What's the difference between instigate and irritate?

Instigate


Definition:

  • (v. t.) To goad or urge forward; to set on; to provoke; to incite; -- used chiefly with reference to evil actions; as to instigate one to a crime.

Example Sentences:

  • (1) He said he will pursue new measures, including demolishing the homes of instigators.
  • (2) The dazzling Deulofeu was the instigator of the first.
  • (3) In a majority of the cases electro-acupuncture was found to be effective, and this treatment should be instigated as early as possible.
  • (4) The move, first mooted two months ago, has been instigated with Jol's blessing and the new man was quick to insist he had spent "many hours" talking with his compatriot prior to accepting the position, even if his arrival effectively dilutes the manager's powerbase at the club.
  • (5) Murdoch has instigated a series of cost-cutting measures in newspapers in London, New York and Sydney as part of financial restructuring ahead of the de-merger.
  • (6) Mustafa's defence was that he watched police officers plant the weapon during a search of the flat and, when he demanded to know why they were doing it, he was told it was at the instigation of British authorities.
  • (7) Die Mannschaft were eliminated in the group stage that year, a failure that instigated a major revamp of the nation’s academy system.
  • (8) The man who renounced Australia Read more It was “not so much a defence to the charges [but] a negotiating point or olive branch” held out to the commonwealth to instigate discussion towards a treaty and formal consent for its occupation of the land, he said.
  • (9) She writes: Reassurances from the US that short-term measures will be instigated to avert the upcoming debt-ceiling deadline have given European equity markets a jolt upwards, helping to stem some of the risk aversion of the past few days.
  • (10) Pediatricians are important instigators of behavior change for the promotion of nonsmoking.
  • (11) The striking similarity between virtual and real effects in this respect is best explained in terms of physiological border perception processes, possibly instigated by a cognitive mechanism.
  • (12) The task was designed in an attempt to isolate (a) frustration from attack as the instigator of aggression and (b) instrumental from hostile aggression as the desired outcome.
  • (13) Tony Abbott on Sunday announced he would instigate a “root and branch” review of the parliamentary entitlements system, following the resignation of embattled speaker Bronwyn Bishop .
  • (14) Retrospective analysis of the validity and application of these experimental data and consideration of the problems related to precipitation of magnesium salts in "intracellular" perfusates has instigated investigation related to the necessity of including this ingredient in our previously described hyperosmolar intracellular electrolyte solutions.
  • (15) At the Hague conference, instigated at Washington's request to rally international support for Obama's new strategy in Afghanistan, Finland's foreign minister, Alexander Stubb, called on the Karzai government to respond to the Guardian report, a call echoed by Iceland, while Norway also expressed concern over the trend in women's rights.
  • (16) Jang Song-thaek, previously one of the country's most powerful men, was accused of everything from plotting to overthrow the state to instigating disastrous currency reforms and dishing out pornography in the report from official news agency KCNA.
  • (17) The results support the contention that ionizing radiation instigates alterations in the dynamic permeability of membranes, allowing leakage of biologically active material out of the injured cell.
  • (18) She said she inherited the arrangement when she joined the bank, adding: "At my instigation ... the model is being actively reviewed."
  • (19) The letter followed a pledge in February by hundreds of artists and musicians to instigate a cultural boycott of Israel due to the country’s “unrelenting attack on [Palestinian] land, their livelihood, their right to political existence”.
  • (20) Falconer said: "What schedule 7 allows an examining officer to do is to question somebody in order to determine whether he is somebody who is preparing, instigating or commissioning terrorism.

Irritate


Definition:

  • (v. t.) To render null and void.
  • (v. t.) To increase the action or violence of; to heighten excitement in; to intensify; to stimulate.
  • (v. t.) To excite anger or displeasure in; to provoke; to tease; to exasperate; to annoy; to vex; as, the insolence of a tyrant irritates his subjects.
  • (v. t.) To produce irritation in; to stimulate; to cause to contract. See Irritation, n., 2.
  • (n.) To make morbidly excitable, or oversensitive; to fret; as, the skin is irritated by friction; to irritate a wound by a coarse bandage.
  • (a.) Excited; heightened.

Example Sentences:

  • (1) Postpartum management is directed toward decreasing vasospasm and central nervous system irritability and maintaining fluid and electrolyte balance.
  • (2) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
  • (3) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
  • (4) Inhibition of binding of [3H]TPA to the receptor preparation by tigliane and ingenane DTE correlates with irritant activity in vivo, while some daphnane and 1 alpha-alkyldaphnane DTE inhibit binding of [3H]TPA in a less pronounced manner but still are very irritant.
  • (5) Exposure to irritants was also more common among the asthmatics than the nonasthmatics with similar exposure to organic allergens (P = 0.004).
  • (6) The purpose of this study was to develop a new model for the induction of chronic irritant contact dermatitis, which would reflect well the conditions of daily practice.
  • (7) The drug I started taking caused an irritating, chronic cough, which disappeared when I switched to an inexpensive diuretic.
  • (8) These injections led to epidermal hyperplasia in areas overlying the irritant and the effect was most significant when the irritant was placed in the upper dermis.
  • (9) Two children required lidocaine therapy for cardiac irritability manifesting as multifocal PVCs and ventricular tachycardia.
  • (10) In autumn, leaf-heaps composted themselves on sunken patios, and were shovelled up by irritated owners of basement flats.
  • (11) The dietary fibre intake of 25 patients with the irritable bowel syndrome was assessed by dietary recall over one week for the period before onset of symptoms, at diagnosis and after six months treatment with bran and a fibre-rich diet, and compared with controls matched for age and sex.
  • (12) A case of epidermoid tumor of the sacral area with S3 root irritation resulting in bladder dysfunction is presented and its possible relationship to spinal puncture is discussed.
  • (13) The present study did not identify any baseline parameters such as initial prostate volume, peak flow rates, or obstructive or irritative symptom scores that correlated with clinical outcome.
  • (14) Scores on the "dependent smoking" subscale of the smoking motivation questionnaire correlated significantly with overall withdrawal severity, craving, and increased irritability.
  • (15) The airways can be affected by inflammation, can be targets of infection, and can respond to chemical irritants with bronchoconstrictive responses.
  • (16) Some pulp irritation can occur if deep restorations are not placed over a protective film.
  • (17) MIDAZOLAM IS SUPERIOR TO DIAZEPAM IN CERTAIN WAYS: it has a more rapid onset; produces greater anterograde amnesia, less postoperative drowsiness, less venous irritation and less likelihood of thrombophlebitis development.
  • (18) Primary invasive adenocarcinoma of the bladder was diagnosed in a fifty-two-year-old male with a two-month history of irritative voiding symptoms.
  • (19) We studied seventy patients, 23 males and 47 females with irritable bowel syndrome in adolescence aged 13-19 yrs, who visited the department of psychosomatic medicine in Takano Hospital during about six year period of April, 1986-July, 1992.
  • (20) The study suggested that 1) diabetes and "prediabetes" produce significant changes in levels of chondroitin 4, 6, and dermatan sulfates within alveolar bone, 2) in "prediabetic" animals, interdental bone loss occurs prior to the onset of clinical symptoms and in the absence of local irritating factors, the bone height appears to return to normal levels, and 3) there may be a correlation between alveolar bone height and relative levels of dermatan sulfate.