(a.) Not reparable; not capable of being repaired, recovered, regained, or remedied; irretrievable; irremediable; as, an irreparable breach; an irreparable loss.
Example Sentences:
(1) The reasons for enucleation were a choroidal melanoma in two patients and endophthalmitis and irreparable traumatic damage in one patient each.
(2) At operation irreparable fibrotic changes were observed in four patients, but in 15 a pattern of proximal focal obstruction with relatively healthy distal internal carotid vessels was observed.
(3) The fascia lata sling procedure has been used over the past 22 years in our unit for treating recurrent urinary stress incontinence when irreparably poor local support tissues were suspected.
(4) More extensive genetic tests made subsequently (de Serres, 1989a) on the 832 X-ray-induced specific-locus mutations recovered in those experiments showed that unexpected high frequencies of reparable and irreparable ad-3 mutants are actually multiple-locus mutants that have additional, but separate, sites of recessive lethal (RLCL) damage in the immediately adjacent genetic regions (designated ad-3R + RLCL or ad-3IR + RLCL).
(5) Removal of irreparably blocked testes in 10 men led to profound falls in high antisperm antibody titres, with production of two pregnancies.
(6) A playwright and actor has launched legal action against British Airways and London City airport, alleging that they irreparably damaged her £25,000 wheelchair, made her daily life more difficult and caused problems for her business.
(7) The caffeine-induced increase in the number of irreparable DNA damages, attributed to inhibition of double-strand break repair, is in a quantitative correlation with the effect of the cytogenetic damage modification.
(8) A time lag between the release of cytoplasmic enzymes and lysosomal enzymes and other observations made in the present study suggests a sequential order of events in which the release of cytoplasmic enzymes occurs at a stage of reversible damage due to oxygen deprivation, whereas the release of lysosomal enzymes may point at irreparable damage.
(9) "They fear these reforms could cause irreparable and irreversible damage to the NHS."
(10) Newville’s original suit, filed in June, argues that the ban subjects same-sex couples seeking to marry to “an irreparable denial of their constitutional rights” and the state “will incur little to no burden in allowing same-sex couples to marry and in recognizing the lawful marriages of same-sex couples from other jurisdictions on the same terms as different-sex couples”.
(11) Based on the results available in literature, significance of an early detection of female genital tract inflammations caused by Chlamydia trachomatis because of its often asymptomatic flow, irreparable sequels of uncured inflammation and possible curing with tetracyclines and macrolides therapy has been discussed.
(12) These data do not support the routine use of a constrained prosthesis for irreparable rotator cuff tears.
(13) It is clear that the Iraq war did irreparable damage to public confidence in intelligence assessments and policymaking, to the point where it constrained future decision-makers and dealt an enduring moral blow to the global standing of western foreign policies.
(14) Neither BA nor the airport have admitted liability for the parts they and their agents are alleged to have played in what Stevens says is irreparable damage to the chair, which is no longer made.
(15) Business lobby groups anxious to protect the country's lucrative exports of machine tools, cars and chemicals have claimed Germany would suffer "irreparable damage", losing its dominant economic position to China if sanctions escalate.
(16) Irreparable renal damages developed at temperatures between 0 and -3 degrees C.
(17) These irreparable lesions include double-strand scissions and some form(s) of single-strand breaks.
(18) The political impasses and economic shocks in our societies, and the irreparably damaged environment, corroborate the bleakest views of 19th-century critics who condemned modern capitalism as a heartless machinery for economic growth, or the enrichment of the few, which works against such fundamentally human aspirations as stability, community and a better future.
(19) From cell survival curves obtained under euoxic and hypoxic conditions, the RBE for the production of irreparable lethal and potentially lethal damage was derived.
(20) To achieve a ban, Apple's case before the judge must pass a four-part test: it must show "irreparable injury" from the devices' previous sale; that monetary damages are inadequate as compensation; that another remedy is warranted; and that a ban on sale is not against the public interest.
