(1) Permeabilized rat hepatocytes were used to study the effects of inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and GTP on Ca2+ uptake and release by ATP-dependent intracellular Ca2+ storage pools.
(2) In this review, we discuss the ligand recognition characteristics of Ins(1,4,5)P3 receptors, and their functional properties in their native environment and after purification, and we relate these properties to what is known of the structure of the receptor.
(3) The growth factor produces an initial, rapid increase in the level of inositol 1,4,5-trisphosphate (Ins-1,4,5-P3) due to hydrolysis of phosphatidyl-inositol-4,5-bisphosphate (Wahl, M., Sweatt, J. D., and Carpenter, G. (1987) Biochem.
(4) Yesterday student occupations were continuing in at least nine universities – including sit-ins in Leeds, Cambridge, Manchester, Edinburgh, University College London, Brighton, Newcastle and the School of African and Oriental Studies in London.
(5) Of the many inositol phosphates recently identified in angiotensin-II-stimulated adrenal glomerulosa and other cells, Ins(1,3,4,5)P4 has been implicated as an additional second messenger that may act in conjunction with Ins(1,4,5)P3 to elicit Ca2+ mobilization.
(6) Among the genes located in 11p15, c-Ha-ras 1 (HRAS1), insulin (INS), and insulin-like growth factor II (IGF2) may account for the clinical features and the increased risk for malignancy.
(7) Cerebellar and adrenal microsomes were used in a ligand-displacement mass assay (conducted under near-physiological conditions, at pH 7.0) on extracts of cerebral-cortex slices stimulated with agonists, and both preparations faithfully detected the increases in Ins(1,3,4,5)P4 that occurred, implying that Ins(1,3,4,5)P4 is the principal ligand on these binding sites in intact cells.
(8) Hence this response differs from the well-characterized Ins(1,4,5)P3 responses of many other systems.
(9) SJ Burnley Ins Michael Keane (Man Utd, £2m) Outs None Sean Dyche’s aim was to retain Danny Ings at all costs and secure more Premier League experience.
(10) I’ve had run-ins with Virgin train lavatories too.
(11) But the outspoken journalist and human rights activist has long been a thorn in Ali Abdullah Saleh's side, agitating for press freedoms and staging weekly sit-ins to demand the release of political prisoners from jail – a place she has been several times herself.
(12) Daily drop-ins and monthly class passes are available.
(13) A subclone containing this inserted DNA (ins 3) hybridizes primarily to rDNA-containing sequences in in situ and genomic blot hybridization experiments.
(14) In blacks, homozygotes for the ins allele had the least involvement of the thoracic and the abdominal aorta with lesions, homozygotes for the del allele had the greatest involvement, and heterozygotes had intermediate involvement (p = 0.0328 for thoracic aorta, p = 0.0104 for abdominal aorta), but no differences were found in whites.
(15) The Ins(1,2,6)P3-K system was ascertained using Sammartano's method which additionally enabled the influence of various K+ concentrations on the protonations constants to be considered.
(16) The same accumulation of Ins(1,3,4,5,6)P5 occurred during neutrophil differentiation, whether it was induced by dimethylsulphoxide or by a combination of retinoic acid and a T-lymphocyte cell line-derived differentiation factor.
(17) This contrasts with the expectation, based on results with cell-free systems, that Ins(1,3,4,6)P4 is synthesized by the direct phosphorylation of Ins(1,3,4)P3.
(18) IgA specific for 7 food and 6 airborne antigens were sought in the serum of 30 adult patients with IgA mesangial nephropathy (IgA GN), 23 with membranous nephropathy (MGN), 20 with idiopathic nephrotic syndrome (INS), 11 with membranoproliferative GN (MPGN) and 22 healthy controls by means of an enzyme-linked immunoassay.
(19) When adipose tissue is incubated first with INS followed by EPI, PDE is activated.
(20) Simultaneously, cellular Ins(1,4,5)P3 contents became markedly elevated, suggesting an AlF4- activation of a phospholipase C-specific G-protein.
Just
Definition:
(a.) Conforming or conformable to rectitude or justice; not doing wrong to any; violating no right or obligation; upright; righteous; honest; true; -- said both of persons and things.
(a.) Not transgressing the requirement of truth and propriety; conformed to the truth of things, to reason, or to a proper standard; exact; normal; reasonable; regular; due; as, a just statement; a just inference.
(a.) Rendering or disposed to render to each one his due; equitable; fair; impartial; as, just judge.
(adv.) Precisely; exactly; -- in place, time, or degree; neither more nor less than is stated.
(adv.) Closely; nearly; almost.
(adv.) Barely; merely; scarcely; only; by a very small space or time; as, he just missed the train; just too late.