(a.) Not tolerable; not capable of being borne or endured; not proper or right to be allowed; insufferable; insupportable; unbearable; as, intolerable pain; intolerable heat or cold; an intolerable burden.
(a.) Enormous.
Example Sentences:
(1) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
(2) Several pedigrees have been reported in which defects of the insulin gene result in glucose intolerance or diabetes in affected members, but the role of insulin gene mutations in NIDDM is unknown.
(3) Total white cell counts were reviewed in paediatric in-patients with viral gastroenteritis, bacterial gastroenteritis, delayed recovery following acute gastroenteritis, viral lower respiratory tract infections and cow's milk protein intolerance.
(4) Stress may increase to an intolerable level with the number of tasks, with higher qualified work and due to the lack of familiarity with fellow workers in ever changing settings.
(5) In the remaining 39% the most common causes were represented by intolerance reactions (16%), infection causes (16%) and physical causes (13%).
(6) Thirteen asthmatic subjects (six aspirin tolerant and seven aspirin intolerant) in a stable clinical condition and ten healthy subjects were studied.
(7) In some of the 10 patients who tolerated cow's milk challenge clinically there was an increase in both IgA- and IgM-containing cells suggestive of a local immunological reaction although no clinical intolerance was provoked and other immunological signs were weak or absent.
(8) Obesity is characterized by a high risk for glucose intolerance and cardiovascular disease.
(9) To determine the pathogenesis of carbohydrate intolerance associated with gonadal dysgenesis, plasma glucose, insulin, glucagon, and growth hormone responses to oral glucose and intravenous tolbutamide, arginine and insulin were evaluated in 21 nonobese patients, 7-19 years old.
(10) Pregnancy, hyperthyroidism and intolerances are given as contraindications.
(11) Reasons for stopping treatment early included progressive disease, stable disease without symptomatic improvement, or severe toxicity deemed intolerable by either the patient or physician.
(12) An obsessional artist who was an enemy of all institutions, cinematic as well as social, and whose principal theme was intolerance, he invariably gets delivered to us today by institutions - most recently the National Film Theatre, which starts a Dreyer retrospective this month - that can't always be counted on to represent him in all his complexity.
(13) Most patients with abnormal OGTT's fell into the latter group, but some had glucose intolerance without either an exaggerated insulin response or insulin resistance.
(14) Commonly associated medical problems include hypertension in 50%, hyperlipidemia in 41%, and diabetes mellitus or glucose intolerance in 14%.
(15) Eleven infants recovering from protein-calorie malnutrition secondary to acquired monosaccharide intolerance were found to have reduced plasma bicarbonate concentration associated with inadequate weight gain.
(16) These include disease activity, presence or absence of symptoms, degree of deformity and resultant potential for complications, shoe intolerance, and level of activity.
(17) Our ability to design effective countermeasures to orthostatic circulatory intolerance is severely handicapped by our inadequate knowledge of the basic hemodynamic events incident to normal and abnormal orthostatic tolerance.
(18) Cow's milk protein intolerance (CMPI) is recognised as an important cause of protean symptoms in infants.
(19) Successful use of PMP in one steroid and cytotoxic drug intolerant patient with AIED led to its use in a total of eight patients.
(20) Extracardiac adverse effects of quinidine include potentially intolerable gastrointestinal effects and hypersensitivity reactions such as fever, rash, blood dyscrasias and hepatitis.
(a.) Giving pain or unpleasant sensations; disagreeable; revolting; noxious; as, an offensive smell; offensive sounds.
(a.) Making the first attack; assailant; aggressive; hence, used in attacking; -- opposed to defensive; as, an offensive war; offensive weapons.
(n.) The state or posture of one who offends or makes attack; aggressive attitude; the act of the attacking party; -- opposed to defensive.
Example Sentences:
(1) The strike, which Central Command said destroyed the Isis fighting position, follows Barack Obama's vow in his televised speech on Wednesday to go on the offensive against Isis more broadly in Iraq and, soon, Syria.