Irrevocable
Definition:
(a.) Incapable of being recalled or revoked; unchangeable; irreversible; unalterable; as, an irrevocable promise or decree; irrevocable fate.
Example Sentences:
(1) Continuing corporate concerns over the costs of health care, and recent changes in federal policies regarding Medicare and the taxation of employee benefit funds, threaten to alter the system of postretirement health benefits substantially and perhaps irrevocably for many.
(2) It took the first intifada (the largely unarmed, six-year uprising that preceded the current, far more violent one) to transform Yassin wholly and irrevocably, and to pitchfork him into the forefront of the Palestinian struggle as a serious rival to Arafat himself.
(3) The council had been politically unstable and divided, and although parents were voting with their feet – less than half were choosing to send their children to the borough's secondary schools – there was a widespread feeling that nothing could be done, that the borough's failings were irrevocable.
(4) Tsipras also emphasised that Greece is a “sovereign country with an irrevocable right to conduct a multi-faceted foreign policy”.
(5) Monocytic differentiation was reversible upon removal of CSF-1, implying that CSF-1 was required for maintenance of the monocyte phenotype but was not sufficient to induce an irrevocable commitment to differentiation.
(6) Fertility in women 40 years of age or older is decreased, and in those with ovarian failure it is thought to be irrevocably lost.
(7) Still, there's an upside to 007's monogamy, and it may just explain how this much-maligned film has wheedled its way so irrevocably into my affections: uniquely in the world of Bond, it allows a vein of romantic adventure to develop that's real, not illusory.
(8) The reason for King's change of view is simple: he believes the world changed irrevocably on 15 September last year when the collapse of Lehman Brothers set off a month of financial turmoil that plunged the global economy into a deep slump.
(9) In the first experiment, 14-day prenatal lung explants (14 + 0 days) containing macrophage precursors but not matured cells were exposed to individual CSFs for 7 days in an attempt to determine whether precursors are committed irrevocably to the macrophage line or can be altered by exposure to factors promoting significant granulocyte development.
(10) The team’s failure led to the immediate and “irrevocable” resignations of both the manager and the president of the Italian federation, Giancarlo Abete.
(11) Above all, he must face the increasing suggestion that his party is irrevocably on course to do significantly worse with him as its leader in the 2015 general election than it would do under someone new, specifically the business secretary Vince Cable .
(12) Lord Mandelson, the former Labour business secretary, has also said he is no longer a supporter and that Labour should "think twice before binding themselves irrevocably" to the project Patrick McLoughlin, the transport secretary, rejected Darling's claim that going ahead with HS2 could have "catastrophic" consequences for spending on other transport infrastructure.
(13) In a sworn affidavit accompanying the motion, Dershowitz states that Roberts’s lawyers “levelled totally false and outrageous charges against me that have been damaged around the world and threaten to damage my reputation irrevocably”.
(14) Without the presence and participation of those Jews, Europe irrevocably lost a crucial and invaluable element of its identity.
(15) "We, the people of the Azawad [desert region] proclaim the irrevocable independence of the state of the Azawad starting from this day, Friday 6 April 2012," the statement read.
(16) The irrevocable breakdown of leucine was estimated from the 3H-labelling of body water.
(17) Particularly grave in its consequences is the gastric stump carcinoma with its fateful and irrevocable course for patients with B II gastrectomy if regular gastroscopic and laboratory follow-up inspection do not take place (regardless of questionable operation indication).
(18) Do your own due diligence before making irrevocable choices.
(19) Michael Jacobs, senior adviser for the New Climate Economy project, says the long-term goals in the agreement send investors the clearest sign “that the world was on an irreversible and irrevocable downward trend in emissions”.
(20) But there are deep nerves in Whitehall that George Osborne is reaching the stage where voters will make an irrevocable judgment that he has failed to deliver his two key economic pledges made during the 2010 election.