(1) The results presented refute arguments that these enzymes proceed by a concerted mechansim and support the intermediacy of aminoacyladenylates.
(2) This inactivation was very rapid but reversible, with regeneration of enzyme activity being spontaneous and hydrazine-accelerated, suggestive of the intermediacy of a stable acyl enzyme.
(3) A series of different related diethoxy-phosphorous-acid derivatives were also synthesized; their (31P)-NMR signals between 123.9 and 130.8 ppm are additional evidence for the intermediacy of a tetrazolide species.
(4) Using [14C]cholesterol-labeled membranes and HPLC with radiodetection, we identified 3 beta-hydroxy-5 alpha-cholest-6-ene-5-hydroperoxide as the major cholesterol photoproduct, thereby confirming 1O2 intermediacy.
(5) A microsomal preparation from seedlings of Zea mays catalyzed the NADPH dependent reduction of the delta 7-bond of delta 5,7-cholestadienol (1) giving the first in vitro evidence for the intermediacy of delta 5,7-sterols in plant sterol biosynthesis.
(6) A number of other related products generated by reaction of cyclase with the analog were also identified, the structures and proportions of which were consistent with the intermediacy in catalysis of a cyclopropylcarbinyl cation X pyrophosphate anion pair.
(7) 262, 962], implied the intermediacy of a substrate imine complex in the catalytic redox mechanism.
(8) The epimerization of ecdysone to 3-epiecdysone has been investigated in a dialysed cytosolic enzyme preparation from midgut of sixth instar Spodoptera littoralis larvae, with particular emphasis on establishing the intermediacy of 3-dehydroecdysone.
(9) These studies are consistent with 1O2 intermediacy in the mechanism of MC540-mediated photosensitization.
(10) If the biological conversion of cholest-7-en-3beta-ol (I) into cholesterol (IV) occurred thorugh the intermediacy of cholest-7-ene-3beta,5alpha-diol (II) then the factor(s) adversely affecting the convwesion of the 5alpha-hydroxy sterol (II) into cholesterol must at least equally adversely affect the formation of cholesterol from cholest-7-en-3beta-ol.
(11) Kinetics for the base-catalyzed hydrolysis of compounds 9--13 were investigated by UV and NMR methods and are considered in connection with service of these compounds as pro(phosphorodiamidic acid mustards) [MP(O)(NHR)OAr leads to MP(O)(NHR)OH] via an E1cB mechanism involving the intermediacy of a mustard-bearing metaphosphorodiimide [MP(O)=NR].
(12) GTP gamma S alone stimulated both the release of free arachidonic acid and production of diacylglycerol (DAG), while EGF itself neither stimulated DAG nor augmented the DAG response to GTP gamma S. These findings suggest the intermediacy of a G-protein in PLC-independent stimulation of PLA2 by a growth factor, and provide a model system for determining the relationship between G-protein intermediacy and the intrinsic tyrosine kinase activity of the growth factor receptor.
(13) However, O2-, H2O2, and iron are all required for lipid peroxidation and nondisulfide crosslinking, suggesting the intermediacy of OH generated via the iron-catalyzed Haber-Weiss reaction.
(14) This interaction suggests that the site of nucleoside attachment is in close proximity to the 12-methyl group and that binding occurs, therefore, through the intermediacy of a 3,4-diol-1,2-oxide, i.e.
(15) Comparison of the yields of CO2 from this series of compounds suggests the intermediacy of malonic semialdehyde in the metabolism of MDA.
(16) The results tend to indicate that progesterone is as good a precursor of cardenolides as pregnenolone It is suggested that the biosynthesis of cardenolides might proceed through the intermediacy of progesterone.
(17) The formation of the 5-bromo derivatives under the reported conditions probably occurred through the intermediacy of the 3,5-acyloxonium ions.
(18) A mechanism for the removal of the 14alpha-methyl group in ergosterol biosynthesis that involves the intermediacy of an 8,14-diene system is outlined.
