1,4,5)P3 receptors, and their functional properties in their native environment and after purification, and we relate these properties to what is known of the structure of the receptor.
(3) The growth factor produces an initial, rapid increase in the level of inositol 1,4,5-trisphosphate (Ins-1,4,5-P3) due to hydrolysis of phosphatidyl-inositol-4,5-bisphosphate (Wahl, M., Sweatt, J. D., and Carpenter, G. (1987) Biochem.
(4) Yesterday student occupations were continuing in at least nine universities – including sit-ins in Leeds, Cambridge, Manchester, Edinburgh, University College London, Brighton, Newcastle and the School of African and Oriental Studies in London.
(5) Of the many inositol phosphates recently identified in angiotensin-II-stimulated adrenal glomerulosa and other cells, Ins(1,3,4,5)P4 has been implicated as an additional second messenger that may act in conjunction with Ins(1,4,5)P3 to elicit Ca2+ mobilization.
(6) Among the genes located in 11p15, c-Ha-ras 1 (HRAS1), insulin (INS), and insulin-like growth factor II (IGF2) may account for the clinical features and the increased risk for malignancy.
(7) Cerebellar and adrenal microsomes were used in a ligand-displacement mass assay (conducted under near-physiological conditions, at pH 7.0) on extracts of cerebral-cortex slices stimulated with agonists, and both preparations faithfully detected the increases in Ins(1,3,4,5)P4 that occurred, implying that Ins(1,3,4,5)P4 is the principal ligand on these binding sites in intact cells.
(8) Hence this response differs from the well-characterized Ins(1,4,5)P3 responses of many other systems.
(9) SJ Burnley Ins Michael Keane (Man Utd, £2m) Outs None Sean Dyche’s aim was to retain Danny Ings at all costs and secure more Premier League experience.
(10) I’ve had run-ins with Virgin train lavatories too.
(11) But the outspoken journalist and human rights activist has long been a thorn in Ali Abdullah Saleh's side, agitating for press freedoms and staging weekly sit-ins to demand the release of political prisoners from jail – a place she has been several times herself.
(12) Daily drop-ins and monthly class passes are available.
(13) A subclone containing this inserted DNA (ins 3) hybridizes primarily to rDNA-containing sequences in in situ and genomic blot hybridization experiments.
(14) In blacks, homozygotes for the ins allele had the least involvement of the thoracic and the abdominal aorta with lesions, homozygotes for the del allele had the greatest involvement, and heterozygotes had intermediate involvement (p = 0.0328 for thoracic aorta, p = 0.0104 for abdominal aorta), but no differences were found in whites.
(15) The Ins(1,2,6)P3-K system was ascertained using Sammartano's method which additionally enabled the influence of various K+ concentrations on the protonations constants to be considered.
(16) The same accumulation of Ins(1,3,4,5,6)P5 occurred during neutrophil differentiation, whether it was induced by dimethylsulphoxide or by a combination of retinoic acid and a T-lymphocyte cell line-derived differentiation factor.
(17) This contrasts with the expectation, based on results with cell-free systems, that Ins(1,3,4,6)P4 is synthesized by the direct phosphorylation of Ins(1,3,4)P3.
(18) IgA specific for 7 food and 6 airborne antigens were sought in the serum of 30 adult patients with IgA mesangial nephropathy (IgA GN), 23 with membranous nephropathy (MGN), 20 with idiopathic nephrotic syndrome (INS), 11 with membranoproliferative GN (MPGN) and 22 healthy controls by means of an enzyme-linked immunoassay.
(19) When adipose tissue is incubated first with INS followed by EPI, PDE is activated.
(20) Simultaneously, cellular Ins(1,4,5)P3 contents became markedly elevated, suggesting an AlF4- activation of a phospholipase C-specific G-protein.
Internal
Definition:
(a.) Inward; interior; being within any limit or surface; inclosed; -- opposed to external; as, the internal parts of a body, or of the earth.
(a.) Derived from, or dependent on, the thing itself; inherent; as, the internal evidence of the divine origin of the Scriptures.
(a.) Pertaining to its own affairs or interests; especially, (said of a country) domestic, as opposed to foreign; as, internal trade; internal troubles or war.
(a.) Pertaining to the inner being or the heart; spiritual.
(a.) Intrinsic; inherent; real.
(a.) Lying toward the mesial plane; mesial.
Example Sentences:
(1) The Wales international and Port Vale defender Clayton McDonald both admitted having sex with the victim, – McDonald was found not guilty of the same charge.
(2) City badly missed Yaya Touré, on international duty at the Africa Cup of Nations, and have not won a league match since last April when he has been missing.
(3) Experience of pain is modified by intern and extern influences, and it can appear very multiformly in the chronicity.
(4) Only 81 cases are reported in the international literature.
(5) After 3 and 6 months, blood collected by cardiocentesis using ether anesthesia and then sacrificed to remove CNS and internal organs.
(6) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(7) A total of 104 evaluable patients 20-90 years old treated by direct vision internal urethrotomy a.m. Sachse for urethral strictures reported retrospectively via a questionnaire their sexual potency before and after internal urethrotomy.
(8) But earlier this year the Unesco world heritage committee called for the cancellation of all such Virunga oil permits and appealed to two concession holders, Total and Soco International, not to undertake exploration in world heritage sites.
(9) Patrice Evra Evra Handed a five-match international ban for his part in the France squad’s mutiny against Raymond Domenech at the 2010 World Cup, it took Evra almost a year to force his way back in.
(10) The International Monetary Fund, which has long urged Nigeria to remove the subsidy, supports the move.
(11) The article describes an unusual case with development of a right anterior mediastinal mass after bypass surgery with internal mammary artery grafts.
(12) Some international coverage of the outbreak was accused of misinforming western readers.
(13) Evaluation revealed tricuspid insufficiency, a massively dilated right internal jugular vein, and obstruction of the left internal jugular vein.
(14) He voiced support for refugees, trade unions, council housing, peace, international law and human rights.
(15) UN internal investigators delivered a report to the then secretary general, Kofi Annan, but it was not published.
(16) The very young history of clinical Psychology is demonstrating the value of clinical Psychologist in the socialistic healthy work and the international important positions of special education to psychological specialist of medicine.
(17) Writing in the Observer , Schmidt said his company's accounts were complicated but complied with international taxation treaties that allowed it to pay most of its tax in the United States.
(18) Macrophages internalize aggregated low density lipoprotein (LDL) by LDL receptor-dependent phagocytosis.
(19) This observation, reinforced by simultaneous determinations of cortisol levels in the internal spermatic and antecubital veins, practically excluded the validity of the theory of adrenal hormonal suppression of testicular tissues.
(20) However, he has also insisted that North Korea live up to its own commitments, adhere to its international obligations and deal peacefully with its neighbours.