(1) Light microscopic studies of pancreata from mice sacrificed at this time demonstrated insulitis and beta cell necrosis.
(2) The incidence and severity of insulitis was linked to MHC but no influence of TCR genes on insulitis nor an association between insulitis and antipolar antibodies could be demonstrated in this study.
(3) BB rats develop both pancreatic insulitis and lymphocytic thyroiditis, but whereas spontaneous autoimmune diabetes is common, hypothyroidism is rare.
(4) A grassed roof, solar panels to provide hot water, a small lake to catch rainwater which is then recycled, timber cladding for insulation ... even the pitch and floodlights are "deliberately positioned below the level of the surrounding terrain in order to reduce noise and light pollution for the neighbouring population".
(5) Called arctic packs, the insulating material consists of crude oil or diesel fuel.
(6) Matthew Fuller, 25, Rueben Barnes, 16, and Mitchell Sweeney, 22, died from electrocution and Marcus Wilson, 19, died after installing insulation batts in extreme heat.
(7) It found that on average, loft insulation decreases home gas consumption by 1.7%, cavity wall insulation by 7.8% and a new boiler by 9.2% (median figures were slightly higher).
(8) Heterozygosity for H-2nod was permissive for the development of pancreatic interstitial inflammation and peri-islet insulitis, whereas homozygosity for H-2nod was highly associated with insulitis.
(9) The probe tip was a gold-plated pin, insulated from the saliva by soft wax.
(10) "We quickly added cavity wall insulation which warmed the house, and fitted low-energy light bulbs in most rooms, reducing our electricity bill.
(11) Nicotinamide, a vitamin B group substance, has previously been shown to prevent diabetes and suppress insulitis in the NOD mouse.
(12) The NOD (non-obese diabetic) mouse spontaneously develops insulin-dependent diabetes mellitus (IDDM) characterized by autoimmune insulitis, involving lymphocytic infiltration around and into the islets followed by pancreatic beta (beta) cell destruction, similar to human IDDM.
(13) New laws may be needed to force private landlords to insulate and upgrade rented homes, the report says.
(14) Composite resin restoration of posterior teeth necessitates a reassessment of cavity insulation and dentine conditioning.
(15) "Before this scheme rolled out I think there were very few accidents in the insulation industry," said the commissioner, Ian Hanger QC, adding that problems occurred after an influx of people becoming installers, including a number of "shonks".
(16) Treatment with IL-1 alpha also inhibited insulitis and hyperglycemia induced by adoptive transfer of pathogenic, polyclonal CD4+8- T cells.
(17) In conclusion, there is a reasonable chance that retirement plan assets in Delaware qualified plans are insulated from judgment creditors, but the best course is to maintain adequate insurance protection and follow an aggressive prejudgment strategy in serious cases so you don't have to resolve the issue in a bankruptcy proceeding.
(18) The incidence of insulation break in this polyurethane unipolar electrode is uncommon and occurs at further stress points.
(19) Subsequent histological examination of pancreatic tissues revealed that autoimmune insulitis was prevented in E alpha d backcross and transgenic mice but not in A beta k transgenic mice.
(20) These results confirmed the presence of type C retrovirus in non-obese diabetic mouse Beta cells and suggest a role for retrovirus in the development of insulitis and diabetes in these mice.
Insulting
Definition:
(p. pr. & vb. n.) of Insult
(a.) Containing, or characterized by, insult or abuse; tending to insult or affront; as, insulting language, treatment, etc.
Example Sentences:
(1) The variation of the activity of the peptidase with pH in the presence of various inhibitors was investigated in both control and insulted muscle fibres.
(2) To study these changes more thoroughly, specific monoclonal antibodies of the A and B subunits of calcineurin (protein phosphatase 2B) were raised, and regional alterations in the immunoreactivity of calcineurin in the rat hippocampus were investigated after a transient forebrain ischemic insult causing selective and delayed hippocampal CA1 pyramidal cell damage.
(3) Histopathological studies confirmed that mice fed 933cu-rev died from bilateral renal cortical tubular necrosis consistent with toxic insult, perhaps due to Shiga-like toxins.
(4) Combined with histological analysis, these results suggest a more rapid recovery of normal spermatogenesis after physical insult with LAC treatment.
(5) Mark Latham's insights, insults and feuds are why he's worth reading | Gay Alcorn Read more BuzzFeed political editor Mark Di Stefano, the reporter who broke the story linking Latham to the less-than-savoury @RealMarkLatham Twitter account , had been chasing Stutchbury for days.
(6) Among the various physiological factors involved in the development of a nephrotoxic insult, certain renal transport systems may be important.
(7) In addition, PROM is the result of direct bacterial insults or host-mediated autodestruction in response to bacterial presence or challenge.
(8) Postmortem biochemical indices may provide a useful adjunct to morphological studies in the identification of antemortem brain insult.
(9) This toxic effect, although not seen in intact nigrostriatal systems, may indicate L-dopa toxicity on transplanted DA cells, or on DA cells maximally activated to recover from insult.
(10) Under the conditions employed in these studies, repeated occlusions give rise to progressively more prolonged deficits in brain protein synthesis activity, which may thus provide a useful index of the severity of the accumulated ischemic insult.
(11) The loss of coronary reserve was less than that previously observed after a 15-min occlusion, suggesting that the magnitude of the postischemic vascular abnormalities increases with the duration of the ischemic insult.
(12) We also observed a difference in the pattern and severity of alterations between repeated ischemic insults and single ischemia.
(13) Unconsciousness was associated with a brief period of hypotension, so brief that in itself it caused no apparent insult.
(14) These findings suggest that NB-818 may be useful for clinical treatment of neurological deficit after an ischemic insult.
(15) For example, patients suffering from transfusion-related acute lung injury (TRALI) experience onset of insult within 6 hours of a transfusion and have the presence of leukoagglutinins in their serum.
(16) This review article discusses the clinical manifestations and the diagnostic workup of insults to the kidney in patients with cancer.
(17) We have recently demonstrated in vitro a potential biological mechanism which could occur in vivo upon inhaling airborne graon dust, thereby constituting a potential inflammatory insult to the respiratory tracts of grain workers.
(18) It is hypothesized that transmission failure of interneuronal systems in the initial period following insult may be a general response occurring in wide areas of the central nervous system, and not restricted to areas to which mechanical stress is directly applied.
(19) These shape changes may become irreversible and, in fact, they may be encountered in different types of haemolytic disease, suggesting that the echinocytic and stomatocytic shape changes represent two fundamental ways in which red cells react to intrinsic and extrinsic insults.
(20) The Labour party erupted into open civil war as Ed Miliband loyalists and supporters of Johann Lamont, the Scottish Labour leader who resigned this weekend, exchanged accusations and insults.