(n.) An invariable quantity; specifically, a function of the coefficients of one or more forms, which remains unaltered, when these undergo suitable linear transformations.
Example Sentences:
(1) In X-irradiated litters, almost invariably, the incidence of anophthalmia was higher in exencephalic than in nonexencephalic embryos and the ratio of these incidences (relative risk) decreased toward 1 with increasing dose.
(2) On the other hand, the injection of minute quantities of endotoxin into PbAc(2)-sensitized rats invariably resulted in disseminated intravascular coagulation, apparently via a complete activation of the intrinsic pathway.
(3) The cytoplasmic and membrane spanning domains of galactosyltransferase were found to be sufficient to retain all of the hybrid invariant chain in trans Golgi cisternae as judged by indirect immunofluorescence, treatment with brefeldin A and immuno-electron microscopy.
(4) The purification and concentration of these viruses in their monomeric forms is hazardous when conventional "tube" rotors are used since they invariably result in dissociation and aggregation of the virus particles.
(5) In contrast, cases of parkinsonism beginning before age 21 years were invariably familial.
(6) Examination of the two types of tissue fragments revealed that IS-treated ICMs almost invariably retained viable endoderm cells whereas MS-isolated ectoderms did so only exceptionally.
(7) It is suggested that a general manner of folding may be a common feature of the heterogeneous population of kappa-chains: one bridge which folds an invariable stretch of the chain, another bridge which folds a stretch that varies from protein to protein, and a bridge at the C-terminus which is the interchain link.
(8) An obsessional artist who was an enemy of all institutions, cinematic as well as social, and whose principal theme was intolerance, he invariably gets delivered to us today by institutions - most recently the National Film Theatre, which starts a Dreyer retrospective this month - that can't always be counted on to represent him in all his complexity.
(9) Patients with anti-NC1 antibodies were characterised by linear immune deposits along the glomerular basement membrane and the clinical outcome was invariably grim.
(10) The PCR amplified a 375-bp DNA fragment which was cloned and sequenced; the deduced amino acid sequence had significant identity with known TS sequences, including strict conservation of all phylogenetically invariant TS amino acid residues.
(11) Using confirmatory factor analysis on an independent sample (N = 377), these dimensions were tested for factorial invariance across spouse and nonspouse caregivers and between caregivers of persons with cancer and those caring for persons with Alzheimer's disease.
(12) The species invariance of this lysine residue, number 175, and the substantial conservation of adjacent sequence support the probability for a functional role in catalysis of the lysyl epsilon-amino group.
(13) Under these assumptions, any time-invariant variable may behave like a metabolite concentration, i.e.
(14) However, in conical cells the new oral apparatus and fission line form well posterior to the cell equator, so the opisthes are invariably smaller than proters.
(15) Unlike posterior tympanoplasty, this technique makes it possible to meticulously remove the osteitic bone invariably found in the facial recess when there is infection of the retraction pocket.
(16) Limited data indicates that, while enhanced thermal stability invariably results, the optimum temperature for catalysis may not change.
(17) The relative invariance of the allometric baselines of wing morphology in nature is most easily explained as the result of continuous natural selection around a local optimum of functional design.
(18) When the paper had some explaining to do, Kuttner was invariably asked to carry out that task.
(19) We found that NS1 cells express correctly sized mRNA for the MHC class II genes A alpha, E alpha and the invariant chain.
(20) When we reached our summit, or whatever spot was deemed by my father to be of adequately punishing distance from the car to deserve lunch, Dad would invariably find he had forgotten his Swiss army knife (looking back, I begin to doubt he ever had one) and instead would cut cheese into slices with the edge of his credit card.
Variegate
Definition:
(v. t.) To diversify in external appearance; to mark with different colors; to dapple; to streak; as, to variegate a floor with marble of different colors.
Example Sentences:
(1) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
(2) Such characteristics are reminiscent of the behavior of variegating position-effects in Drosophila and the application of this paradigm to human disease phenotypes provides both a mechanism by which differential genome imprinting may be accomplished as well as genetic models that may explain the clinical association of syntenic diseases, the association between tumor progression and specific chromosomal aneuploidy and the unusual inheritance characteristics of many diseases.
(3) The diagnosis depends on fecal excretion of porphyrins, which is greatly increased in variegate porphyria and consists predominantly of protoporphyrin.
(4) Although clinical improvements occurred in the case of variegate porphyria, the results were inconclusive for reasons given.
(5) Appropriate laboratory tests on urine and feces samples are necessary to distinguish between PCTS and variegate porphyria when a young woman presents with the skin lesions characteristic of cutaneous hepatic porphyrias.
(6) One patient with variegate prophyria and two with hereditary coproporphyria had an attack related to pregnancy.
(7) The theory of the unconscious that arises from the method of direct interpretation reflects a differentiated inner world with variegated landscapes of images and frameworks.
(8) The faecal porphyrin patterns of 24 patients with porphyria cutanea tarda symptomatica (PCTS), eight patients with variegate porphyria, three patients with other types of porphyria, and 20 non-porphyrics subjects have been compared using a two-demensional thin layer chromatographic technique that separates porphyrins of the isocoproporphyrin series from other faecal porphyrins.
(9) A 62-year-old man with variegate porphyria is reported.
(10) Four patients with variegate porphyria (VP) were treated with repeated haem arginate infusions daily for 4 days and then weekly for 4 weeks.
(11) Hence, the differences in binding of the w+ gene probe in the variegating and variegation-suppressed strains reflect differences in chromosomal packaging rather than alterations in gene number.
(12) The lesions appeared brownish black, and most were variegated from tan to black.
(13) Thus, mice with variegating transgenes can provide molecular access to gene control mechanisms and to their consequences in development and disease.
(14) The results provide some indication as to the mechanism and timing for the general suppression of position-effect variegation by supernumerary heterochromatin in the genome.
(15) Beautiful and ancient plants, such as spreading bellflower , could become extinct in some places through the escape of variegated yellow archangel from gardens.
(16) Variegated endocrine cells were documented within this lining, using immunohistochemical and ultrastructural techniques.
(18) In white-mottled (wm) position-effect variegation mutants, a significant correlation was found between the extent of variegation (percentage of yellow cells) and riboflavin content (growth effect) of the MT.
(19) Four patients suffering from variegate prophyria were investigated during acute attacks.
(20) These changes include variegated hyperplasia of the pulp with epithelioid cells, mature eosinophilic granulocytes and immunoblasts occasionally resembling Hodgkin cells.