(n.) The act of isolating, or the state of being isolated; insulation; separation; loneliness.
Example Sentences:
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) On the other hand, human IL-9, which is a homologue to murine P40, was cloned from a cDNA library prepared with mRNA isolated from PHA-induced T-cell line (C5MJ2).
(3) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(4) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(5) One thing seems to be noteworthy in their opinion: the bacterial resistance of the germs isolated from the urine is bigger than the one of the germs isolated from the respiratory apparatus.
(6) Thus, saponin and ammonium chloride can be used to isolate whole infected erythrocytes, depleted of hemoglobin, by selective disruption of uninfected cells.
(7) Detergent-solubilized HLA antigens were isolated from a human lymphoblastoid cell using an anti-beta2-microglobulin immunoaffinity column.
(8) A phytochemical investigation of an ethanolic extract of the whole plant of Echites hirsuta (Apocynaceae) resulted in the isolation and identification of the flavonoids naringenin, aromadendrin (dihydrokaempferol), and kaempferol; the coumarin fraxetin; the triterpene ursolic acid; and the sterol glycoside sitosteryl glucoside.
(9) The present findings indicate that the deafferented [or isolated] hypothalamus remains neuronally isolated from the environment if the operation is carried out later than the end of the first week of life.
(10) Proliferation assays using F3 showed that 15 (14 CD4+ and 1 CD8+) of the 18 isolated clones were specific for T. gondii.
(11) Similar to intact crayfish, animals with an isolated protocerebrum-eyestalk complex, exhibit competent circadian rhythms in the electroretinogram (ERG).
(12) Reiteration VII (within protein coding regions of genes US10 and US11) and reiteration IV (within introns of genes US1 and US12) were stable between the isolates (group 1).
(13) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
(14) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(15) Completeness of isolation of the coronary and systemic circulations was shown by the marked difference in appearance times between the reflex hypotensive responses from catecholamine injections into the isolated coronary circulation and the direct hypertensive response from a similar injection when the circulations were connected as well as by the marked difference between the pressure pulses recorded simultaneously on both sides of the aortic balloon separating the two circulations.4.
(16) At the same time the duodenum can be isolated from the stomach and maintained under constant stimulus by a continual infusion at regulated pressure, volume and temperature into the distal cannula.
(17) Only the approximately 2.7 kb mRNA species was visualized in Northern blots of total cellular and poly(A+) RNA isolated from cardiac ventricular muscle.
(18) These major departmental transformations are being run in isolation from each other.
(19) This postulate is supported by a limited study of the serovars present among the isolates.
(20) Plasma membranes were isolated from rat kidney and their transport properties for sodium, calcium, protons, phosphate, glucose, lactate, and phenylalanine were investigated.
Loneliness
Definition:
(n.) The condition of being lonely; solitude; seclusion.
(n.) The state of being unfrequented by human beings; as, the loneliness of a road.
(n.) Love of retirement; disposition to solitude.
(n.) A feeling of depression resulting from being alone.
Example Sentences:
(1) He's Billy no-mates with a Heckler & Koch sniper-rifle, drowning in loneliness, booze and depression.
(2) I used it primarily as a social lubricant but also to alleviate boredom, stress and loneliness.
(3) Symptom prevalence was associated with anxiety, negative relations with parents, modest plans for education, fear of the future, loneliness, smoking, and drinking.
(4) a person who experienced loneliness did usually not feel completely healthy.
(5) Other factors such as gender, marital status and the presence of children, relatives and friends in the neighbourhood had no association with loneliness.
(6) A median split on the UCLA Loneliness Scale divided subjects into high- and low-scoring loneliness groups.
(7) The epidemic of loneliness and isolation that is spreading through the older population is not confined to people waiting at home for the next visit from a homecare worker, but can be just as acute for the older person waiting in their care home room for the weekly visit from relatives, or even just from a staff member, as was distressingly illustrated by another Panorama exposé this week.
(8) The group differences and the varying patterns of correlations support the use of a multidimensional approach to the study of loneliness.
(9) The purpose of this study was to analyze differences in future time perspective, loneliness and perceived maternal expressiveness between adolescents who were chronically ill with cystic fibrosis and adolescents who were reportedly healthy.
(10) Loneliness and sociocultural isolation appeared to accelerate the rate at which the average "traveler" moved from nonaddictive use to addiction.
(11) Both groups completed two self-concept questionnaires, a loneliness scale, and a measure of their social relationships outside of school.
(12) Suggestions were made for future research on loneliness in school settings.
(13) Such schemes can help people of any age to develop self-acceptance, making it easier for them to relate to others and connect on such a level that loneliness, if not eradicated, at least becomes less of a threat to health.
(14) Loneliness (alpha = .885), higher for males than for females, was significantly correlated with various aspects of their high-school lives.
(15) To non-artists, there may not seem to be anything original or provocative about love, death, loneliness or cheese, either – yet gosh-darned artists keep finding new ways for humanity to look at them.
(16) Using hierarchical analysis of sets, the results indicated that the set of variables used to test the situational theory explained more variance in loneliness when entered first (62%) or second (34%) in the analysis than did the characterological set when entered first (33%) or second (5%) in the analysis.
(17) 'He was like me - desperate for ways to overcome his loneliness.'
(18) Social factors that can greatly reduce an elderly person's interest in food include loneliness, depression, isolation, and self-consciousness because of hearing and visual impairments.
(19) The charity network Acevo, which set up The Loneliness Project last year to tackle social isolation among young people in London, today publishes a report which suggests young Londoners are twice as likely to be lonely as their counterparts elsewhere in the country.
(20) In the thrall of social media and smartphones, we are drip-fed a steady supply of Instagram-filtered intimacy – and in this world, negative emotions and loneliness are taboo.