What's the difference between instead and substitute?

Instead


Definition:

  • (adv.) In the place or room; -- usually followed by of.
  • (adv.) Equivalent; equal to; -- usually with of.

Example Sentences:

  • (1) There is no evidence that health-maintenance organizations reduce admissions in discretionary or "unnecessary" categories; instead, the data suggest lower admission rates across the board.
  • (2) Maybe the world economy goes tits up again, only this time we punish the rich instead of the poor.
  • (3) Instead, the White House opted for a low-key approach, publishing a blogpost profiling Trinace Edwards, a brain-tumour victim who recently discovered she was eligible for Medicaid coverage.
  • (4) Keep it in the ground campaign Though they draw on completely different archives, leaked documents, and interviews with ex-employees, they reach the same damning conclusion: Exxon knew all that there was to know about climate change decades ago, and instead of alerting the rest of us denied the science and obstructed the politics of global warming.
  • (5) Instead of later renal failure and, of course, mental retardation, it was the histological features of the fetus eyes which permit to diagnose and exhibit both congenital cataract and irido-corneal angle dysgenesis.
  • (6) It was recently demonstrated that MRL-lpr lymphoid cells transferred into lethally irradiated MRL- +mice unexpectedly failed to induce the early onset of lupus syndrome and massive lymphadenopathy of the donor, instead they caused a severe wasting syndrome resembling graft-vs-host (GvH) disease.
  • (7) The size of Florida makes the kind of face-to-face politics of the earlier contests impossible, requiring instead huge ad spending.
  • (8) Instead, he handed over the opening to reporter Molly Line, who said, “Racial profiling is in the eye of the beholder,” before citing differing perceptions of the phenomenon between white and black people, which is like reading the headline “Rapist, Victim Differ on Consent”.
  • (9) It is intended to aid in finding the appropriate PI (proportional-integral) controller settings by means of computer simulation instead of real experiments with the system.
  • (10) Urban hives boom could be 'bad for bees' What happened: Two professors from a University of Sussex laboratory are urging wannabe-urban beekeepers to consider planting more flowers instead of taking up the increasingly popular hobby.
  • (11) Furthermore, even the action of Lys-5 on the Pseudomonas OM was abolished when the assays were performed in the presence of 150 mM NaCl instead of the low-ionic strength buffer earlier used by investigators studying the effect of polycations on the Pseudomonas OM.
  • (12) Instead, we suffer sporadic exhibitions, which they call consultation.
  • (13) Instead of healing the nation after a fractious referendum he inflamed the situation.
  • (14) Instead, an antiarrhythmic drug should be administered and another shock of the same intensity that defibrillated the first time should be applied.
  • (15) When rabbit and horse sera were used instead of human serum for cultivation, in both groups the share of positive cultures increased and more large forms of B. hominis cells were observed.
  • (16) Instead, they say, we should only eat plenty of lean meat and fish, with fruit and raw vegetables on the side.
  • (17) Orbital hypertelorism, strictly defined as an increase in bony interorbital distance, is not itself an isolated syndrome, but is instead an anomaly that may occur as either part of a syndrome or malformation sequence.
  • (18) She said the rise in fees was not part of the effort to tackle the deficit, but was instead about Clegg "going along with Tory plans to shove the cost of higher education on to students and their families".
  • (19) When my form teacher said I’d worked well in every subject except geography, I made her change the bit that said I’d not tried to say, instead, that I was rubbish at it.
  • (20) Instead, a repetitive, stepwise dissolution pattern was observed.

Substitute


Definition:

  • (n.) One who, or that which, is substituted or put in the place of another; one who acts for another; that which stands in lieu of something else
  • (n.) a person who enlists for military service in the place of a conscript or drafted man.
  • (n.) To put in the place of another person or thing; to exchange.

Example Sentences:

  • (1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
  • (2) In the clinical trials in which there was complete substitution of fat-modified ruminant foods for conventional ruminant products the fall in serum cholesterol was approximately 10%.
  • (3) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
  • (4) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
  • (5) The resonance Raman spectra of oxy and deoxy cobalt-substituted hemoglobin (CoHb) are reported.
  • (6) The most important conclusion of both conferences was that oestrogen substitution can significantly reduce the incidence of fractures in postmenopausal women.
  • (7) S-methyl-l-cysteine, 2-hydroxy-4-methiol butyric acid, S-adenosyl-l-methionine, and methionine peptides were the only compounds supporting growth, when substituted for methionine.
  • (8) This implies that the epitope(s) of NNA-PLA2 might comprise some substituted residues in the sequence of PLA2 homologues.
  • (9) The deletions and substitutions appear to occur in separate molecules.
  • (10) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
  • (11) N-Methoxysulphonamides showed no inhibitory activity, as predicted by the classic work of Krebs on N-substituted inhibitors.
  • (12) Substitution of NaCl in the extracellular medium by sucrose, LiCl, or Na2SO4 had no effect on glutamate stimulation of [3H]dopamine release; however, release was inhibited when NaCl was replaced by choline chloride or N-methyl-D-glucamine HCl.
  • (13) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
  • (14) Substitutes: Andoni Zubizarreta (Spain), Lajos Detari (Hungary), Dragan Stojkovic (Yugoslavia), Igor Belanov (USSR), Preben Elkjær Larsen (Denmark), Lars Larsson (Sweden), Alexandre Zavarov (USSR).
  • (15) Lipoprotein concentrations reverted to normal after substitution with thyroxine (T4) until the euthyroid state was reached.
  • (16) Taken together with our previous studies showing that MDMA substitutes for the phenylisopropylamine stimulant (+)amphetamine, but that neither MDE nor N-OH MDA substitute for (+)amphetamine or for the phenylisopropylamine hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), the present results [i.e., MDMA-stimulus generalization to MDE, N-OH MDA, but not to (+)amphetamine] suggest that 1) MDMA produces effects other than those that may be considered amphetamine-like, and 2) MDE and N-OH MDA are MDMA-like agents with even less of an amphetamine-like component of action than MDMA itself.
  • (17) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
  • (18) Substitution of DnaK protein with that of the mutant DnaK756 protein blocks lambda P release.
  • (19) To selectively stain polyanionic macromolecules of growth plate cartilage and to prevent artifacts induced by aqueous fixation, proximal tibial growth plates were excised from rats, slam-frozen, and freeze-substituted in 100% methanol containing the cationic dye Alcian blue.
  • (20) Plasma drug concentrations, subjective self-ratings, and the digit symbol substitution test (DSST) were evaluated during 24 hours after dosage.