(a.) Not soluble; in capable or difficult of being dissolved, as by a liquid; as, chalk is insoluble in water.
(a.) Not to be solved or explained; insolvable; as, an insoluble doubt, question, or difficulty.
(a.) Strong.
Example Sentences:
(1) The samples are first disrupted by sonication and the insoluble proteins concentrated by high-speed centrifugation.
(2) The relationship between cold-insoluble complexes, or cryoglobulins, and renal disease was studied in rabbits with acute serum sickness produced with BSA.
(3) One cellulase is buffer-soluble, the other buffer-insoluble but extractable with high salt concentrations.
(4) Evidence is presented which suggests that these plasmid-mediated, temperature-inducible surface fibrillae are responsible for autoagglutination and are related to production of one prominent, Sarkosyl-insoluble polypeptide of ca.
(5) During the growth of Azotobacter vinelandii in batch culture in Burk's 2% glucose medium supplemented with 50 mg EDTA per litre, water-insoluble capsular polysaccaride material accumulated in cultures prior to the appearance of water-soluble polysaccharide in the culture medium.
(6) A Nonidet P 40 insoluble fraction was isolated from Trypanosoma brucei and was used to raise a monoclonal antibody (5E9).
(7) Insoluble collagen was found to bind electrostatically to chondromucoprotein.
(8) After 6 weeks irradiation, the insoluble collagen and elastin were both substantially elevated, as were the activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD).
(9) However, since the Krafft point of lincomycin palmitate is approximately 43 degrees, it does not form micelles below that temperature and appears to be quite insoluble until heated above 43 degrees.
(10) Average remnant diameters were 400-600 A and remnants were enriched in cholesteryl esters and in protein insoluble in tetramethylurea.
(11) Ultrastructural studies of detergent-insoluble cytoskeletons from infected cells and immunofluorescence microscopy of phalloidin-labeled cells showed alterations in the structure of the cytoskeleton during the internalization process including the accumulation of polymerized actin around entering bacteria.
(12) Cells obtained from 12-day tissue remained monolayers for 4 to 8 days, after which time portions of the culture contracted into matrix containing chemically definable insoluble elastin and forming desmosine cross-links.
(13) Micrococcal nuclease-digested testis and erythrocyte chromatin was separated into soluble and insoluble fractions.
(14) Five other patients with water-insoluble paraproteins were tested; two were clot-inhibitory.
(15) Both main-stream and side-stream cigarette smoke condensates and some fractions, containing water-soluble bases, water-insoluble bases, and polycyclic aromatic hydrocarbons, were found to induce AHH activity in lung and liver, the lung being induced to the greatest extent.
(16) The protein component was relatively insoluble and contained an excess of acidic over basic amino acids and little cystine.
(17) Biochemical analysis of the kinetics of assembly of two cytoplasmic plaque proteins of the desmosome, desmoplakins I (250,000 Mr) and II (215,000 Mr), in Madin-Darby canine kidney (MDCK) epithelial cells, demonstrated that these proteins exist in a soluble and insoluble pool, as defined by their extract ability in a Triton X-100 high salt buffer (CSK buffer).
(18) The ratio of soluble to insoluble beta-galactosidase decreased during the course of cell growth.
(19) GP Ib was sedimented with the Triton-insoluble actin filaments in trace amounts only, and only after high speed centrifugation (100,000 x g, 3 h).
(20) Elastic fibers have been shown to contain two proteins, insoluble elastin and the elastic fiber microfibril, a glycoprotein.
Unsolvable
Definition:
Example Sentences:
(1) Record linkage of the findings in heterozygotes for use later in life is an unsolved problem.
(2) Unsolved epidemics of acute respiratory disease dating to the 1950s were subsequently attributed to the newly described pathogens.
(3) The natural transmission mechanism(s) of the simian trypanosomiases in South Asia remains an unsolved problem.
(4) The role of steroid therapy in brain oedema following acute cerebral lesions is still unsolved.
(5) For each indicated educational--motivating unity parents have to be completely prepared for better and more complete than usual piling of facts and presenting in front of them unsolvable tasks and obligations.
(6) A number of problems concerning both clinical and genetic or cytogenetic aspects of the fragile-X syndrome remain unsolved.
(7) Examination of possibility of AAT deficiency should be performed in every case, where the cause of liver disease is unsolved; this examination is especially indicated by the presence of typical PAS positive, diastase-resistant, AAT immunreactive globules in hepatocytes.
(8) The attacks had clear echoes of the unsolved assassination in January this year of one of their colleagues, particle physicist Masoud Alimohammadi.
(9) The question, of whether long-term treatment of essential hypertension with angiotensin-converting enzyme (ACE) inhibitors is capable of modifying glucose tolerance or insulin sensitivity in Type 2 (non-insulin dependent) diabetes, is still unsolved.
(10) The problem of the quantification of vertigo is still unsolved.
(11) Although the molecular nature of several blood group antigens was established in 1950-1980, the identification and characteristics of the Rh-antigens long remained unsolved.
(12) Theoretical prediction of the structure, stability and activity of proteins, an important unsolved problem in molecular biology, would be of use for guiding site-directed mutagenesis and other protein-engineering techniques.
(13) Although implants have not yet been used for this purpose in children, there are no unsolvable technological problems.
(14) Coronary heart disease is now the leading cause of death in many countries and is the major unsolved problem in the treatment of hypertension.
(15) In January 1977 an unsolved outbreak of infection at St. Elizabeth's Hospital (Washington, D.C.) that occurred in 1965 was linked with Legionnaires' disease.
(16) Although the purely engineering problems as well as the surgical ones appear solvable at this time, the remaining unsolved problems lie in two areas: 1) the bioengineering interfacing, i.e., the search for methods needed to connect an engineering (electronic) device to the neural auditory system in an efficient manner; and 2) clinical tests for the assessment of the functional state of the cochlear nerve.
(17) The problem of its biological significance and the question whether emperipolesis is the result of invasion of engulfment must remain unsolved.
(18) These circulatory effects of O3 may be significant from the viewpoint of health effects, although its mechanisms remain unsolved.
(19) Its function, which has long been an unsolved puzzle, is likely to be related to the unique ability of PSII to oxidize water.
(20) So the problem of whether testosterone or androstanolone or another natural steroid is the most effective myotrophic hormone in rat skeletal muscle remains unsolved.