(v. t.) To render invalid; to weaken or lessen the force of; to destroy the authority of; to render of no force or effect; to overthrow; as, to invalidate an agreement or argument.
Example Sentences:
(1) Especially in the old patients (over 70 years) the incisional hernias represents an invalidating pathology whose treatment, for the high incidence of associated diseases of respiratory and cardiocirculatory apparatus in the aged, offers difficulties connected both to surgical methods and to the perioperative evaluation and preparation of patients.
(2) Thus neither the presence of changes in RS-T segment or T wave nor the absence of QRS changes are mandatory for the diagnosis of SEMI; this invalidates the common assumption that the diagnosis is not justified unless these conditions are met.
(3) It was found that good results had 53.2% of the patients, 12.8% of the patients had limited working capacity, 4.6% of the patients became invalids.
(4) Awareness of problems that may arise in the physician-patient relationship may prevent such outcomes as suicide, anxiety, hypochondriasis, invalidism and psychotic symptoms.
(5) It imposes a standard of logical reductionism and methodological purity that not only violates the nature of psychoanalytic knowledge, but imposes an invalid standard of verification and scientific confirmation.
(6) In this event it may be possible to prevent invalidating effects on fertility and chronic pelvic pain.
(7) Lutzomyia may be defined geographically, but the use of geographical distribution in taxonomy leads to circular biogeographical arguments, and is invalid.
(8) 36% of the group had abstained from further drug taking, 27% were taking them periodically, 32% had to be treated again and 5% had deteriorated (trend towards invalidism).
(9) Jim Devine, Labour MP for Livingston, was reportedly under investigation for invoices he submitted for electrical work worth more than £2,000 from a company with an allegedly fake address and an invalid VAT number.
(10) Sources of invalidity may relate to subject factors or to circumstances under which data are collected.
(11) The postulated interference of therapeutic levels of alpha-methyldopa on the phosphotungstate uric acid method was invalid.
(12) These recent findings invalidate our previous conclusion that isozyme 3a is not induced by ethanol treatment of rabbits.
(13) Respecting the frequency of invalidity this cancer pretends the second place among these diseases.
(14) Any criminal cases which rested on acquisition of data through the directive could also be called into question, because the court decided that "the declaration of invalidity takes effect from the date on which the directive entered into force" – that is, 2006.
(15) It is emphasized that various effects of anaesthetics unrelated to their anaesthetic properties may obscure or even invalidate results obtained with drugs acting on the peripheral sympathetic nervous system.
(16) In clinical trials, information and consent problems usually relate to the possibility that information given the participant will invalidate the findings.
(17) But the appeals court decided that while the warrants were defective in some respects it was not enough to declare them invalid.
(18) She emphasizes the mortality life expectancy at birth, abortion rate, work incapacity on account of illness and injury, morbidity from diabetes and tuberculosis, the trend of newly detected malignant tumours and causes of invalidity.
(19) Trainmen and railroad clerks were used as reference cohorts.The engineers had relatively high invalidity and mortality rates in comparison to the reference groups, especially with respect to cardiovascular diseases and malignant tumors.
(20) Results were invalidated if calculations were based on initial slope of the wash-out curves.Topical application of beta-methasone valerate in a reduction in cutaneous blood flow as measured by the intracutaneous technique with curve resolution, whereas no effect could be demonstrated when calculations were based on the initial slopes of the curves.
Vitiate
Definition:
(v. t.) To make vicious, faulty, or imperfect; to render defective; to injure the substance or qualities of; to impair; to contaminate; to spoil; as, exaggeration vitiates a style of writing; sewer gas vitiates the air.
(v. t.) To cause to fail of effect, either wholly or in part; to make void; to destroy, as the validity or binding force of an instrument or transaction; to annul; as, any undue influence exerted on a jury vitiates their verdict; fraud vitiates a contract.
Example Sentences:
(1) These conclusions vitiate previous explanations for gal3 associated long-term adaptation and noninducible phenotypes.
(2) Thus it is concluded that any solution or drug which needs to be injected should ideally be used at 37 degrees C, as temperature lower or higher than that may vitiate the results.
(3) Their review is marred by numerous errors which vitiate the potency estimates.
(4) Antibiotic therapy prior to hospitalization did not vitiate the validity of the test.
(5) The following is concluded: (1) diagnosis of folate and B12 deficiency based on SF, RCF and serum B12 is vitiated in HBT and needs a therapeutic trial; (2) iron overload of a magnitude indicated by TS greater than 50% can aggravate anemia in HBT.
(6) The technique is simple but the results may be vitiated by the minutae of preservation, of taking or of staining the cells which are described.
(7) Some of the previous results (Ascenzi et al., 1985) indicating a high hemoglobin titer were +vitiated because of an unexpected cross-reactivity of bone extracts with the hemoglobin-unreactive fraction of the antiserum.
(8) The authors have classified the various fractures of the pelvis in children by analysing the elements of functional prognosis of these lesions based on the types of fractures and on the particular factors of vitiation reported in the literature, consisting of series which are too short to be truly demonstrative.
(9) While the physiological role of these proteins remains to be determined, their presence in gonadal extracts or fluids vitiates assessment of FSH within the gonad by RIA using antiserum against hFSH.
(10) It was also found that the protective effect is vitiated by the concurrent administration of paraaminobenzoic acid.These studies indicate a need for further assessment of the antimalarial value of sulfones and sulfonamides, both alone and in combination with other drugs, for prevention and cure.
(11) In particular, the extent to which the generality of the model is vitiated by its ignoring the effect of mineralisation on strength was tested.
(12) These conclusions are not vitiated by differences in the number of nuclei within capillaries or in satellite cells, by differences in nuclear length or by variation in the degree to which fibres are contracted.
(13) Infection or ileal conduit urine vitiate the result as they produce high CEA levels in the urine in the absence of any neoplastic disease.
(14) It is argued that despite continued methodological improvements, subjects in the conditions of greater complexity may have found it sufficient to rotate only partial images, thereby vitiating the prediction.
(15) The failed bid by prime minister Antonis Samaras to throw off the yoke of international supervision by prematurely exiting the bailout programme has also vitiated his fragile government’s appeal.
(16) An investigation of the risky shift phenomenon revealed that an understanding of probability did not vitiate the shift toward greater risk.
(17) The several factors which do not depend directly on the orifice area or on the forward stroke volume vitiate the sole use of the orifice formula in the analysis of the dynamics of aortic stenosis.
(18) Mutations not detectable by analysis with the method of Southern with pDP1007, may occur in the testicular determinant factor gene vitiating testicular development.
(19) It is believed that a.m. are an important drawback contributing to vitiate any formula on the amount of muscle surgery to be performed in patients having no possibilities of restoring normal binocular vision.
(20) The stimulatory effect was vitiated by cycloheximide indicating the involvement of intermediate genes in the PLP gene activation.