What's the difference between intercalation and molecule?

Intercalation


Definition:

  • (n.) The insertion of a day, or other portion of time, in a calendar.
  • (n.) The insertion or introduction of anything among others, as the insertion of a phrase, line, or verse in a metrical composition; specif. (Geol.), the intrusion of a bed or layer between other layers.

Example Sentences:

  • (1) It is suggested that the intercalated disc functioned as a barrier to the freezing process.
  • (2) The chiral intercalators, at micromolar concentrations, inhibit the reaction of EcoRI, but for each enantiomeric pair it is the lambda enantiomer, which binds only poorly to a B-DNA helix, that inhibits EcoRI preferentially.
  • (3) The effect of DNA-crosslinking agents (cisplatin and mitomycin C), a DNA-intercalating agent (adriamycin) or monofunctional psoralen (4-Met-4', 5'-dihydropsoralen plus near-ultraviolet radiation) on DNA replication in cultured mouse FM3A cells was studied by sedimentation of the pulse-labeled DNA in an alkaline sucrose gradient.
  • (4) In 1:1 saturated complexes with the octamers [d(GGATATCC)]2 and [d(GGTTAACC)]2, [N-MeCys3,N-MeCys7]TANDEM binds to each octamer as a bis-intercalator bracketing the TpA step.
  • (5) These cells were transformed into intercalated duct cells.
  • (6) We found that the Na-Ca exchanger is distributed throughout all membranes in contact with the extracellular space, including the sarcolemma, the transverse tubules (T-tubules), and the intercalated disks.
  • (7) : the non-specialized parts of the muscle cell membranes were stained by La3+ as well as the membranes of micropinocytotic vesicles, of the T-system and of the intercalated disc.
  • (8) In submandibular glands, 1 to 4 weeks after ovariectomy, no changes were observed in percentages of the acinar, intercalated duct, and granular convoluted tubular areas occupying photomicrographs.
  • (9) Repair not only implies the closing of DNA nicks, but very likely the degradation of the BLM molecules intercalated in the DNA interrupting the reactions responsible for the generation of free radicals.
  • (10) High content of CA II was found in intercalated cells as determined by morphology, although a weak diffuse cytoplasmic staining of this enzyme could be observed also in a subpopulation of principal cells.
  • (11) Laser scanning confocal microscopy has confirmed that the localization of ventricular myocyte gap junctions is solely within intercalated disks.
  • (12) The value of K (4000 M-1) is similar for anti-BADE and 3-MCDE, although the latter is not intercalated in the classical sense since the short axis of the molecule is tilted closer to the axis of the DNA double helix.
  • (13) The complex of 1 is the first example found to date of this type of intercalation of the methyl group with DNA.
  • (14) Transcription proceeded to immediately upstream of CpA sequences in nine of these sites, and this defines the most preferred intercalation site as CpA.
  • (15) Changes in the mode of DNA packaging in nuclei during spermatogenesis were studied by measuring of the fluorescence anisotropy decay of an ethidium dye intercalated in the DNA in whole nuclei.
  • (16) Na-K-ATPase, localized to the basolateral membrane, was more abundant in principal cells than in intercalated cells in the CCD.
  • (17) We have conducted stopped-flow kinetics association and dissociation experiments on the interaction of these anthraquinones with calf thymus DNA and with DNA polymers with alternating AT and GC base pairs to experimentally determine the binding mode and how the threading mode affects intercalation rates relative to similarly substituted classical intercalators.
  • (18) This effect is attributed to intercalation of the ellipticine chromophore.
  • (19) Nerve fasciculi consisting of neuronal processes and enteroglial cell sheaths formed a three-dimensional network intercalated between blood and lymph vessels.
  • (20) A number of unfused tricyclic aromatic intercalators have shown excellent activity as amplifiers of the anticancer activity of the bleomycins and the 4',6-diphenylpyrimidines, 2a and 2b, with terminal basic functions (4-methylpiperazino groups) have been synthesized to test the structural requirements for amplifier-DNA interactions.

Molecule


Definition:

  • (n.) One of the very small invisible particles of which all matter is supposed to consist.
  • (n.) The smallest part of any substance which possesses the characteristic properties and qualities of that substance, and which can exist alone in a free state.
  • (n.) A group of atoms so united and combined by chemical affinity that they form a complete, integrated whole, being the smallest portion of any particular compound that can exist in a free state; as, a molecule of water consists of two atoms of hydrogen and one of oxygen. Cf. Atom.

Example Sentences:

  • (1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
  • (2) Glucocorticoids have numerous effects some of which are permissive; steroids are thus important not only for what they do, but also for what they permit or enable other hormones and signal molecules to do.
  • (3) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
  • (4) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
  • (5) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
  • (6) However, the presence of these two molecules was restored if testosterone was supplemented immediately after orchiectomy.
  • (7) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
  • (8) PMNs could be primed for PMA-triggered oxidative burst by muramyl peptide molecules (MDP) and two of its adjuvant active nonpyrogenic derivatives.
  • (9) These same molecules may be equally responsible for the pathologic characteristics of the immune response seen, for example, in inflammatory bowel diseases.
  • (10) A cDNA library prepared from human placenta has been screened for sequences coding for factor XIIIa, the enzymatically active subunit of the factor XIII complex that stabilizes blood clots through crosslinking of fibrin molecules.
  • (11) T cell costimulation by molecules on the antigen presenting cell (APC) is required for optimal T cell proliferation.
  • (12) The lipid A moiety was shown to be responsible for this novel biological activity of the LPS molecule.
  • (13) Both systems indicated that the Kupffer cell modified endotoxin by enriching the lipid content of the molecule and shortening the length of the O-antigen.
  • (14) Photoreactions induced in that proper sensitizer molecules absorb UV-light or visible light.
  • (15) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
  • (16) Flow cytofluorometric analysis of the strain distribution of the molecules defined by the mAb revealed that two of the antibodies (I-22 and III-5) were directed against nonpolymorphic determinants of Thy-1, whereas V-8 mAb reacted only with Thy-1.2+ lymphocytes.
  • (17) At a fixed concentration of nucleotide the effectiveness of elution was proportional to the charge on the eluting molecule.
  • (18) The relative rates of reduction of several spin-labeled molecules that partition differently across the hy-drophobic-interface of inner membranes from rat liver mitochondria were investigated.
  • (19) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
  • (20) Much information has accumulated on the isolation and characterization of a heterogeneous group of molecules that inhibit one or more of the bioactivities of interleukin 1.

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