(n.) The act of isolating, or the state of being isolated; insulation; separation; loneliness.
Example Sentences:
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) On the other hand, human IL-9, which is a homologue to murine P40, was cloned from a cDNA library prepared with mRNA isolated from PHA-induced T-cell line (C5MJ2).
(3) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(4) The ability of azelastine to influence antigen-induced contractile responses (Schultz-Dale phenomenon) in isolated tracheal segments of the guinea-pig was investigated and compared with selected antiallergic drugs and inhibitors of arachidonic acid metabolism.
(5) One thing seems to be noteworthy in their opinion: the bacterial resistance of the germs isolated from the urine is bigger than the one of the germs isolated from the respiratory apparatus.
(6) Thus, saponin and ammonium chloride can be used to isolate whole infected erythrocytes, depleted of hemoglobin, by selective disruption of uninfected cells.
(7) Detergent-solubilized HLA antigens were isolated from a human lymphoblastoid cell using an anti-beta2-microglobulin immunoaffinity column.
(8) A phytochemical investigation of an ethanolic extract of the whole plant of Echites hirsuta (Apocynaceae) resulted in the isolation and identification of the flavonoids naringenin, aromadendrin (dihydrokaempferol), and kaempferol; the coumarin fraxetin; the triterpene ursolic acid; and the sterol glycoside sitosteryl glucoside.
(9) The present findings indicate that the deafferented [or isolated] hypothalamus remains neuronally isolated from the environment if the operation is carried out later than the end of the first week of life.
(10) Proliferation assays using F3 showed that 15 (14 CD4+ and 1 CD8+) of the 18 isolated clones were specific for T. gondii.
(11) Similar to intact crayfish, animals with an isolated protocerebrum-eyestalk complex, exhibit competent circadian rhythms in the electroretinogram (ERG).
(12) Reiteration VII (within protein coding regions of genes US10 and US11) and reiteration IV (within introns of genes US1 and US12) were stable between the isolates (group 1).
(13) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
(14) The agent present in the serum which causes dissolution of the fibrin clot was isolated and identified as pepsinogen.
(15) Completeness of isolation of the coronary and systemic circulations was shown by the marked difference in appearance times between the reflex hypotensive responses from catecholamine injections into the isolated coronary circulation and the direct hypertensive response from a similar injection when the circulations were connected as well as by the marked difference between the pressure pulses recorded simultaneously on both sides of the aortic balloon separating the two circulations.4.
(16) At the same time the duodenum can be isolated from the stomach and maintained under constant stimulus by a continual infusion at regulated pressure, volume and temperature into the distal cannula.
(17) Only the approximately 2.7 kb mRNA species was visualized in Northern blots of total cellular and poly(A+) RNA isolated from cardiac ventricular muscle.
(18) These major departmental transformations are being run in isolation from each other.
(19) This postulate is supported by a limited study of the serovars present among the isolates.
(20) Plasma membranes were isolated from rat kidney and their transport properties for sodium, calcium, protons, phosphate, glucose, lactate, and phenylalanine were investigated.
Solitude
Definition:
(a.) state of being alone, or withdrawn from society; a lonely life; loneliness.
(a.) Remoteness from society; destitution of company; seclusion; -- said of places; as, the solitude of a wood.
(a.) solitary or lonely place; a desert or wilderness.
Example Sentences:
(1) She wanted it used as a winter White House – a place where a president could find solitude and rest.
(2) The only sound was the breeze whispering to the grass: splendour in solitude.
(3) Solitude becomes a way of life and social interaction a scarce commodity for many chronic schizophrenics who are in institutional settings.
(4) I yearned for solitude; most of all, I wanted to sleep alone.
(5) A '"demi-alien", he began, in his solitude, to write a novel.
(6) You won't need a guide on the Petroglyph Point or Nordenskiold Site No 16 trails, where hikers can experience solitude among the primitive paintings and ruins.
(7) 'Solitude' was a measure of the time during each day when potential sources of help were spontaneously available.
(8) The years of solitude spent pushing others towards your goal, the decision to place yourself in harm's way (as in Stachel's case), and the constant threat of failure.
(9) Most important, Carlin says, Freeman, abetted by the screenwriter, "impressively conveys the giant solitude of Mandela".
(10) Eventually this marriage gets to old age in solitude, with the bitterness of loneliness."
(11) She doesn't mind being lonely – "if you call it solitude it doesn't seem so bad" – and she takes long walks, another of her salvations.
(12) Additional research is suggested to increase the generalizability of the findings of this study and to isolate conditions related to Orem's (1985) sets of actions for maintenance of a balance between solitude and social interaction.
(13) Symbiontic psychoses (induced delusions) are marked by 'solitude by twos'--together in alienation to the environment.
(14) But it was Salinger's own war that seems to have perpetuated his adolescence, trapping him in the mind and spirit of a disaffected teen and subsequently sponsoring a deep yearning for solitude.
(15) The differences in general activity were detected after 69 and 79 days of social deprivation; the hyperactivity induced by amphetamine was greater after 79 days of isolation and the pentylenetetrazol CD50's were higher after 56, 69 and 79 days of solitude.
(16) This resulted in the isolation of provincial psychiatric hospitals, general hospital psychiatric units and community mental health programs, with little overall accountability for the services provided--three solitudes.
(17) Either you play your difference for all it is worth, or you retreat into solitude.
(18) Photograph: National Trust What do you do if you hanker after a dose of solitude somewhere scenic and remote, but can no longer heft a heavy rucksack because of a dodgy back?
(19) Distinct hypochondriac and relation delusions evolved and the feeling of solitude increased.
(20) After a standing ovation and several prizes at Sundance, this quiet little film about a very small man who gets so fed up with people's reaction to his tiny size that he decides to live in total solitude, has made its way around the world as an example of the kind of American cinema you now hardly ever see.