(1) An insulin response element (IRE) has been identified in the prolactin gene using chimeric plasmids in which prolactin promoter DNA directs expression of the bacterial chloramphenicol acetyltransferase gene.
(2) The lability of the Fe-S cluster in mitochondrial aconitase has led us to propose that the mechanism by which iron levels are sensed by the IRE-BP involves changes in an Fe-S cluster in the IRE-BP.
(3) Government officials drew the public’s ire after charging Manning with three counts of misconduct following the suicide attempt, including two which carried possible penalties of indefinite solitary confinement.
(4) In a prospective, blinded trial, 40 healthy adult subjects using six IRED thermometers with two techniques were examined in random sequence.
(5) On Wednesday, the ire of the marchers was focused on all those Lib Dems who blithely signed the NUS's anti-fees pledge ("I pledge to vote against any increase in fees in the next parliament and to pressure the government to introduce a fairer alternative" – yesterday, Nick Clegg limply said that he "should have been more careful" than to put his name to it).
(6) Oleg Sentsov should make new films, not count years in prison.” Facebook Twitter Pinterest Oleg Sentsov sings the Ukrainian national anthem as he is sentenced to 20 years in a Russian penal colony Sentsov attracted the ire of the Russian authorities after helping to organise a campaign protesting at Russia’s occupation and annexation of Crimea in March 2014.
(7) A deletion and reconstitution study was undertaken to address the possibility that regions of the ferritin gene and mRNA other than the IRE may be necessary for the production of the full range of iron regulation.
(8) Her predecessor, Nick Robinson, attracted similar ire by upsetting Scottish nationalists .
(9) Interestingly, the FRP which remains active at a given hemin concentration binds to the IRE with the same high affinity as untreated FRP.
(10) The results strongly suggest that HCV RNA carries an internal ribosome entry site (IRES).
(11) Among the 17 pancreatic cancer patients with elevated IRE, 10 underwent radical resection of the cancer but in none of the five patients with normal serum IRE could radical resection be carried out.
(12) In addition, a poor sequence context around AUG-11 results in increased initiation at one or more downstream AUG codons, indicative of leaky scanning or jumping by the ribosome from AUG-11 mediated by the EMCV IRES.
(13) Amino acid alignments reveal that the IRE-BP is 30% identical to mitochondrial aconitase.
(14) Regulation in both instances is mediated by binding of a cytosolic protein to the IREs.
(15) Binding of the IRE-BP represses ferritin translation and represses degradation of the TfR mRNA.
(16) Yet in doing so it presents an angled mirror-polished cliff face of glass, which has been reflecting the sun straight across into the Lloyds offices across the road – the seminal "inside-out" machine that Rogers designed 30 years earlier – much to the ire of its tenants.
(17) The nations with the highest recorded levels include Colombia, Uganda, Afghanistan, India, Pakistan, Bangladesh and Nepal, with the south Asian countries in particular producing unforgettable images of disfigured women who have been assaulted with acid because they have rejected sexual advances or marriage proposals, or aroused jealousy, or in some way or other inconvenienced the patriarchy and aroused its ire.
(18) Artificial mono- and dicistronic mRNAs were prepared and used to identify the region that carried the IRES.
(19) Two melanotic human melanoma cell lines, IRE 1 and IRE 2, and the lymphoma- and leukaemia-derived cell lines Raji and K 562, were exposed to different concentrations (from 5 X 10(-3) M to 10(-5) M) of phenols, both substrates (s) and non-substrates (ns) of tyrosinase, in the presence or absence of the oxygen-radical-scavenger enzymes superoxide dismutase, catalase and peroxidase.
(20) Afterwards, she was "suddenly beautiful", and though the attention this brought was occasionally useful, mostly it was just a pain in the butt: the tiresome suggestions that she had only got on thanks to her appearance; the hurtful ire of that other great feminist, Betty Friedan, whose loathing of Steinem seemed mostly to be motivated by envy.
Wroth
Definition:
(a.) Full of wrath; angry; incensed; much exasperated; wrathful.
Example Sentences:
(1) The King's friendship with Robert Carr (who was later made Earl of Somerset), coupled with his estrangement from Queen Anne, may have been an inspiration for at least two literary accounts of kingship confounded by sex: Lady Mary Wroth's Urania (1621) and Shakespeare's Antony and Cleopatra (1608).
(2) The rise and fall of this disloyal companion closely resembles that of Somerset and would seem to indicate Wroth's belief that the King's relationship with the Earl was sexual.
(3) Wroth describes a duke who is made politically vulnerable by his love for a young man that leaves him "issue-les."