(n.) Want of capacity to endure; as, intolerance of light.
(n.) The quality of being intolerant; refusal to allow to others the enjoyment of their opinions, chosen modes of worship, and the like; want of patience and forbearance; illiberality; bigotry; as, intolerance shown toward a religious sect.
Example Sentences:
(1) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
(2) Several pedigrees have been reported in which defects of the insulin gene result in glucose intolerance or diabetes in affected members, but the role of insulin gene mutations in NIDDM is unknown.
(3) Total white cell counts were reviewed in paediatric in-patients with viral gastroenteritis, bacterial gastroenteritis, delayed recovery following acute gastroenteritis, viral lower respiratory tract infections and cow's milk protein intolerance.
(4) Stress may increase to an intolerable level with the number of tasks, with higher qualified work and due to the lack of familiarity with fellow workers in ever changing settings.
(5) In the remaining 39% the most common causes were represented by intolerance reactions (16%), infection causes (16%) and physical causes (13%).
(6) Thirteen asthmatic subjects (six aspirin tolerant and seven aspirin intolerant) in a stable clinical condition and ten healthy subjects were studied.
(7) In some of the 10 patients who tolerated cow's milk challenge clinically there was an increase in both IgA- and IgM-containing cells suggestive of a local immunological reaction although no clinical intolerance was provoked and other immunological signs were weak or absent.
(8) Obesity is characterized by a high risk for glucose intolerance and cardiovascular disease.
(9) To determine the pathogenesis of carbohydrate intolerance associated with gonadal dysgenesis, plasma glucose, insulin, glucagon, and growth hormone responses to oral glucose and intravenous tolbutamide, arginine and insulin were evaluated in 21 nonobese patients, 7-19 years old.
(10) Pregnancy, hyperthyroidism and intolerances are given as contraindications.
(11) Reasons for stopping treatment early included progressive disease, stable disease without symptomatic improvement, or severe toxicity deemed intolerable by either the patient or physician.
(12) An obsessional artist who was an enemy of all institutions, cinematic as well as social, and whose principal theme was intolerance, he invariably gets delivered to us today by institutions - most recently the National Film Theatre, which starts a Dreyer retrospective this month - that can't always be counted on to represent him in all his complexity.
(13) Most patients with abnormal OGTT's fell into the latter group, but some had glucose intolerance without either an exaggerated insulin response or insulin resistance.
(14) Commonly associated medical problems include hypertension in 50%, hyperlipidemia in 41%, and diabetes mellitus or glucose intolerance in 14%.
(15) Eleven infants recovering from protein-calorie malnutrition secondary to acquired monosaccharide intolerance were found to have reduced plasma bicarbonate concentration associated with inadequate weight gain.
(16) These include disease activity, presence or absence of symptoms, degree of deformity and resultant potential for complications, shoe intolerance, and level of activity.
(17) Our ability to design effective countermeasures to orthostatic circulatory intolerance is severely handicapped by our inadequate knowledge of the basic hemodynamic events incident to normal and abnormal orthostatic tolerance.
(18) Cow's milk protein intolerance (CMPI) is recognised as an important cause of protean symptoms in infants.
(19) Successful use of PMP in one steroid and cytotoxic drug intolerant patient with AIED led to its use in a total of eight patients.
(20) Extracardiac adverse effects of quinidine include potentially intolerable gastrointestinal effects and hypersensitivity reactions such as fever, rash, blood dyscrasias and hepatitis.
Tolerance
Definition:
(n.) The power or capacity of enduring; the act of enduring; endurance.
(n.) The endurance of the presence or actions of objectionable persons, or of the expression of offensive opinions; toleration.
(n.) The power possessed or acquired by some persons of bearing doses of medicine which in ordinary cases would prove injurious or fatal.
Example Sentences:
(1) within 12 h of birth followed by similar injections every day for 10 consecutive days and then every second day for a further 8 weeks, with mycoplasma broth medium (tolerogen), to induce immune tolerance.
(2) No differences between the two substances were observed with respect to side effects and general tolerability.
(3) This treatment is usually well tolerated but not devoid of systemic effects.
(4) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(5) To estimate the age of onset of these differences, and to assess their relationship to abdominal and gluteal adipocyte size, we measured adiposity, adipocyte size, and glucose and insulin concentrations during a glucose tolerance test in lean (less than 20% body fat), prepubertal children from each race.
(6) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(7) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(8) There were no biochemical or haematological abnormalities caused by prazosin but on continued therapy 16 patients developed tolerance to its effect.
(9) Characerization of further parameters such as relative susceptibility to tolerance induction and relative degree of specificity was not possible with the use of KLH as the antigen.
(10) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
(11) Efficacy and tolerability of perorally administered desmopressin were evaluated in 12 adult patients suffering from central diabetes insipidus.
(12) This suggests that both blood transfusion and allograft are required for IL2 suppression and that this suppression may be related to the heart tolerance.
(13) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(14) Changes in pain tolerance after administration of differently labelled placebos were studied by measuring the reaction time after a cold stimulus.
(15) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(16) Provided that adequate reflection is given and the appropriate moment chosen, it is well tolerated and provides all the necessary information.
(17) After large bowel removal, there was impaired glucose tolerance and attenuated plasma insulin secretion.
(18) Cardiac pump function is not affected, even in patients with ventricular dysfunction or heart failure, in whom chronic oral administration of the drug is well tolerated.
(19) These agents have been well-tolerated and generally produce a high incidence of sustained improvements in neutrophil counts and marrow morphology, although hemoglobin and platelet counts have generally not been altered.
(20) The above treatment is tolerated well and no serious side effects have been observed.