(2) New offensive coach Tony Sparano was also a fan of Wildcat packages when he was head coach in Miami.
(3) We all do different things.” She was front and centre at Ashley’s side in footage shot last week by Sky News cameramen, who were also part of the “selected media” entourage invited to Shirebrook to launch the group’s charm offensive.
(4) Such extravagant claims will be familiar to the scheme's architect, Richard Rogers, whose designs for the office development beside St Paul's Cathedral in the 1980s were torpedoed when Charles implied in a public speech that the plans were more offensive than the rubble left by the Luftwaffe during the blitz.
(5) The central hypothesis of our study, then, was that psychotic men, charged with misdemeanor offenses, would be incarcerated for significantly longer periods of time, prior to trial, than their nonpsychotic fellows.
(6) It's not that Thompson isn't a a very good player – he and Steph Curry have been running one of the most potent offensives in the NBA over the last two years or so and he's obviously a much better defensive player than Love.
(7) It’s no good me swearing on a Bible; I don’t share your faith.” Morrison said: “I will do it, Ray, but I think it’s a very offensive thing for you to ask me to do but I’ll do it if that’s what you require...if you insist I will.” Hadley did not persist with the demand.
(8) The mean number of different types of drugs "ever used" was 5.87, and the mean number of drug sale offenses was 4.4.
(9) 18) Dallas Cowboys Last season: 8-8 Needs: Offensive line, safety, defensive tackle, running back Pick: Kenny Vaccaro, safety, Texas Tony Romo often carries the can for the Cowboys' offensive calamities, but the truth is that not many quarterbacks look great when they are running for their lives.
(10) 3.46am BST Here's the instant response from Ewen MacAskill , at the scene of the debate-crime: Barack Obama staged a strong comeback in his second showdown with Mitt Romney, with the president describing his Republican opponent as "offensive" in suggesting he was playing politics over Benghazi and portraying him as more extreme than George W Bush on social issues such as women's rights.
(11) Speaking in Washington on Thursday, the Iraqi prime minister, Haider al-Abadi, said the offensive underscored the growing threat posed by Isis militants – whom he referred to using the group’s Arabic acronym “Daesh”.
(12) Kurdish peshmerga forces backed by the US-led coalition have launched attacks on Islamic State east of Mosul as the campaign to oust the militants stepped up with three offensives across Iraq and Syria.
(13) Partners to the drug-treated mice showed a decrease in the occurrence of offensive ambivalence and of the element "rattle".
(14) UN envoy Staffan De Mistura halted the latest Syria talks on 3 February, because of major differences between the two sides, exacerbated by increased aerial bombings and a wide military offensive by Syrian troops and their allies under the cover of Russian airstrikes.
(15) Top Gear presenter Clarkson, who has been repeatedly criticised for making offensive comments, had condemned Sky for the decision, describing it as "heresy by thought".
(16) The unremitting assault on Aleppo by Russian and Syrian forces over recent days is certainly testament to that.” In a week of what residents have described as the worst airstrike campaign since the start of the civil war in Syria , forces loyal to Assad have begun the early stages of a ground offensive aimed at reclaiming eastern Aleppo, which has been under opposition control since 2012.
(17) However, the growing offensive against the left by the pro-capitalist wing of the Labour party inevitably had a damaging impact on the LPYS.
(18) In April 2009, he launched the first concerted offensive against the extremists, routing them in the Swat valley in the north-west, before starting the continuing operations in Pakistan's Taliban-controlled tribal area, which runs along the Afghan border.
(19) The so-called “709 crackdown” has alarmed activists and foreign observers who view the offensive as part of a broader bid to consolidate political control by an increasingly authoritarian leadership.
(20) Since the beginning of December, MNLA leaders have been broadcasting their plans to start an offensive, led by the head of the movement's military wing, Colonel Mohamed Ag Najim.