What's the difference between interchange and substitute?

Interchange


Definition:

  • (v. t.) To put each in the place of the other; to give and take mutually; to exchange; to reciprocate; as, to interchange places; they interchanged friendly offices and services.
  • (v. t.) To cause to follow alternately; to intermingle; to vary; as, to interchange cares with pleasures.
  • (v. i.) To make an interchange; to alternate.
  • (n.) The act of mutually changing; the act of mutually giving and receiving; exchange; as, the interchange of civilities between two persons.
  • (n.) The mutual exchange of commodities between two persons or countries; barter; commerce.
  • (n.) Alternate succession; alternation; a mingling.

Example Sentences:

  • (1) The results indicated that the higher-M(r) somatostatin-like species isolated from the hypothalamus did not result from hormone polymerization by means of disulfide interchange.
  • (2) In contrast, interchange of the histones and tightly bound non-histone protein DNA complexes from hormone-withdrawn and estrogen-stimulated chromatins during reconstitution did not affect the level of mRNAOV sequences produced.
  • (3) Because SP-A enhances the endocytosis of phospholipids by alveolar type II cells and alveolar macrophages, we examined whether these two molecules were functionally interchangeable.
  • (4) Single and isochromatid breaks including gaps, premature chromosome condensation, irregular staining, stretching of the centromere and interchange, i.e.
  • (5) Data analysis suggests a three-stage model for the kinetics of Alkaline Phosphatase inhibition by urea and related compounds, involving a consecutive binding process with several sites of the protein and the production of different and interchanging inhibitor-enzyme complexes, leading to irreversibly inactivated forms.
  • (6) Protein Mor has a C region sequence associated with Mcg-, Kern-, and Oz- proteins but differs from protein Sut by the presence of three amino acid interchanges at positions 168, 176, and 194.
  • (7) Apoproteins A and B (Apo A and Apo B) were measured using Mancini's method, Glycemia levels (Gly) by peroxidase's method, Glycosilated Serum Protein (GSP) by colormetric's method and Glycosilated haemoglobine (HbA1c) by chromatographic separation using cationic interchange microcolumns.
  • (8) TFIIDs from all three organisms are interchangeable among all three systems.
  • (9) Finally, the two rates interchanged spontaneously over several days without any significant interval changes in medical therapy.
  • (10) The first and third courses were interchanged and consisted of either a sweet (candy bar) or savory (cheese or crackers) food, both of similar palatabilities and energy densities.
  • (11) The variable residue Leu-28 of Escherichia coli dihydrofolate reductase (DHFR) and the corresponding residue Phe-31 in murine DHFR were interchanged, and the impact on catalysis was evaluated by steady-state and pre-steady-state analysis.
  • (12) This situation demands more scientific interchange between officials and scientists from the FDA and their counterparts from Europe.
  • (13) Interchange of media, after 24 h culture, did not enhance the ability of cultured 2-cell embryos to become blastocysts.
  • (14) We conclude that VO2max(ex) and VO2max(cold) cannot be used interchangeably as measures of aerobic capacity.
  • (15) 5-Bromo-2'-deoxyuridine triphosphate (Br-dUTP) and dTTP are used interchangeably for DNA synthesis in vitro by the Klenow fragment of Escherichia coli DNA polymerase I.
  • (16) The finding that the carbon analogue 11 (two methylenes for the disulfide bridge) was devoid of activity is consistent with the hypothesis that histamine H2-receptor inhibition is the result of a covalent bond formation by a way of a disulfide-thiol interchange reaction between the disulfide moiety of tetraamine disulfides and a receptor thiol group.
  • (17) But the term private investigator was used uncorrected in the questions and responses in parliament, suggesting the terms may be interchangeable.
  • (18) In contrast to the situation in XX males, we can exclude paternal X-Y interchange as the etiology in the cases described here.
  • (19) We found that the promoter is extremely G + C rich (72% GC content) and contains a "TAATA" and a "CAT" box, eight "GGGCGG", three "CCGCCC" and two "CACCC" motifs and a motif similar to the glucocorticoid responsive element (GRE) which included two interchanged nucleotides "TCTTGT".
  • (20) Heather Titley said she saw Cameron grab the collar of Noye's shirt and scuffle with him at the Swanley interchange of the M25.

