(a.) Incapable of being reversed or turned about or back; incapable of being made to run backward; as, an irreversible engine.
(a.) Incapable of being reversed, recalled, repealed, or annulled; as, an irreversible sentence or decree.
Example Sentences:
(1) The specific limited trypsinolysis of bacteriophage T7 RNA polymerase (T7RP) was performed in the presence of various components of the polymerase reaction and some GTP-analogs--irreversible inhibitors of the enzyme.
(2) At 24 or 48 hours after ischemia, 63Ni, 99TcO4, and 22Na were preferentially concentrated in the damaged striatum and hippocampus, whereas 65Zn, 59Fe, 32PO4, and 147Pm did not accumulate in irreversibly injured tissue.
(3) The illumination of the F1-ATPase complexes with NAB-ADP or NAB-GDP leads to the covalent binding of one nucleotide analogue molecule to the enzyme and to the irreversible inactivation of F1-ATPase.
(4) The inhibition was irreversible, as well as time and concentration dependent, which indicates a suicide-inhibition type of metabolism.
(5) It is unclear if the changes in high-energy phosphates during endotoxin shock cause irreversibility.
(6) These studies indicate that, in three models of acute liver injury, the net influx of calcium across the plasma membrane is increased early in the evolution of the injury before irreversible damage occurs.
(7) The kinetics of association of the radioligand suggested the presence of a rapidly associating, reversible binding site, and a slowly associating, apparently irreversible one.
(8) The high capacity of irreversible synthetic-state, smooth muscle cells to bind and accumulate beta-VLDL in contrast to the relative immunity of contractile cells may be relevant to the genesis of atherosclerosis in the rabbit and possibly also in humans.
(9) In the MVD, all esters appeared to irreversibly block the agonist effect of morphine, but none of the compounds irreversibly antagonized [D-Ala2,D-Leu5]enkephalin to a significant degree.
(10) The coronary vasoconstrictor response produced by ibopamine was inhibited completely by the irreversible alpha-adrenoceptor antagonist, phenoxybenzamine, whereas the response produced by epinine was transformed into relaxation which was inhibited by the beta-adrenoceptor antagonist, propranolol.
(11) It is concluded that vasectomy should no longer be considered an irreversible procedure.
(12) No correlation occurred between specific immunopatterns and irreversible brochopulmonary lesions.
(13) In patients under anti-epileptic therapy it is readily possible for the clinical picture to be concealed, and this may then result in irreversible damage due to the disturbance of metabolism remaining uninfluenced.
(14) When tissue metabolism was irreversibly inhibited by exposure to formaldehyde, hydrogen ion concentration and pCO2 were significantly decreased in the mucosal side of the chamber compared with the viable gall bladder.
(15) More than 20 years ago Olney and his colleagues described the 'Excitotoxic Hypothesis' which postulates that, in addition to its normal function in the healthy brain, glutamate can kill neurons by prolonged, receptor-mediated depolarization resulting in irreversible disturbances in ion homeostasis.
(16) Hypercalcaemia is a common disorder, which frequently requires specific treatment either to control symptoms, or to prevent the development of irreversible organ damage or death.
(17) The kinetics of inactivation of the Mg(2+)-containing enzyme in 8 M-urea at higher temperatures suggest a partially unfolded Mg-A-B* dimer intermediate with 50% activity, followed by irreversible inactivation coincident with the appearance of unfolded monomer.
(18) The rate of the irreversible damage to the reaction center II, caused by exposure of spinach thylakoids to high light was slowed down by anaerobic conditions and by lowering the temperature.
(19) Rheumatoid arthritis, a disease of unknown aetiology, has a multifactorial pathogenesis which may result in irreversible connective tissue destruction and loss of joint function.
(20) Although neither patient exhibited a toxic effect, these levels may be associated with an increased risk of thioridazine-induced irreversible pigmentary retinopathy, cardiac arrhythmias, and tardive dyskinesia.
Repeal
Definition:
(v. t.) To recall; to summon again, as persons.
(v. t.) To recall, as a deed, will, law, or statute; to revoke; to rescind or abrogate by authority, as by act of the legislature; as, to repeal a law.
(v. t.) To suppress; to repel.
(n.) Recall, as from exile.
(n.) Revocation; abrogation; as, the repeal of a statute; the repeal of a law or a usage.
Example Sentences:
(1) As of July 1987, 10 states have prohibitory laws, five states have grandmother clauses authorizing practicing midwives under repealed statutes, five states have enabling laws which are not used, and 10 states explicitly permit lay midwives to practice.
(2) However, when public disquiet at the crime and social damage caused by alcohol prohibition led to its repeal, Anslinger saw his position as being in danger.
(3) And make no mistake, this is a repeal and a replace of Obamacare.
(4) Facebook Twitter Pinterest Lamar Alexander voted yes but has previously expressed concerns about the rush to repeal without a replacement plan.
(5) If you’re a congressional Republican, you consider Obamacare a “failure”, and “repeal and replace” is your mantra.
(6) In May, Maryland became the sixth state in six years to repeal the death penalty; it is the 18th state in total.
(7) Climate change funding should not be disguised as foreign aid funding,” she said, accusing the former government of introducing the now-repealed carbon tax to pay for contributions to the fund.
(8) He has also demanded the carbon tax repeal be made retrospective.
(9) This possibility makes the repeal of the section particularly urgent and the supreme court's suggestion that it needs to be debated in parliament is nothing more than, well, stonewalling.
(10) The opposition said the government’s approach towards the budget debate in this critical parliamentary sitting week was to stack separate proposals into single bills to avoid scrutiny, particularly in the welfare omnibus bills, and to crowd out the agenda with renewed parliamentary debates on carbon- and mining-tax repeals.
(11) Gravett and others who lived through DADT told the Guardian that so much had changed since the repeal, though the past feels unbelievable at times.
(12) Approved: Nebraska voters passed an unusual ballot measure to reinstate the death penalty after state lawmakers repealed it in 2015.
(13) They opposed the first iteration of the House healthcare bill as not going far enough to repeal Obamacare.
(14) But in the short-term it’s better to have something reducing emissions than having nothing.” Palmer, whose senators also voted to repeal the former government’s emissions trading scheme – which is how Australia was left without a climate policy – said he believed Australia would eventually have to move to such a scheme.
(15) The policy wouldn’t officially be repealed until 20 September 2011.
(16) The demonstrators want a national vote on whether or not to repeal the 8th amendment to Ireland’s constitution, which effectively makes the fetus even at early gestation an Irish citizen.
(17) However, in July the coalition government said it had no plans to repeal the act.
(18) Facebook Twitter Pinterest Many progressives consider the self-described farm girl their worst nightmare: a Tea Party radical who wants to privatise social security, curb abortion rights, repeal Obamacare and abolish the Environmental Protection Agency.
(19) Ironically, the law being used to pursue the groups is one from the era of Mubarak, which the government had said it intended to repeal.
(20) The House speaker, Paul Ryan, said that after Congress’s forthcoming weeklong recess, “we intend to introduce legislation to repeal and replace Obamacare”, without giving further details.