(v. t.) To weary; to give pain; to annoy; -- used only impersonally at present.
Example Sentences:
(1) When the rats were grouped into animals with mild (20%), moderate (50%), and severe (80%) reductions in maximal IRK activity, it was found that the mild and moderate defects could be reversed once the receptors were subjected to extensive autophosphorylation in vitro.
(2) We characterized the mechanism of IRK inhibition and studied whether it is the consequence of a glucose-induced stimulation of protein kinase C (PKC).
(3) 18 May 2014 New £69.4bn proposal, worth £55 a share, piles pressure on AstraZeneca's board to enter negotiations with Pfizer 19 May 2014 AstraZeneca board rejects Pfizer's final £69bn takeover bid , irking some large shareholders
(4) Reports of George’s stag do at Ristorante da Ivo near St Mark’s Square with the free £3,000 meal featuring six flavours of ice cream, including takeaway cartons, initially irked me.
(5) Joleon Lescott last weekend irked supporters by clumsily saying relegation was a “weight off the shoulders”.
(6) Wenger must be the only manager in football to be irked by reports that he will be offered a new deal.
(7) Walking by last Monday, Trump gestured towards an image of his inauguration crowd – a point that still irks him – and told reporters there would soon be an official statement about the future of his national security adviser, Michael Flynn.
(8) Blogger Yomi Adegoke said: "Thinly veiling vanity as philanthropy more than irks … the pretence these images are for anything other than an onslaught of 'natural beauty' acclamations, coupled with pats on the back for 'fighting the cause' makes the no makeup selfie mania even harder to stomach."
(9) We, therefore, conclude that glucose intolerance in aging could be attributed at least in part to acquired defects in the in vivo activation of the hepatic IRK, which results in reduced phosphorylation of its putative substrate pp180.
(10) But while agreeing that the results should not be exaggerated, D'Alimonte still thinks they indicate that the Five Star shine is wearing off among some voters - including those who were irked by the rambunctious figurehead's refusal to support a minority government led by the centre-left Democratic party (PD), thus forcing the PD to form a coalition with Berlusconi's centre-right.
(11) The corporation's power online and expanding digital TV and radio channels have irked beleaguered commercial rivals, resulting in an attack by James Murdoch, head of News Corporation in the UK.
(12) The home crowd turned their ire on the Hungarian referee Viktor Kassai – his decision to dismiss Piiroja for handball in the 76th minute particularly irked them – but they were deluding themselves if they thought he was to blame.
(13) Right now is not the time.” The midfielder refused to be drawn on suggestions that his team-mates were irked by his comments, and insisted the atmosphere among the squad in Brazil was similar to during the glorious Euro 2012 campaign.
(14) Hyperglycemia causes insulin-receptor kinase (IRK) resistance in fat cells.
(15) The comments irked the geologists' professional body, which was founded in 1807 as a dining club in a London pub.
(16) Philip Hammond appears to have irked the prime minister by making a sexist remark in cabinet, exposing the tensions at the highest level of government.
(17) Look, he’s the clear frontrunner, he’s been in six debates already, answered more questions from the media than any other candidate on the stage combined.” The Fox News press release that irked Trump and led to his withdrawal read: “We learned from a secret back channel that the Ayatollah and Putin both intend to treat Donald Trump unfairly when they meet with him if he becomes president – a nefarious source tells us that Trump has his own secret plan to replace the Cabinet with his Twitter followers to see if he should even go to those meetings.” Trump derided it as “a wise guy press release .
(18) To determine whether defects in insulin receptor kinase (IRK) activity or in the phosphorylation of its physiological substrates underlie this age-related phenomenon, young (2-3 months old) and old (24-27 months old) Wistar rats were studied.
(19) Field has already irked the medallion stallion with some low blows before the bell has rung, but it looks doubtful whether punches will be pulled for the number crunchers.
(20) Linehan, who turned 44 last week, is irked by the persistence of the idea that the sitcom that brought him and Arthur Mathews to the attention of millions has canned laughter on it.
