(a.) Containing, or characterized by, insult or abuse; tending to insult or affront; as, insulting language, treatment, etc.
Example Sentences:
(1) The variation of the activity of the peptidase with pH in the presence of various inhibitors was investigated in both control and insulted muscle fibres.
(2) To study these changes more thoroughly, specific monoclonal antibodies of the A and B subunits of calcineurin (protein phosphatase 2B) were raised, and regional alterations in the immunoreactivity of calcineurin in the rat hippocampus were investigated after a transient forebrain ischemic insult causing selective and delayed hippocampal CA1 pyramidal cell damage.
(3) Histopathological studies confirmed that mice fed 933cu-rev died from bilateral renal cortical tubular necrosis consistent with toxic insult, perhaps due to Shiga-like toxins.
(4) Combined with histological analysis, these results suggest a more rapid recovery of normal spermatogenesis after physical insult with LAC treatment.
(5) Mark Latham's insights, insults and feuds are why he's worth reading | Gay Alcorn Read more BuzzFeed political editor Mark Di Stefano, the reporter who broke the story linking Latham to the less-than-savoury @RealMarkLatham Twitter account , had been chasing Stutchbury for days.
(6) Among the various physiological factors involved in the development of a nephrotoxic insult, certain renal transport systems may be important.
(7) In addition, PROM is the result of direct bacterial insults or host-mediated autodestruction in response to bacterial presence or challenge.
(8) Postmortem biochemical indices may provide a useful adjunct to morphological studies in the identification of antemortem brain insult.
(9) This toxic effect, although not seen in intact nigrostriatal systems, may indicate L-dopa toxicity on transplanted DA cells, or on DA cells maximally activated to recover from insult.
(10) Under the conditions employed in these studies, repeated occlusions give rise to progressively more prolonged deficits in brain protein synthesis activity, which may thus provide a useful index of the severity of the accumulated ischemic insult.
(11) The loss of coronary reserve was less than that previously observed after a 15-min occlusion, suggesting that the magnitude of the postischemic vascular abnormalities increases with the duration of the ischemic insult.
(12) We also observed a difference in the pattern and severity of alterations between repeated ischemic insults and single ischemia.
(13) Unconsciousness was associated with a brief period of hypotension, so brief that in itself it caused no apparent insult.
(14) These findings suggest that NB-818 may be useful for clinical treatment of neurological deficit after an ischemic insult.
(15) For example, patients suffering from transfusion-related acute lung injury (TRALI) experience onset of insult within 6 hours of a transfusion and have the presence of leukoagglutinins in their serum.
(16) This review article discusses the clinical manifestations and the diagnostic workup of insults to the kidney in patients with cancer.
(17) We have recently demonstrated in vitro a potential biological mechanism which could occur in vivo upon inhaling airborne graon dust, thereby constituting a potential inflammatory insult to the respiratory tracts of grain workers.
(18) It is hypothesized that transmission failure of interneuronal systems in the initial period following insult may be a general response occurring in wide areas of the central nervous system, and not restricted to areas to which mechanical stress is directly applied.
(19) These shape changes may become irreversible and, in fact, they may be encountered in different types of haemolytic disease, suggesting that the echinocytic and stomatocytic shape changes represent two fundamental ways in which red cells react to intrinsic and extrinsic insults.
(20) The Labour party erupted into open civil war as Ed Miliband loyalists and supporters of Johann Lamont, the Scottish Labour leader who resigned this weekend, exchanged accusations and insults.
Tactless
Definition:
(a.) Destitute of tact.
Example Sentences:
(1) "I haven't done years of diversity training, so sometimes I say things which are probably tactless, and I don't mean to, to be honest, I don't mean to do that.
(2) There was one sticky moment, when Mr Cameron was reminded by a tactless journalist that he had once described his new coalition partner as "my favourite political joke".
(3) Jean-Paul Corap, an artist, felt the tweet was tactless.
(4) Little wonder that tactless buyers at Asda rubber-stamped the rapidly withdrawn "Mental Patient" fancy dress costume when "mental" is routinely worn as a badge of gregarious honour.
(5) the physician-originated spread of "shipyard eye," tactless behavior toward patients, and lapses in malaria eradication programs.
(6) Little, Will Mellor, Natalie Casey and Sheridan Smith may be the bigger names, but Louise is the comic genius - needy, self-obsessed and tactless to the point of psychopathology.
(7) All kinds of petty discomforts – overcrowded rooms, long hours, arbitrary or tactless treatment – were overlooked in the general sense of adventure, progress, and public service.
(8) I ask if she still listens to the show, and get the most comically tactless answer: “No, I don’t.
(9) Last year he managed to stir up a massive row over a long-dead economist when he suggested that John Maynard Keynes had no stake in the future because he was gay and childless – although he did later apologise, calling his remarks "stupid and tactless".
(10) A tactless candidate was another problem: Maria Hutchings came across as more Ukip and less Conservative than Ukip's own smooth-talking Diane James.
(11) It is true that there has been some tactless western patronising along the way.
(12) Though foreign media highlighted Berlusconi's characteristically tactless remark that the homeless should think of themselves as being on a "camping weekend", his slip was barely reported in Italy itself.
(13) In 2003, he headbutted a policeman in a Paris casino rumpus and was subsequently fined and given a suspended jail term, tactlessly telling the press that to assault a cop was “the dream of every Frenchman”.
(14) The rant about late payments was many things: unprofessional, relentless, vitriolic when he dealt with listeners telling him to stop moaning, self-indulgent, and tactless with a young audience who will be feeling the effects of the recession more acutely than many other radio audiences.
(15) David Cameron's team, alas, seem to specialise in snoozing, sloppy pizza and total tactlessness – and nothing will ever be properly regulated that way.
(16) I fell asleep in front of Mamma Mia!, a show the teenage me found entirely baffling and geared towards, as I explained tactlessly to my mother, "women of a certain age".