What's the difference between insalubrious and unwholesome?

Insalubrious

Definition:

(a.) Not salubrious or healthful; unwholesome; as, an insalubrious air or climate.

Example Sentences:

(1) The neighbourhood is extremely insalubrious, so this is not a place in which to wander about, and certainly not at night.
(2) In a time when the conditions of work were strikingly insalubrious, the etiological emphasis was on individual failure, not on physical or social conditions of work.
(3) But while the French government said there would be no change, there were signs that politicians on the right wanted to use the Brexit result to push for a renewed debate on the deal that has left thousands of migrants and refugees stuck at Calais in insalubrious and dangerous conditions in shanty camps.
(4) MacMillan subsisted on an insalubrious diet of alcohol, cigarettes, antidepressants and psychoanalysis – and yet still produced definitive works, including Manon, Elite Syncopations (a rare comedy) and Requiem.
(5) Police officers have avoided Lewisham for years, fearful of being asked to sign a petition On Silicon Roundabout , in central London’s insalubrious Old Street, there are people who spend all day on the internet, breaking from their secretive research only to communicate with friends on the encrypted radical hotbed known as Whatsapp .

Definition:

Example Sentences:

(1) That we demand a contest as satisfyingly unwholesome and rancorous as Cain and Abel, not something as nauseatingly wholesome and harmonious as Abel and Cole?
(2) In the southern forest areas, dried fish, groundnuts and oil palm products often carry unwholesome quantities of aflatoxin.
(3) In that sense all stories are written backwards - they are supposed to begin with the facts and develop from there, but in reality they begin with a journalist's point of view, a conception... All this is difficult and even rather unwholesome to explain to the layman, because he gets the impression that you are saying that truth does not matter and that you are publicly admitting what he long ago suspected, that journalism is a way of 'cooking' the facts.
(4) Clinicians must evaluate these systems as to their wholesome or unwholesome impact on a particular health issue or problem, seeking corrective as well as preventive measures.
(5) Like other unwholesome aspects of the Anthropocene, we mostly respond to mass extinction with stuplimity: the aesthetic experience in which astonishment is united with boredom, such that we overload on anxiety to the point of outrage-outage.
(6) The influence can be strong in lasting relationships; it can be either wholesome or unwholesome.