(a.) Not tolerable; not capable of being borne or endured; not proper or right to be allowed; insufferable; insupportable; unbearable; as, intolerable pain; intolerable heat or cold; an intolerable burden.
(a.) Enormous.
Example Sentences:
(1) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
(2) Several pedigrees have been reported in which defects of the insulin gene result in glucose intolerance or diabetes in affected members, but the role of insulin gene mutations in NIDDM is unknown.
(3) Total white cell counts were reviewed in paediatric in-patients with viral gastroenteritis, bacterial gastroenteritis, delayed recovery following acute gastroenteritis, viral lower respiratory tract infections and cow's milk protein intolerance.
(4) Stress may increase to an intolerable level with the number of tasks, with higher qualified work and due to the lack of familiarity with fellow workers in ever changing settings.
(5) In the remaining 39% the most common causes were represented by intolerance reactions (16%), infection causes (16%) and physical causes (13%).
(6) Thirteen asthmatic subjects (six aspirin tolerant and seven aspirin intolerant) in a stable clinical condition and ten healthy subjects were studied.
(7) In some of the 10 patients who tolerated cow's milk challenge clinically there was an increase in both IgA- and IgM-containing cells suggestive of a local immunological reaction although no clinical intolerance was provoked and other immunological signs were weak or absent.
(8) Obesity is characterized by a high risk for glucose intolerance and cardiovascular disease.
(9) To determine the pathogenesis of carbohydrate intolerance associated with gonadal dysgenesis, plasma glucose, insulin, glucagon, and growth hormone responses to oral glucose and intravenous tolbutamide, arginine and insulin were evaluated in 21 nonobese patients, 7-19 years old.
(10) Pregnancy, hyperthyroidism and intolerances are given as contraindications.
(11) Reasons for stopping treatment early included progressive disease, stable disease without symptomatic improvement, or severe toxicity deemed intolerable by either the patient or physician.
(12) An obsessional artist who was an enemy of all institutions, cinematic as well as social, and whose principal theme was intolerance, he invariably gets delivered to us today by institutions - most recently the National Film Theatre, which starts a Dreyer retrospective this month - that can't always be counted on to represent him in all his complexity.
(13) Most patients with abnormal OGTT's fell into the latter group, but some had glucose intolerance without either an exaggerated insulin response or insulin resistance.
(14) Commonly associated medical problems include hypertension in 50%, hyperlipidemia in 41%, and diabetes mellitus or glucose intolerance in 14%.
(15) Eleven infants recovering from protein-calorie malnutrition secondary to acquired monosaccharide intolerance were found to have reduced plasma bicarbonate concentration associated with inadequate weight gain.
(16) These include disease activity, presence or absence of symptoms, degree of deformity and resultant potential for complications, shoe intolerance, and level of activity.
(17) Our ability to design effective countermeasures to orthostatic circulatory intolerance is severely handicapped by our inadequate knowledge of the basic hemodynamic events incident to normal and abnormal orthostatic tolerance.
(18) Cow's milk protein intolerance (CMPI) is recognised as an important cause of protean symptoms in infants.
(19) Successful use of PMP in one steroid and cytotoxic drug intolerant patient with AIED led to its use in a total of eight patients.
(20) Extracardiac adverse effects of quinidine include potentially intolerable gastrointestinal effects and hypersensitivity reactions such as fever, rash, blood dyscrasias and hepatitis.
Untolerable
Definition:
(a.) Intolerable.
Example Sentences:
(1) During 30 days of evaluation, the aneurysm grew larger and his cervical pain became untolerable.
(2) 3 patients suffered untolerable headache during isosorbide dinitrate phase and had to terminate treatment after first day only.
(3) They were operated on radically, except one case whose status seemed to be untolerable to the operation.
(4) A 36-year-old female was referred as aortitis c AR with atypical coarctation of aorta (obstruction of both subclavian arteries and long stenosis of lt. common carotid artery) and complained of untolerable angina repeatedly in the state of NYHA IV.
(5) The untolerant mice were never detectably chimeric.
(6) The induced damages of the prostate and surrounding tissue is not severe enough to be untolerable.
(7) The result of pain relief is classified into 4 grades based on Hitchcock's criteria; grade 1: complete pain relief, grade 2: almost complete pain relief with slight residual pain, grade 3: persisting pain, but tolerable, grade 4: persisting pain, untolerable.
(8) To prevent withdrawal from the therapy as a result of untolerable adverse effects, the daily dose was set at 1 X 10(6) units, and rIL2 was given to 12 patients with metastatic renal cell carcinoma.
(9) Conservative septoplastic techniques through Cottle's approach produce an untolerably high rate of recurrence or insufficient restoration of the function of the nose.
(10) Final ALS of untolerated animals contained antibodies against 7 to 8 fractions, whereas that of experimental group tolerated with serum and Hb was free of antibodies against serum protein, hemoglobin included.