(n.) A curve traced by the end of a string wound upon another curve, or unwound from it; -- called also evolvent. See Evolute.
Example Sentences:
(1) Here we report direct measurements of protein kinase C (PKC) activity in uninduced ectoderm, and in neuroectoderm shortly after induction by the involuting mesoderm, in Xenopus laevis embryos.
(2) The most common type of osteoporosis is involutional, and two subtypes are recognized: type 1 and type 2.
(3) The involution of crown odontoblasts after primary dentinogenesis in teeth of limited eruption is discussed.
(4) The treatment of hemangiomas with X-rays has been sharply criticized because of their tendency to involute spontaneously.
(5) Glands with only slight involution and containing numerous germinal centres were more commonly seen in young female patients.
(6) In conclusion, the association of T4 and iodide seems to be the best way to obtain a rapid and complete involution of thyroid hyperplasia.
(7) Less amount of parenchyma and growth of the stroma in baboons and a greater mitotic complex in rhesus monkeys show more pronounced involution processes in baboons.
(8) Further, CPA is unable to stimulate proliferation or restore the function of the involuted rat prostate.
(9) The MI response was however depressed in both age groups, and the thymus and bursa were involuted.
(10) It is concluded that the acute involution of the thymus in children with non-infectious and acute infectious diseases results in the progressive decrease of the production by the thymus of the immunomodulating polypeptides (thymic hormones) which is restored in the period of recovery.
(11) The involution progress of the tonsil is a shift from immature B- and T cell forms to matured differentiation stages.
(12) The interpretation of aspiration cytologic smears that contain a predominance of follicular components often presents a dilemma to the clinician who is treating a patient who has a dominant thyroid nodule, especially when thyroid-stimulating hormone suppression does not produce any significant involution of the dominant nodule.
(13) The time-courses of the biochemical and histopathological responses suggest that the lipid peroxidation may be an end-result, rather than a cause, of thymic involution and injury to thymic lymphocytes in nickel-treated rats.
(14) We conjecture that postmenopausal and involutional osteoporosis were far advanced before the development of acromegaly, explaining the coexistence of the two conditions.
(15) The myoepithelium of developing, lactating, and involuting mammary gland of the mouse exhibits a high alkaline phosphatase activity.
(16) Both the post-partum involution of the rat uterus and the rapid breakdown of collagen that accompanies it are extensively inhibited by oestrogenic hormones.
(17) These preparations revealed a failure of head involution and the loss or disruption of several head structures, including the salivary glands and the H-piece and ventral arm of the cephalopharyngeal apparatus.
(18) Thereafter, involution still continued and equal diameters for the horns were not found until 5 weeks after parturition.
(19) The enzymes glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, phosphoglucomutase, UDP-glucose pyrophosphorylase, phosphofructokinase, ATP-citrate lyase and acetyl-CoA carboxylase have been assayed in rat mammary glands in various stages of involution after hypophysectomy and weaning.
(20) A total of 101 patients suffering from slowly progressive schizophrenia with hypochondriac symptomatology and a manifestation or a relapse of the disease in the involutional age have been studied.
Unwind
Definition:
(v. t.) To wind off; to loose or separate, as what or convolved; to untwist; to untwine; as, to unwind thread; to unwind a ball of yarn.
(v. t.) To disentangle.
(v. i.) To be or become unwound; to be capable of being unwound or untwisted.
Example Sentences:
(1) Unlike cisplatin, bis(platinum) complex binding does not unwind supercoiled DNA.
(2) Of the 47 compounds that were positive or equivocal in the alkaline unwinding assay, only carbon tetrachloride and prednisolone were negative in the mouse lymphoma assay, while 12 of the 19 compounds that were negative in the alkaline unwinding assay were positive in the mouse lymphoma assay.
(3) As suggested from the high level of sequence similarity of these viral proteins with the recently described superfamilies of helicase-like proteins (3-5), the NTBM-containing cylindrical inclusion (CI) protein from plum pox virus (PPV), which belongs to the potyvirus group of positive strand RNA viruses, is shown to be able to unwind RNA duplexes.
(4) This limited unwinding of heterologous duplex DNA, termed heterologous unwinding, was detected within 30 seconds and reached a steady state within a few minutes.
(5) Comparison of the superhelix densities obtained by both methods permits a calculation of an unwinding angle for ethidium.
(6) The exposure of the cells from mussel haemolymph and from mouse L1210 to a genotoxic compound such as dimethylsulfate results in DNA damage and consequently in a reduction of the unwinding time.
(7) As for unwinding, the rituals of it give a satisfying end to the shape of my day.
(8) Chromosome replication appears to initiate in E. coli when the dnaA boxes in oriC become filled with DnaA protein, which could simultaneously mediate both the unwinding of the origin for the start of polymerization and the attachment of oriC to the cell envelope (Bramhill and Kornberg, 1988; Løbner-Olesen et al., 1989; Pierucci et al., 1989).
(9) The protein fraction containing the 93 000 dalton protein had considerable unwinding activity, depressing the melting temperature of poly(dA-dT) by 39 degrees C. The protein fraction containing the bulk of the 35 000 dalton protein did not have unwinding activity.
(10) The required cellular protein may be a eukaryotic single-stranded-DNA-binding protein (SSB), since unwinding of the template is also observed when Escherichia coli SSB is substituted for the HeLa protein fraction.
(11) Evidence is presented that the first step in initiation of SV40 DNA replication involves the specific binding of T antigen to the origin, followed by the local unwinding of the two strands of the template.
(12) Complex formation leads to very little, if any, unwinding of the duplex.
(13) It is suggested that the gene D product may function in replicative form DNA unwinding to expose the template for transcription.
(14) Topotecan (SK&F 104864) is a novel antitumor agent whose mechanism of action is inhibition of the DNA unwinding protein topoisomerase I.
(15) We used an RNA unwinding assay to compare the activities of these factors from the different species.
(16) The extension and unwinding of the DNA helix brought about by the intercalating chromophore of the dye molecules are not requirements for the entrapment process.
(17) Second, mutant T antigens with impaired ATPase function also showed a reduced DNA unwinding activity.
(18) Analysts at UBS said: “After Friday’s ... market plunge, many turned to the authorities for support measures as concerns rose that the rapid unwinding of margin trades was fuelling the sell-off.
(19) It is proposed that the DNA-unwinding activity causes the efficient recombination, DNA repair, and SOS induction (after application of nalidixic acid) in recD mutants.
(20) But within minutes of the five-year-old video of Obama being released by the Daily Caller website on Tuesday night , the "exclusive" began to unwind amid criticism that much of it had been reported at the time and the content was anything but explosive.