(a.) Not sensitive; wanting sensation, or wanting acute sensibility.
Example Sentences:
(1) In contrast, DNA polymerase alpha, the enzyme involved in chromosomal DNA replication, was relatively insensitive to CA1.
(2) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
(3) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(4) The mechanism by which K+ accumulates in the follicle was insensitive to ouabain, so that a typical Na+, K(+)-ATPase mechanism does not appear to be involved.
(5) All three organotins inhibited cardiac Na+,K(+)-ATPase, [3H]ouabain binding, K(+)-activated p-nitrophenyl phosphatase (K(+)-PNPPase) and oligomycin-sensitive (OS) and oligomycin-insensitive (OI) Mg(2+)-ATPase in a concentration-dependent manner.
(6) The most important causal factor, well illustrated by pressure studies, was the presence of a dynamic or static deformity leading to local areas of peak pressure on insensitive skin.
(7) However, blood with low HBeAg levels and free of detectable polymerase activity can still be infectious, since the polymerase reaction is rather insensitive compared to the radioimmunological HBeAg determination.
(8) For those synapses that were close to the soma the time constant for decay for the non-NMDA component, which was voltage insensitive, ranged from 4-8 ms. 7.
(9) A sharp decrease in oxygen uptake occurred in Neurospora crassa cells that were transferred from 30 degrees C to 45 degrees C, and the respiration that resumed later at 45 degrees C was cyanide-insensitive.
(10) The response amplitude is maximally sensitive to photons presented over durations of 30-45 min; is very insensitive to shorter light exposures; and is maintained with no evidence of adaptation over longer exposures.
(11) In contrast to the channel closing rate, the opening rate is relatively insensitive to voltage.
(12) By using pH- or Ca(2+)-sensitive dyes and recording at the ion-sensitive and -insensitive (isosbestic) wavelengths, the method can measure both cell volume changes and intracellular ionic activities.
(13) In patients with Cushing's disease or Nelson's syndrome ACTH secretion is insensitive to naloxone, presumably because of an autonomous pituitary adenoma or hypothalamic derangement.
(14) Compared to the controls, the vitamin E deprived animals were relatively insensitive to the effects of scopolamine.
(15) The chemical shifts of the C-2 proton of histidine 48 and of the C-4 proton of histidine 80, histidine residues that are close to one another and to another heterosaccharide side chain, show a similar insensitivity.
(16) Activity was insensitive to oxygen and CO if the substrates had no additional substituents on either ring or contained only electron-donating substituents.
(17) In some cases (approximately equal to 10%) the mechanism of androgen insensitivity could not be identified.
(18) We found the incorporated channels to be insensitive to calcium and octanol, and in most cases to pH in the range of 5-7, suggesting that either these agents do not interact directly with the junctional channels or that the corresponding gating regions are inactivated during the isolation and reconstitution procedures.
(19) The cattle filarial parasite Setaria digitata, a facultative anaerobe which is reported to be cyanide insensitive, lacks cytochromes and presents many unique characters.
(20) V0 estimates derived from the low load portion were positive and relatively insensitive to Ees.
Soulless
Definition:
(a.) Being without a soul, or without greatness or nobleness of mind; mean; spiritless.
Example Sentences:
(1) This looks like a soulless mass of concrete and glass that Soviet Russia made famous in their government buildings.
(2) The majority, however, are soulless, charmless glass boxes with no personality and, if not actively ugly, are not exactly beautiful either.
(3) "If you go there after dark, it is soulless," he said of the Westminster enclaves.
(4) If there was a fear before this Olympics began that it would be a corporatised, soulless event, the effort and enthusiasm of the volunteers have filled it with a likeably amateur and properly human warmth.
(5) Today it is pressed up against new office blocks in a rather soulless business district.
(6) The follow-up Glass Spider tour was castigated for its soulless over-production.
(7) The only entertainment within walking distance of E3 is LA Live – a sort of bar and restaurant theme park, an alcoholic Disneyland, which is precisely as soulless and desperate as it sounds.
(8) Despite the deaths of two brothers and his best friend, Amer said he felt content and liberated to have left behind the materialism and soullessness of a secular society.
(9) In his preening, know-it-all professional arrogance, Cruise thinks he's bulletproof, but the mouse roars, and the hitman pays (incidentally, when casting a soullessly efficient, emotionally unavailable professional, could there be a more perfect candidate than Cruise?).
(10) After Obama's re-election, Nugent said on Twitter: "Pimps whores & welfare brats & their soulless supporters have a president to destroy America."
(11) He was losing part-time jobs in call centres as fast as he could get them ("for wearing the wrong shoes, for telling the bosses they were soulless money-hungry pigs").
(12) Like journalism without grammar, the land without the family farm is meaningless, soulless, it goes to the core fabric of our nation,” he said.
(13) Comparisons between present-day China and the soulless, dreary totalitarian socialist state immortalised in Orwell's masterpiece are difficult to sustain after seeing clutch after clutch of Chinese teenagers, dressed in the latest quasi-Japanophile fashion, walk down a mobbed Beijing pedestrian shopping arcade nibbling at bouquets of candy floss and prattling on as if the phrase "commodity fetishism" had never crossed their young lips.
(14) This is an evil place, as airless and soulless as the inside of Pamela Geller’s head.
(15) Asked if Kilamba was somewhat soulless, he insisted: "It has character.
(16) It’s the unholy marriage of that soulless debate culture that works so well in Britain, transplanted to a nation with no social safety net and half a billion guns.
(17) The Baltimore city jail is a squalid, gray and soulless place.
(18) Now, he seems to be grudgingly continuing the impression , but his joy at the mocking the soullessness of the president-elect is clearly gone.
(19) Nehlen, like Trump, has railed against factory closures, promised to “repatriate” jobs to the US and branded Ryan a “soulless globalist”.
(20) The hospital is a sterile, soulless, modern unit and, visiting on a warm day, it’s a relief to escape to the garden outside.