(v. t.) Fig.: To introduce into the mind; -- used especially of harmful ideas or principles; to imbue; as, to inoculate one with treason or infidelity.
(v. t.) To bud; to insert, or graft, as the bud of a tree or plant in another tree or plant.
(v. t.) To insert a foreign bud into; as, to inoculate a tree.
(v. t.) To communicate a disease to ( a person ) by inserting infectious matter in the skin or flesh; as, to inoculate a person with the virus of smallpox,rabies, etc. See Vaccinate.
(v. i.) To graft by inserting buds.
(v. i.) To communicate disease by inoculation.
Example Sentences:
(1) Whereas strain Ga-1 was practically avirulent for mice, strain KL-1 produced death by 21 days in 50% of the mice inoculated.
(2) Charcoal particles coated with the lipid extract were prepared and the suspension inoculated intravenously into mice.
(3) The treatment was started either immediately or delayed for 48 h after peritoneal inoculation.
(4) Plaque size, appearance, and number were influenced by diluent, incubation temperature after nutrient overlay, centrifugation of inoculated tissue cultures, and number of host cells planted initially in each flask.
(5) This suggested that some of the cell population became metabolically inactive at a very early stage, possibly owing to suboptimal conditions of growth.Glycine, lysozyme and lithium chloride initiated lysis of BCG growth in the aforementioned media 24-48 hours after inoculation.
(6) A total of 28 cell lines were selected for Geneticin - resistance and inoculated into the footpads of syngeneic animals following co-transfection with pSV2neo and genomic DNA, or transfection with plasmid constructs containing neo and the activated Ha-ras oncogene.
(7) None of the animals injected with either CD4+ or CD8+ T cells became overtly diabetic during the 30 days of observation whereas 8 of 23 mice inoculated with a mixture of the two subsets developed glycosuria and hyperglycemia.
(8) The hypothesis that experimentally determined survival times of Treponema pallidum in stored donor blood could be related to the number of treponemes initially present in the treponeme-blood mixtures was investigated by inoculating rabbits with three graded doses of treponemes suspended in donor blood and stored at 4 degrees C for various periods of time.
(9) Microfilariae were detected fro 2-136 days after inoculation.
(10) In contrast, albino rats and rabbits failed to succumb to overt disease by subcutaneous and intraperitoneal routes of inoculation.
(11) A large number of recently isolated bacterial pathogens were tested for susceptibility to cephalexin and cephaloglycin by the replica inoculating method.
(12) Five control rabbits developed severe diarrhea within 72 h after inoculation with enterotoxigenic E. coli B16-4.
(13) Specific antisera prepared in rabbits or in foot-pad-inoculated chickens were adequate for culture typing.
(14) It also showed weak inhibition of the solid type of Ehrlich carcinoma and prolonged the survival period of mice inoculated with L-1210 cells.
(15) Mice inoculated with tumor cells in the 10 NTX group had an acceleration (18%) in the latency of tumor appearance and, 2 weeks after cell inoculation, 70% of the mice in this group had tumors, in contrast to 10% of the controls.
(16) The viruses shed by the volunteers were indistinguishable from those with which they were inoculated.
(17) Precipitating antibodies were found in both lines; they first appeared 7 days after inoculation in P-line birds and 14 days after inoculation in N-line birds, but thereafter there was no difference between the two genetic lines.
(18) No histological changes in the intestines were observed in the fasted poults whereas definite lesions were observed in the BCDCV-inoculated poults.
(19) Cultures of these isolants were inoculated experimentally into turkeys and produced lesions of chlamydiosis that were indistinguishable from those caused by the strain originally recovered from diseases turkeys on the premises.
(20) Over a range of concentrations, DMD 368 produced 100% mortality while one Mel 3 strain, DMD 369, produced no mortality by 21 days after inoculation.
Vaccine
Definition:
(a.) Of or pertaining to cows; pertaining to, derived from, or caused by, vaccinia; as, vaccine virus; the vaccine disease.
(n.) The virus of vaccinia used in vaccination.
(n.) any preparation used to render an organism immune to some disease, by inducing or increasing the natural immunity mechanisms. Prior to 1995, such preparations usually contained killed organisms of the type for which immunity was desired, and sometimes used live organisms having attenuated virulence. since that date, preparations containing only specific antigenic portions of the pathogenic organism are also used, some of which are prepared by genetic engineering techniques.
Example Sentences:
(1) We were able to detect genetic recombination between vaccine strains of PRV following in vitro or in vivo coinoculation of 2 strains of PRV.
(2) Attempts are now being made to use this increased understanding to produce effective killed vaccines that produce immune responses in the lung.
(3) We have measured the antibody specificities to the two polysaccharides in sera from asymptomatic group C meningococcal carriers and vaccinated adults by a new enzyme-linked immunosorbent assay (ELISA) procedure using methylated human serum albumin for coating the group C polysaccharide onto microtiter plates.
(4) The simultaneous administration of the yellow fever vaccine did not influence the titre of agglutinins induced by the classic cholera vaccine.
(5) Before carrier vaccines are applied, these risks must be thoroughly evaluated case-by-case.
(6) Whole-virus vaccines prepared by Merck Sharp and Dohme (West Point, Pa.) and Merrell-National Laboratories (Cincinnati, Ohio) and subunit vaccines prepared by Parke, Davis and Company (Detroit, Mich.) and Wyeth Laboratories (Philadelphia, Pa.) were given intramuscularly in concentrations of 800, 400, or 200 chick cell-agglutinating units per dose.
(7) The prophylactic effect of immunization with P. aeruginosa polyvalent corpuscular vaccine has been shown on the model of P. aeruginosa generalized chronic infection in mice with leukopenia induced by the intraperitoneal injection of cyclophosphamids.
(8) The data support inclusion of these residues in future CS protein vaccines.
(9) By vaccinating adult dogs in boarding kennels the morbidity rate dropped from 83.5% to 6.5% and the mortality rate from 4.1% to 0.5%.
(10) It is clear that before general release of a new living feline infectious enteritis vaccine, there must be satisfactory evidence that concurrent infection will not affect the safety of the modified antigen.In cats infected with feline infectious enteritis there appears to be a short period, coinciding with the onset of leucopaenia, during which they are highly infectious.
(11) The combination vaccine consisted of 12 Lf tetanus toxoid and 10 TCID50 vaccinia virus "MVA" preserved with gelatine and glucosamine.
(12) We evaluated the safety and efficacy of a conjugate vaccine that links the H. influenzae type b capsular polysaccharide to the outer-membrane protein complex (OMPC) of Neisseria meningitidis serogroup B.
(13) The litter size of vaccinated gilts was larger than that of the control gilts.
(14) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
(15) The value of benefit-risk, benefit-cost, and cost-effectiveness analyses lies not in providing the definitive basis for a decision on vaccine use or evaluation.
(16) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
(17) For the purpose of studying the role of elastase and protease of Pseudomonas aeruginosa in bacterial infection in burns, the effects of the vaccines made from each enzyme, their toxoids and OEP on protection against infection in burned mice were studied.
(18) No vaccination reactions were noted, although most birds involved in the trials were carrying Mycoplasma spp.
(19) Serum from piglets of vaccinated sows had no more bactericidal activity than did sera from non-vaccinated sows.
(20) The purpose of this study was to investigate a tumor cell vaccine delivered via peripheral lymphatics as maintenance therapy after induction of remission with chemotherapy.