Substitute


Definition:

  • (n.) One who, or that which, is substituted or put in the place of another; one who acts for another; that which stands in lieu of something else
  • (n.) a person who enlists for military service in the place of a conscript or drafted man.
  • (n.) To put in the place of another person or thing; to exchange.

Example Sentences:

  • (1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
  • (2) In the clinical trials in which there was complete substitution of fat-modified ruminant foods for conventional ruminant products the fall in serum cholesterol was approximately 10%.
  • (3) To clarify the functional roles of His40, Glu58, and His92, we analyzed the consequences of several amino acid substitutions (His40Ala, His40Lys, His40Asp, Glu58Ala, Glu58Gln, and His92Gln) on the kinetics of GpC transesterification.
  • (4) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
  • (5) The resonance Raman spectra of oxy and deoxy cobalt-substituted hemoglobin (CoHb) are reported.
  • (6) The most important conclusion of both conferences was that oestrogen substitution can significantly reduce the incidence of fractures in postmenopausal women.
  • (7) S-methyl-l-cysteine, 2-hydroxy-4-methiol butyric acid, S-adenosyl-l-methionine, and methionine peptides were the only compounds supporting growth, when substituted for methionine.
  • (8) This implies that the epitope(s) of NNA-PLA2 might comprise some substituted residues in the sequence of PLA2 homologues.
  • (9) The deletions and substitutions appear to occur in separate molecules.
  • (10) Combination of domain substitutions to generate the [Glu107,123]bFGF and [Arg19,Lys123,126]bFGF mutants did not show any additivity of the mutations on biological activity.
  • (11) N-Methoxysulphonamides showed no inhibitory activity, as predicted by the classic work of Krebs on N-substituted inhibitors.
  • (12) Substitution of NaCl in the extracellular medium by sucrose, LiCl, or Na2SO4 had no effect on glutamate stimulation of [3H]dopamine release; however, release was inhibited when NaCl was replaced by choline chloride or N-methyl-D-glucamine HCl.
  • (13) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
  • (14) Substitutes: Andoni Zubizarreta (Spain), Lajos Detari (Hungary), Dragan Stojkovic (Yugoslavia), Igor Belanov (USSR), Preben Elkjær Larsen (Denmark), Lars Larsson (Sweden), Alexandre Zavarov (USSR).
  • (15) Lipoprotein concentrations reverted to normal after substitution with thyroxine (T4) until the euthyroid state was reached.
  • (16) Taken together with our previous studies showing that MDMA substitutes for the phenylisopropylamine stimulant (+)amphetamine, but that neither MDE nor N-OH MDA substitute for (+)amphetamine or for the phenylisopropylamine hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), the present results [i.e., MDMA-stimulus generalization to MDE, N-OH MDA, but not to (+)amphetamine] suggest that 1) MDMA produces effects other than those that may be considered amphetamine-like, and 2) MDE and N-OH MDA are MDMA-like agents with even less of an amphetamine-like component of action than MDMA itself.
  • (17) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
  • (18) Substitution of DnaK protein with that of the mutant DnaK756 protein blocks lambda P release.
  • (19) To selectively stain polyanionic macromolecules of growth plate cartilage and to prevent artifacts induced by aqueous fixation, proximal tibial growth plates were excised from rats, slam-frozen, and freeze-substituted in 100% methanol containing the cationic dye Alcian blue.
  • (20) Plasma drug concentrations, subjective self-ratings, and the digit symbol substitution test (DSST) were evaluated during 24 hours after dosage.

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