(19) The results are compatible with the intermediacy of certain of these arene oxides in the metabolic pathway from hydrocarbons to phenols.
(20) Heterozygotes displayed strict intermediacy for all kinetic and structural properties examined.
Intermediary
Definition:
(a.) Lying, coming, or done, between; intermediate; as, an intermediary project.
(n.) One who, or that which, is intermediate; an interagent; a go-between.
Example Sentences:
(1) A former Berlusconi aide, Valter Lavitola, is also on trial for being the alleged intermediary in the bribe.
(2) About half of the total of the 13 selected parameters showed reactions of the intermediary metabolism of the test groups caused by the feeding.
(3) In his notorious 1835 Minute on Education , Lord Macaulay articulated the classic reason for teaching English, but only to a small minority of Indians: “We must do our best to form a class who may be interpreters between us and the millions whom we govern; a class of persons, Indians in blood and colour, but English in taste, in opinions, in morals and in intellect.” The language was taught to a few to serve as intermediaries between the rulers and the ruled.
(4) Officials in Israel, using intermediaries in Europe, tried to reach out to Ayatollah Khamenei, via Khatami.
(5) McCain, a former Republican presidential candidate with an influential voice on US foreign affairs, is seen by the Obama administration as a potentially important intermediary in its intensive push to persuade Congress to swing behind the plan for airstrikes .
(6) The role of 20,000 local authority housing officers has yet to be rethought and could act as universal credit intermediaries.
(7) These local glomerular constrictor actions of LTD4 support the possibility that this eicosanoid might play an important intermediary role in the functional impairment accompanying some forms of inflammatory injury.
(8) Lateral diffusion from the surrounding choroid into the optic nerve was detected but diffusion from the prelaminar optic nerve into the juxta-optic nerve retina was prevented by the Kuhnt intermediary tissue.
(9) Fillings were made of Concise composite resin, without applying an intermediary resin (1), after applying the resin layer (2), after diluting the mix with one (3) or two (4) drops of catalyst resin but without an intermediary resin, and after diluting the mix and applying the resin layer (5).
(10) In a social policy and decision-making context, the nurse is an intermediary between political authorities and community groups.
(11) Magnesium deficiency is an important but rather neglected intermediary factor for the occurrence of (avoidable) side effects of renal, ototoxic and cardiac nature, emerge when using cytostatics, immunosuppressives and antibiotics.
(12) Pyruvate inhibits Escherichia coli K-12 biodegradative threonine dehydratase activity by a mechanism distinct from product inhibition by alpha-ketobutyrate and catabolite inactivation by intermediary metabolites.
(13) Mediterranean patients (N = 16) had features intermediary between the two other groups.
(14) Soluble fibrin is observed in patients with intravascular coagulation and represents an intermediary product of conversion of fibrin monomers into a fibrin clot whereby the presence of fibrinogen may suppress fibrin clot formation.
(15) A reaction scheme is proposed which postulates that two electrons are transferred from guaiacol to compound I giving ferriperoxidase and oxidized guaiacol with the intermediary formation of compound II.
(16) Rent for the restaurants is paid to a separate UK company, itself also owned by a Netherlands intermediary.
(17) As far as local intermediaries are concerned, these hunters are simply the latest bunch of rich eccentrics, coming to or travelling through Africa either to hunt like the white explorers and colonialists, or go on safaris like honeymooners.
(18) Oman has been an important intermediary in the past between Washington and Tehran, and Alawi met P0resident Hassan Rouhani and aides to Iran’s supreme leader on a visit to the Iranian capital last weekend.
(19) Receptors are linked to membrane-bound, signal-transducing proteins which act as intermediaries in the generation of second messengers that elicit biological responses.
(20) The nature of the changes in the intermediary metabolites suggested that rise in blood glucose was caused by insufficient insulin.