(n.) The quality of being insolent; pride or haughtiness manifested in contemptuous and overbearing treatment of others; arrogant contempt; brutal impudence.
(n.) Insolent conduct or treatment; insult.
(v. t.) To insult.
Example Sentences:
(1) 50 runners with exertion induced injuries of the lower extremity were provided with appropriate running shoe insoles.
(2) And a woman in front of me said: “They are calling for Fox.” I didn’t know which booth to go to, then suddenly there was a man in front of me, heaving with weaponry, standing with his legs apart yelling: “No, not there, here!” I apologised politely and said I’d been buried in my book and he said: “What do you expect me to do, stand here while you finish it?” – very loudly and with shocking insolence.
(3) Subjects used these insoles during dance class for 15 weeks.
(4) Based on clinical and biomechanical peculiarities of foot, in the institute have been developed insertable orthopaedic devices for mass-produced footwear for mentioned pathology: corrective device with unloading element and curative insole.
(5) Young people now may hardly know her, and it is hard today to conjure up the sexiness, the daring, the insolence of some women on screen in the 50s when the Production Code still prevailed.
(6) The author discusses the use of accommodative weight-dispersing insoles as an alternative to surgical excision for the treatment of such lesions.
(7) Controlled rigidity is provided by the incorporation of a spring steel shank between the sponge insole and the hard wearing plastic sole.
(8) I was told it was a contractual requirement, despite there being no mention of either the strike system or the obligation to sell insoles within the contract itself.
(9) Therefore running shoe insoles can eliminate peak forces by exactly placing supporting elements.
(10) Treat with orthotic insoles or look at upping your shoe size.
(11) This paper describes a study of the effectiveness of commercially available shock absorbing insoles when used in four different pairs of shoes during normal walking.
(12) Insoles will be available to turn any existing shoes into smartshoes.
(13) A new method was developed for the quality testing of shoes, insoles and sport shoes.
(14) The purposes of this study were: 1) to compare the impact forces in running using running shoes with conventional insoles to the impact forces using running shoes with four different viscoelastic insoles, 2) to discuss possible effects of the viscoelastic insoles on lower leg kinematics, and 3) to explain the force and kinematic results using a mechanical model.
(15) A full account is given of (a) Wilhelm Werneck's therapeutic coagulations (1835): rupturing of cataract by focussed light (sun, phosphorus); (b) Maximilian Adolf Langenbeck's "insolation" of corneal, pupillary and retinal lesions and of traumatic cataract (1859); (c) Vinzenz Czerny's coagulation experiments on the retina of various animals (1867, 1882).
(16) Vertical foot bearing pressure was decreased by an average of 18% by wearing shoes padded with a Professional Protective Technology insole and the decrease was greater in patients with higher foot pressure.
(17) About a third of dancers fitted with viscoelastic insoles and a tenth of placebo insert wearers found that the insoles made their shoes too tight to be comfortable.
(18) Without physical exercise and direct insolation death usually occurred later (on the average of 5-9 days) from acute renal and renal-hepatic failure.
(19) The mechanism of the static effects of the wedged insole for the medial osteoarthritic knee was studied in ten women.
(20) The most important finding was that an elastic polymer insole with good shock absorbency properties did not prevent stress reactions of bone during a 12-week period of vigorous physical training.
Novel
Definition:
(a.) Of recent origin or introduction; not ancient; new; hence, out of the ordinary course; unusual; strange; surprising.
(a.) That which is new or unusual; a novelty.
(a.) News; fresh tidings.
(a.) A fictitious tale or narrative, professing to be conformed to real life; esp., one intended to exhibit the operation of the passions, and particularly of love.
(a.) A new or supplemental constitution. See the Note under Novel, a.
Example Sentences:
(1) Moreover in MIT-1, the size of the novel polypeptide was not that predicted of the precursor (44.9 kDa) but was about 39 kDa, the same size as the authentic GS gamma polypeptide in CYT-4.
(2) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(3) A novel prostaglandin E2 analogue, CL 115347, can be administered transdermally on a long-term basis.
(4) The lipid A moiety was shown to be responsible for this novel biological activity of the LPS molecule.
(5) Experiment 3 showed that the color-induced increase in odor intensity is not due to subjects' preexperimental experience with particular color-odor combinations, because the increase occurred with novel ones.
(6) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(7) But what they take for a witticism might very well be true; most of Ellis's novels tell more or less the same story, about the same alienated ennui, and maybe they really are nothing more than the fictionalised diaries of an unremarkably unhappy man.
(8) Cyclosporine is a fungal endecapeptide of novel chemical structure that causes preferential inhibition of T helper cells.
(9) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(10) Her novels have an enduring and universal appeal and she is recognised as one of the greatest writers in English literature.
(11) The complex problems have been successfully managed with novel guiding catheter shapes and ultralow profile balloons.
(12) Moreover, the most recent combined application of the rat interstitial cell testosterone (RICT) bioassay and a novel multiple-parameter deonvolution model has allowed investigators to dissect plasma concentration profiles of bioactive LH into defined secretory bursts, which have numerically explicit amplitudes, locations in time, and durations, and are acted upon by determinable subject- and study-specific endogenous metabolic clearance rates.
(13) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.
(14) This novel coumarin derivative significantly inhibited skin tumor initiation by DMBA in SENCAR mice when given at a dose of 200 nmol, 5 min (69% inhibition) or 24 h (76% inhibition) prior to initiation.
(15) Using a novel method for joining DNA sequences, we have exploited this difference between the two enzymes to identify the regions of the RT that contribute to the compounds' inhibitory activities.
(16) It may thus represent an artifact of the labeling procedure rather than a novel basophil-derived prostaglandin.
(17) Endothelin-1 (ET-1) is a novel vasoconstricting and cardiotonic peptide that is synthesized by the vascular endothelium.
(18) These observations indicated a novel mechanism that in the absence of light-dark schedule, mothers taught the circadian rhythm to the pups as they raised them.
(19) Pretreatment with a novel CRF antagonist, alpha-helical CRF9-41 (130.9 nmol i.t.v.
(20) Prions are novel, transmissible pathogens causing degenerative diseases of the central nervous system both in humans and in animals.