(a.) Incapable of being passed over, surmounted, or overcome; insuperable; as, insurmountable difficulty or obstacle.
Example Sentences:
(1) Residual technical problems remain which should not prove insurmountable.
(2) It presents a challenge, but not an insurmountable one.
(3) They serve only to create insurmountable barriers that effectively eliminate medical abortions as an available option."
(4) The following myths are discussed and refuted: (1) There is an insurmountable community-research chasm.
(5) This speech was designed to allow progressives once again to see Barack Obama as they have always wanted to see him, his policies notwithstanding: as a deeply thoughtful, moral, complex leader who is doing his level best, despite often insurmountable obstacles, to bring about all those Good Things that progressives thought they would be getting when they empowered him.
(6) loxtidine and lamitidine, are insurmountable H2-receptor blockers.
(7) The challenges sometimes feel insurmountable, Tousif says.
(8) David Cameron is preparing to bow to insurmountable political opposition by putting the coalition's flagship NHS reform bill on hold beyond Easter, and possibly for as long as three months.
(9) In the pithed rat, EXP3892 showed selective and insurmountable AII antagonism.
(10) Recent data suggest that hyperacute rejection may not represent an insurmountable barrier to discordant xenotransplantation.
(11) The scale and depth of the climate challenge may seem insurmountable, and politicians will tell us with no irony, that they cannot sell, and no one will buy the policy ticket necessary for our own environmental rescue.
(12) The study of agonist-antagonist interactions may be aided by the use of these procedures, as descriptions of insurmountable antagonism may be complemented by the identification of stimulus conditions associated with the antagonist, as well as those conditions that represent novel stimulus states.
(13) The authors conclude that though the process to primary mental health care will be a long one, the problems are unlikely to be insurmountable.
(14) No insurmountable problems in the development of the artificial heart have been identified.
(15) The reliance on scientific evidence appears to present almost insurmountable problems of proof of causation to the plaintiff.
(16) That problem might not have been insurmountable had it presented itself at another point in our history.
(17) In one case, a further increase in buspirone dose resulted in an insurmountable antagonism, i.e., increasing APO dose still resulted in primarily saline-appropriate responding.
(18) Taken together, these results show that GRI17289 is a potent, specific, selective and insurmountable antagonist at angiotensin AT, receptors.
(19) But if Pope Francis has his way, a deal to bridge what many believe is an insurmountable divide between the Roman Catholic church and the communist Chinese government could be announced within the next 30 days.
(20) Shareable cities These may seem like fairly insurmountable obstacles.
Overwhelming
Definition:
(p. pr. & vb. n.) of Overwhelm
(a.) Overpowering; irresistible.
Example Sentences:
(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) She added: “We will continue to act upon the overwhelming majority view of our shareholders.” The vote was the second year running Ryanair had suffered a rebellion on pay.
(3) T cells admixed in the germinal centers were overwhelmingly of the T-helper type.
(4) Unfortunately for the governor, he could win both states and still face the overwhelming likelihood of failure if he doesn't take Ohio, where the poll found Obama out front 51-43.
(5) In Britain, the European election is overwhelmingly seen through the prism of domestic politics.
(6) Photograph: Christopher Thomond for the Guardian Asked if Watson should seek to refresh his mandate after Corbyn’s overwhelming victory among members, McCluskey added: “Well, if Tom wants to try to refresh his mandate it would be interesting to see what happens.” Watson said it was time “to be proud of our party”, because the Conservatives were beatable and the prime minister, Theresa May, could call an election any time.
(7) The government acknowledged it had been overwhelmed by the devastation from the deadliest quake in Nepal in over 80 years.
(8) He made me laugh and cry, and his courage in writing about what he was going through was sometimes quite overwhelming.
(9) Although alpha 1-antiprotease (alpha 1-AP) binds and inactivates NE and is the major antielastase of the lower respiratory tract, antielastase defenses may be overwhelmed in CF, leading to progressive lung damage.
(10) And HAP has shown that the key finding that debt slows growth was driven overwhelmingly by the exclusion of four years of data from New Zealand.
(11) Cathepsin D-like acid proteinase existed overwhelmingly in the mucosal layer and was hardly detected in the gastric juice.
(12) Hence, reaction of chemical carcinogen with nuclear DNA is possible only when the cell is overwhelmed leading to cell death, or following a temporary breach of the nuclear membrane control points, but the DNA damage in the latter is totally reparable.
(13) The facts are clear: the overwhelming majority of EU citizens in Britain are contributors, not freeloaders.” But that was not the official position of any of the parties involved, so it went mostly unsaid.
(14) Of 54 patients with poor-grade aneurysms, ventriculostomy was placed in 47 (87.0%) and yielded high ICP's in the overwhelming majority, with the mean ICP being 40.2 cm H2O.
(15) There is overwhelming evidence, today, that such factors are involved in the manifestation of acute as well as chronic, non-specific as well as well as specific inflammation.
(16) Mobile phone networks, overwhelmed by demand, were down for hours, with authorities advising people to use email or text messages instead.
(17) The immunity was enacted by an overwhelming bipartisan vote, with the support of leading Democrats including Barack Obama, who had promised - when seeking his party's nomination - to filibuster any bill that contained retroactive telecom immunity.
(18) There’s an overwhelming sadness among kids like that who have been kept there for a very long time.
(19) Panic attacks would overwhelm her periodically and she experienced regular “ scanxiety ” – the feelings of dread that grip patients before new tests.
(20) In the meantime, Malaysia Airlines’ overwhelming focus will be the same as it has been from the outset – to provide the families with a comprehensive support programme.