(n.) The quality or condition of being unstable; want of stability, firmness, or steadiness; liability to give way or to fail; insecurity; precariousness; as, the instability of a building.
(n.) Lack of determination of fixedness; inconstancy; fickleness; mutability; changeableness; as, instability of character, temper, custom, etc.
Example Sentences:
(1) (4) Despite the removal of the cruciate ligaments and capsulo-ligamentous slide, no significant residual instability was found in either plane.
(2) By measurement and analysis of the changes in carpal angles and joint spaces, carpal instability was discovered in 41 fractures, an incidence of 30.6%.
(3) Unrecognized flexion injuries of the cervical spine may lead to late instability and neurologic damage.
(4) Hypermobility and instability following injury and degenerative joint disease is poorly understood and often not recognized as the cause of the patients symptoms.
(5) In these three patients, laxity of the knee in flexion was so severe that posterior instability could not be corrected merely by patellar relocation.
(6) Cubitus valgus or instability due to a pseudarthrosis of the lateral epicondyle or to ligamentous injury may stretch the nerve.
(7) The hypothesis that this instability would lead to more errors and longer decision times for distinguishing left-right mirror-image figures was not supported.
(8) 93 knees in 74 patients between 9 and 20 years of age were operated because of patello-femoral instability.
(9) Whereas in flexion stress all methods showed a sufficient stability, the rotation tests proved, that in case of a dorsal instability of the lower cervical spine, posterior interlaminar wiring or anterior plate stabilization showed no reliable stabilization effect.
(10) There is a paucity of informative data on the potentially important role of specific sites of chromosomal instability in oncogenic processes.
(11) "In-gel renaturation" analysis did not show any DNA amplification of high degree in AT22IJE-T. Cytogenetic analysis showed considerable chromosomal instability in the new cell line, and medium conditioned by these cells contained the clastogenic activity which is characteristic of the parental strain as well.
(12) Instability or a return to violence could follow the imposition of measures that would threaten the ability of the PA to govern in the West Bank.
(13) This approach was used in 42 shoulders with rotator cuff tears or posterior instability without complications of infection, failure of deltoid healing, or compromise of suprascapular or axillary nerves.
(14) Sixteen patients who remained wet had detrusor instability; 9 of these were cured by anticholinergic medications.
(15) Atlantoaxial instability, defined as a gap of over 4 mm, was present in seven (10%) children and two (2%) adults.
(16) With these scores we expect to facilitate the diagnostic screening, to indicate the way of therapy and to avoid unnecessary surgery for urinary incontinence in cases of motor-urge-incontinence (detrusor instability, unstable bladder), as long as a urodynamic examination is not feasible on every incontinent women.
(17) Midcarpal instability occurs at the triquetral-hamate joint and is characterized by a dynamic subluxation of the joint.
(18) Structural instability of pZG1 could therefore be due at least in part to the presence of single-stranded DNA.
(19) Oxidative stress is now shown to occur in BS cells and may be responsible for the observed chromosomal instability.
(20) It is therefore unlikely that the tyrosinylation status directly affects the intrinsic stability of assembled microtubules since the rate of length redistribution is both a sensitive assay and a function of the kinetic parameters governing dynamic instability.
Lability
Definition:
(n.) Liability to lapse, err, or apostatize.
Example Sentences:
(1) Previous attempts to purify this enzyme from the liquid endosperm of kernels of Zea mays (sweet corn) were not entirely successful owing to the lability of partially purified preparations during column chromatography.
(2) EDRF is even more labile than prostacyclin, with a half-life of about 6 seconds, and it has recently been identified as nitric oxide.
(3) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(4) Bile flow was stimulated significantly by VPA and MCCA, but not by CCA; changes in bile flow correlated with the biliary excretion rate of base-labile conjugates rather than with excretion of the parent compounds themselves.
(5) Binding activity was labile to heat, and to treatment with pepsin or trypsin.
(6) The following factors were studied: relative ability to adsorb virus, sedimentation of the adsorbing components, heat lability of the components, virus elution, and recovery of cell-associated virus.
(7) Enzymatic lability does not, however, play as important a role as lipophilicity in the corneal and conjunctival penetration of cycloalkyl and aryl ester prodrugs.
(8) Brief digestion at neutral pH without reduction produced a molecule in which the Fab and Fc fragments were still linked by a pair of labile disulphide bridges, and the Fc fragment released by cleaving these bonds, called 1Fc fragment, contained a portion of the ;hinge' region including an interchain disulphide bridge.
(9) Detailed studies of the effects of acid pH on the formation of Fraction C after borohydride reduction demonstrated the apparent lability of the non-reduced form, thus confirming our previous findings (Bailey & Lister, 1968).
(10) A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.
(11) In 13 (26%) inpatients and 11 (49%) outpatients Shigella was found, and heat-labile and heat-stable forms of enterotoxigenic Escherichia coli were found in 9 (18%) inpatients and 1 (4%) outpatient.
(12) The factor appears to rearrange the distribution of myotube AcCho receptors either by aggregating mobile AcCho receptors or by stabilizing labile receptor aggregates.
(13) The transformation-related protein p53 is normally very labile.
(14) The results are consistent with an action of banana tree juice on the molecule responsible for excitation-contraction coupling in skeletal muscle, resulting in a labilization of intracellular Ca2+.
(15) It was determined by mouse protection tests that the specificity of protective antibodies was directed toward a trypsin labile antigen.
(16) Twelve days following discontinuation of the drug, the patient continued to experience diarrhea, restlessness, emotional lability, and anxiety.
(17) Cytokine secretion by activated lymphocytes or mast cells is preceded by dramatic stabilization of the normally labile GM-CSF mRNA.
(18) (i) The secretions of most of the deep cells and the majority of superficial cells contained sialidase-labile and sialidase-resistant sialomucins.
(19) The studies reported here demonstrate the presence of heat-labile serum factors in normal human sera which killed B. fragilis directly and which promote its phagocytosis and killing by PMNs.
(20) High blood pressure is itself an independent risk factor for vascular disease, in proportion to its height, for all ages and sexes, whether systolic or diastolic, labile or fixed, and the threat is further aggravated by surges in blood pressure throughout the person's daily activities.