(n.) The state or quality of being irritable; quick excitability; petulance; fretfulness; as, irritability of temper.
(n.) A natural susceptibility, characteristic of all living organisms, tissues, and cells, to the influence of certain stimuli, response being manifested in a variety of ways, -- as that quality in plants by which they exhibit motion under suitable stimulation; esp., the property which living muscle processes, of responding either to a direct stimulus of its substance, or to the stimulating influence of its nerve fibers, the response being indicated by a change of form, or contraction; contractility.
(n.) A condition of morbid excitability of an organ or part of the body; undue susceptibility to the influence of stimuli. See Irritation, n., 3.
Example Sentences:
(1) Postpartum management is directed toward decreasing vasospasm and central nervous system irritability and maintaining fluid and electrolyte balance.
(2) testosterone, fentanyl, nicotine) may ultimately be administered in this way, important questions pertaining to pharmacology (tolerance), toxicity (irritation, sensitisation) and dose sufficiency (penetration enhancement) remain.
(3) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
(4) Inhibition of binding of [3H]TPA to the receptor preparation by tigliane and ingenane DTE correlates with irritant activity in vivo, while some daphnane and 1 alpha-alkyldaphnane DTE inhibit binding of [3H]TPA in a less pronounced manner but still are very irritant.
(5) Exposure to irritants was also more common among the asthmatics than the nonasthmatics with similar exposure to organic allergens (P = 0.004).
(6) The purpose of this study was to develop a new model for the induction of chronic irritant contact dermatitis, which would reflect well the conditions of daily practice.
(7) The drug I started taking caused an irritating, chronic cough, which disappeared when I switched to an inexpensive diuretic.
(8) These injections led to epidermal hyperplasia in areas overlying the irritant and the effect was most significant when the irritant was placed in the upper dermis.
(9) Two children required lidocaine therapy for cardiac irritability manifesting as multifocal PVCs and ventricular tachycardia.
(10) In autumn, leaf-heaps composted themselves on sunken patios, and were shovelled up by irritated owners of basement flats.
(11) The dietary fibre intake of 25 patients with the irritable bowel syndrome was assessed by dietary recall over one week for the period before onset of symptoms, at diagnosis and after six months treatment with bran and a fibre-rich diet, and compared with controls matched for age and sex.
(12) A case of epidermoid tumor of the sacral area with S3 root irritation resulting in bladder dysfunction is presented and its possible relationship to spinal puncture is discussed.
(13) The present study did not identify any baseline parameters such as initial prostate volume, peak flow rates, or obstructive or irritative symptom scores that correlated with clinical outcome.
(14) Scores on the "dependent smoking" subscale of the smoking motivation questionnaire correlated significantly with overall withdrawal severity, craving, and increased irritability.
(15) The airways can be affected by inflammation, can be targets of infection, and can respond to chemical irritants with bronchoconstrictive responses.
(16) Some pulp irritation can occur if deep restorations are not placed over a protective film.
(17) MIDAZOLAM IS SUPERIOR TO DIAZEPAM IN CERTAIN WAYS: it has a more rapid onset; produces greater anterograde amnesia, less postoperative drowsiness, less venous irritation and less likelihood of thrombophlebitis development.
(18) Primary invasive adenocarcinoma of the bladder was diagnosed in a fifty-two-year-old male with a two-month history of irritative voiding symptoms.
(19) We studied seventy patients, 23 males and 47 females with irritable bowel syndrome in adolescence aged 13-19 yrs, who visited the department of psychosomatic medicine in Takano Hospital during about six year period of April, 1986-July, 1992.
(20) The study suggested that 1) diabetes and "prediabetes" produce significant changes in levels of chondroitin 4, 6, and dermatan sulfates within alveolar bone, 2) in "prediabetic" animals, interdental bone loss occurs prior to the onset of clinical symptoms and in the absence of local irritating factors, the bone height appears to return to normal levels, and 3) there may be a correlation between alveolar bone height and relative levels of dermatan sulfate.
Sensitivity
Definition:
(n.) The quality or state of being sensitive; -- used chiefly in science and the arts; as, the sensitivity of iodized silver.
Example Sentences:
(1) Our results suggest that the peripheral sensitivity to hypoxia declined more than that to CO2, implying a peripheral chemoreceptor origin for hypoxic ventilatory decline.
(2) "Zayani reportedly cited the political sensitivity of naturalising Sunni expatriates and wanted to avoid provoking the opposition," the embassy said.
(3) The outward currents are sensitive to TEA and their reversal potentials differ.
(4) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(5) At the early phase of the sensitization a T-cell response was seen in vitro, characterized by an increased spleen but no peripheral blood lymphocyte reactivity to T-cell mitogens at the same time as increased reactivity to the sensitizing antigen was detected.
(6) The presence of O-glycosidic linkages between carbohydrate and protein in the DF3 antigenic site was further supported by the presence of NaBH4-sensitive sites.
(7) This induction is sensitive to actinomycin D but not to protein synthesis inhibitor puromycin, indicating an effect of estradiol at the transcriptional level, possibly mediated by the estrogen receptor.
(8) A total of 13 ascertainments of folate sensitive autosomal fragile sites is observed, of which 10q23 fragility appears to be the most frequent.
(9) Rapid overgrowth of all cultures with the E. coli necessitated the use of selective media containing antimicrobial agents to which the E. coli was sensitive.
(10) The fluctuations in [Ca2+]i measured with fura-2 were synchronized among the population of cells observed and were sensitive to extracellular Ca2+ concentration ([Ca2+]o).
(11) Thus adrenaline, via pre- and post-junctional adrenoceptors, may contribute to enhanced vascular smooth muscle contraction, which most likely is sensitized by the elevated intracellular calcium concentration.
(12) Enhanced sensitivity to ITDs should translate to better-defined azimuthal receptive fields, and therefore may be a step toward achieving an optimal representation of azimuth within the auditory pathway.
(13) A significant correlation was found between the amplitude ratio of the R2 and the sensitivity ratio of the rapid off-response at short and long wavelengths.
(14) When compared with self-reported exposures, the sensitivity of both job-exposure matrices was low (on average, below 0.51), while the specificity was generally high (on average, above 0.90).
(15) The dog and the pig also have an endoperoxide-sensitive constrictor system activated by the 11,9-(epoxymethano) analogue of PGH2 and, of particular note, ICI 79939 and its 11-oxo analogue.
(16) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(17) This Mr 20,000 inhibitory activity was acid and heat stable and sensitive to dithiothreitol and trypsin.
(18) Beta-galactosidase, beta-n-acetyl-hexosaminidase, and alpha-fucosidase were sensitive indicators and were significantly elevated above control values by day 3 at both doses (P < 0.01).
(19) The sensitivity of an indirect fluorescent antibody (IFA) test (screening test) for the detection of antibodies to cytomegalovirus (CMV) was examined by using 128 serum specimens and quaternary aminoethyl (QAE)-Sephadex A50 column chromatography to separate IgM from IgG class antibodies.
(20) The third route was quantitated by its sensitivity to probenecid and its activity was increased in saline buffers and upon addition of glucose and was inhibited by oligomycin.