Kirk
Definition:
(n.) A church or the church, in the various senses of the word; esp., the Church of Scotland as distinguished from other reformed churches, or from the Roman Catholic Church.
Example Sentences:
(1) By the time Van Kirk returned to the US in June 1943, he had flown 58 combat and eight transport missions.
(2) Hemsworth cut his chops on Home And Away before quitting in 2007, moving to LA and almost immediately being cast as Kirk's doomed dad in JJ Abrams 's Star Trek.
(3) Animal Practice is a Universal Television production based on an irreverent New York veterinarian, played by Justin Kirk of Weeds and Angels in America.
(4) It dismays Kirk that Warp moved to London but he's still in touch with them and their releases, effusing particularly about DJ Mujava and "Township Funk".
(5) By focusing on Spock and Kirk as novices finding their footing, and putting their gut-vs-logic dynamic at the heart of the film, Abrams gives non-followers plenty to hang on to, but also pays homage to familiar Trek tropes: Bones says: "I'm a doctor, not a physicist!
(6) Ins(1,3,4)P3 was dephosphorylated to two InsP2 (inositol bisphosphate) isomers, one of which is Ins(3,4)P2 [Shears, Parry, Tang, Irvine, Michell & Kirk (1987) Biochem.
(7) The IPCC report acknowledged "significant" work done in response to the failings in the Worboys case and that of another undetected serial rapist, Kirk Reid.
(8) The letter was organised by Oregan Democrat Ron Wyden, a member of the intelligence committee, but includes four Republican senators: Mark Kirk, Mike Lee, Lisa Murkowski and Dean Heller.
(9) It charts the successful career of the manipulative and promiscuous radical sociologist, Howard Kirk, at the new University of Watermouth (which bears more than a passing resemblance to East Anglia), and satirises savagely his substitution of "trends for morals and commitments".
(10) Chris Kirk is a consultant and former civil servant who worked for the international profit-making education company Gems and is now with an academy chain, but has never been a head.
(11) Graham, A. F. (The Wistar Institute of Anatomy and Biology, Philadelphia, Pa.), and Clare Kirk.
(12) Kirk Douglas wrote to me about his stroke in a spidery, half-legible hand.
(13) His describes his dream as a Star Trek scenario where a Captain Kirk of global financial systems sat at a dashboard with the ultimate spread of data at their fingertips.
(14) Ironic that an experimental music veteran with 20 years behind him should be leading a fresh charge into the 90s, setting up the framework for Autechre, Aphex Twin and the whole intelligent dance music (IDM) scene, but the rise of sampling, rave and techno was the realisation of a music that codgers like Kirk had only been able to dream of decades earlier, prior to the arrival of the technology.
(15) The mid- to late-term rat placenta produces several moderately abundant proteins in a specific temporal manner, one of which we have identified as rat placental lactogen II (rPLII) (Duckworth, M. L., Kirk, K. L., and Friesen, H. G. (1986) J. Biol.
(16) JJ Abrams' Star Trek Into Darkness opens this week and it's a big, loud science fiction movie, cobbled together from the scripts of two Kirk-era movies, with action scenes rehashed from Abrams' last Trek outing.
(17) It is time to stop calling each other names, time to shun the idea that we should define ourselves by our differences and instead define ourselves by what we hold in common – our baptism into Christ, our dependence on God’s grace, our will to serve the poor and so on.” Co-ordinator of the principal clerk’s office, Very Rev David Arnott, said: “The General Assembly of the Church of Scotland decided today to allow individual kirk sessions the possibility of allowing a nominating committee to consider an application from a minister living in a civil partnership.
(18) In a live Q&A, ESPN's Kirk Herbstreit asked Eminem what he was "most excited about with this new album".
(19) Speaking after Sunday service outside Crathie Kirk near her Balmoral estate in Aberdeenshire, the Queen told a wellwisher: “ Well, I hope people will think very carefully about the future.
(20) Staying as a guest of the chancellor, Gordon Brown, in his Scottish constituency, Mr Greenspan delivered the 14th Adam Smith lecture at St Bryce Kirk in Kirkcaldy, where Mr Brown's father was the minister.